 | B.J. Ward als Velma Dinkley (voice) |
 | Ed Gilbert als Mr. Beeman (voice) |
 | Tara Strong als Lena Dupree (voice) |
 | Adrienne Barbeau als Simone (voice) |
 | Mary Kay Bergman als Daphne Blake (voice) |
 | Scott Innes als Scooby-Doo (voice) |
 | Frank Welker als Fred Jones (voice) |
 | Billy West als Shaggy Rogers (voice) |
 | Jim Cummings als Jacques (voice) |
 | Cam Clarke als Beau Neville (voice) |
 | Jennifer Leigh Warren als Chris (voice) |
 | Mark Hamill als Snakebite Scruggs (voice) |
| Kazumi Fukushima | Director |
| Jim Stenstrum | Director |
| Cosmo Anzilotti | Producer |
| Davis Doi | Story |
| Glenn Leopold | Screenplay |
| Victoria McCollum | Associate Producer |
| Jean MacCurdy | Executive Producer |
| Davis Doi | Supervising Producer |
| Steven Bramson | Original Music Composer |
| Paul Douglas | Editor |
| Takashi Maekawa | Special Effects |
| Isao Yamamoto | Special Effects |
| Glenn Leopold | Story |
| William Hanna | Characters |
| Joseph Barbera | Characters |
| Steven Bramson | Conductor |
| Kris Zimmerman | Other |
| Collette Sunderman | Casting |
| Diana Ritchey | Production Manager |
| Robert Alvarez | Animation Director |
| James T. Walker | Animation Director |
| Armando Carrillo | Storyboard Artist |
| Adrian Gonzales | Storyboard Artist |
| Mario Piluso | Storyboard Artist |
| Lane Raichert | Storyboard Artist |
| Andrew Gentle | Background Designer |
| Derek Carter | Background Designer |
| Bobby Scott | Background Designer |
| Bill Williams | Background Designer |
| Paula LaFond | Character Designer |
| Mordecai Brown | Character Designer |
| Vaughn Tada | Character Designer |
| Lance Falk | Modeling |
| Iwao Takamoto | Creative Consultant |
| Steve Swaja | Prop Designer |
| Lee Go | Prop Designer |
| Scott Hill | Prop Designer |
| Al Gmuer | Other |
| Mannix Bennett | Other |
| Bonnie Callahan | Other |
| Brendan Eaton | Other |
| Craig Gardner | Other |
| Andrew Phillipson | Other |
| Charles E. Pickens | Other |
| Matthew Somma | Other |
| Henrik Tamm | Other |
| Stephan Jenkins | Songs |
| Brad Hargreaves | Songs |
| Kevin Cadogan | Songs |
| Arion Salazar | Songs |
| Tom Snow | Music |
| Glenn Leopold | Lyricist |
| Richard Mouser | Music Producer |
| Steve Isaacs | Music Producer |
| Sven Shenar | Music Producer |
| Kelly Castro | Music Producer |
| Chris Cano | Music Producer |
| Rob Brown | Music Producer |
| Steve Isaacs | Songs |
| Sven Shenar | Songs |
| Kelly Castro | Songs |
| Chris Cano | Songs |
| Rob Brown | Songs |
| Dave Jordan | Music Consultant |
| Stephen DePace | Music Consultant |
| John Richards | Scoring Mixer |
| Ruth Oroshnik | Orchestrator |
| Michael Patterson | Orchestrator |
| David Slonaker | Orchestrator |
| Bruce Frazier | Music Editor |
| Jamy Huang | Other |
| Harry NIckelson | Other |
| Lori Hanson | Painter |
| Nelda Ridley | Painter |
| Kunio Shimamura | Animation Director |
| Hiroshi Aoyama | Director |
| Shu-Bee Lee | Production Coordinator |
| Tohru Ishida | Assistant Director |
| Yoshishige Kosako | Animation Director |
| Kiyoshi Nakamura | Animation Director |
| Ben Raleigh | Music |
| David Mook | Music |
| Tim Iverson | Post-Production Manager |
| Julianne Humbert | Post Production Coordinator |
| Pat Foley | Additional Editing |
| Kerry Iverson | Assistant Editor |
| Jim Hearn | Dialogue Editor |
| Kerry Iverson | Dialogue Editor |
| Jim Hearn | ADR Editor |
| Tim Gedemer | Sound Effects Designer |
| Rick Hinson | Sound Effects Editor |
| Vincent Giusette | Foley Artist |
| Richard Duarte | Foley Mixer |
| William DeBoer, Jr. | Negative Cutter |
| Lu Palazzola | Negative Cutter |
| Allen L. Stone | Sound Re-Recording Mixer |
| Michael Jiron | Sound Re-Recording Mixer |
| William Olson | Sound Recordist |
| Trent Johnson | Colorist |
| Cheryl Campsmith | Online Editor |
| Michael Diaz | Production Assistant |
| Sharra Gage | Production Assistant |
| Lisa Melcombe | Production Assistant |
| Linda Moore | Production Assistant |
| Barbara Bartz | Production Assistant |
| Nancy Grimaldi | Production Assistant |
| Joanne Halcon | Production Accountant |
| Amy E. Wagner | Other |
| Athena Christianakis | Administration |
| Maria Womack | Administration |
| Haven Alexander | Production Supervisor |
| Ken Duer | Production Supervisor |
| Clive Nakayashiki | Production Supervisor |
| Joe Sandusky | Production Supervisor |
| Howard Schwartz | Production Supervisor |
| Liza-Ann Warren | Production Supervisor |
| Andy Lewis | Production Manager |
| Brian A. Miller | Executive In Charge Of Production |
| Don Messick | In Memory Of |
