 | Simu Liu als Shaun / Shang-Chi |
 | Awkwafina als Katy Chen |
 | Meng'er Zhang als Xu Xialing |
 | Fala Chen als Ying Li |
 | Florian Munteanu als Razor Fist |
 | Benedict Wong als Wong |
 | Yuen Wah als Master Guang Bo |
 | Michelle Yeoh als Ying Nan |
 | Ben Kingsley als Trevor Slattery |
 | Tony Leung Chiu-wai als Xu Wenwu / The Mandarin |
 | Andy Le als Li Ching-Lin / Death Dealer |
 | Paul He als Chancellor Hui |
 | Jayden Tianyi Zhang als Young Shang-Chi |
 | Elodie Fong als Young Xialing |
 | Arnold Sun als Teen Shang-Chi |
 | Stephanie Hsu als Soo |
 | Kunal Dudheker als John |
 | Tsai Chin als Waipo |
 | Jodi Long als Mrs. Chen |
 | Dallas Liu als Ruihua |
 | Ronny Chieng als Jon Jon |
 | Stella Ye als Yuchen |
 | Fernando Chien als Gao Lei |
 | Michael-Anthony Taylor als Bus Driver |
 | Zach Cherry als Clev |
 | Raymond Ma als Gang Leader |
 | Lau Ga-Yung als Wenwu's Captain |
 | Johnny Carr als Wenwu's Driver |
 | Harmonie He als Teen Xialing |
 | Lydia Sarks als Flight Attendant |
 | Dee Bradley Baker als Morris (voice) |
 | Jade Xu als Widow |
 | Tim Roth als Emil Blonsky / Abomination (voice) (uncredited) |
 | Mark Ruffalo als Bruce Banner / Hulk (uncredited) |
 | Brie Larson als Carol Danvers / Captain Marvel (uncredited) |
 | David Chea als Bus Goon (uncredited) |
 | Bingchen Ye als Archer Warrior / Assassin (uncredited) |
 | Daniel Liu als BMW Driver |
 | Benjamin Wang als Gang Member |
| Kevin Feige | Producer |
| Steve Englehart | Characters |
| Jim Starlin | Characters |
| Destin Daniel Cretton | Director |
| Sue Chan | Production Design |
| Kym Barrett | Costume Design |
| Chelsea Staebell | Costume Assistant |
| Anissa Garcia | Casting Assistant |
| Keith Lau | Concept Artist |
| Liz Oliver | Textile Artist |
| Chung Chi Li | Stunt Coordinator |
| Andrew Campbell | Graphic Designer |
| Iona Harris | Producer's Assistant |
| Ulrich Zeidler | Conceptual Design |
| Dave Heazlewood | Transportation Captain |
| Brianna Hoskins | Production Coordinator |
| Jocelyn Kuan | Costume Assistant |
| Christopher Kelley | Set Decoration Buyer |
| Chung Chi Li | Second Assistant Director |
| Chelsea Staebell | Assistant Costume Designer |
| Fabian Lacey | Concept Artist |
| Susan Lee | Textile Artist |
| Jennifer Cornwell | Unit Production Manager |
| Grace Waing | Art Department Assistant |
| Andy Park | Visual Development |
| Jeff Okabayashi | First Assistant Director |
| Damien Carr | Visual Effects Producer |
| Christopher Townsend | Visual Effects Supervisor |
| Salvatore Salamone | Key Costumer |
| Lori A. Balton | Location Scout |
| Richard Hobbs | Supervising Art Director |
| Molly Doyle | Casting Associate |
| Romana Samaritani | Executive Assistant |
| Whitney Donald | Art Department Assistant |
| Kirby Feagan | Assistant Art Director |
| Edwin Van Huizen | Colorist |
| Charles Newirth | Executive Producer |
| Sean Hargreaves | Conceptual Design |
| Bradley James Allan | Stunt Coordinator |
| Esther Marquis | Textile Artist |
| Marianne Parker | Costumer |
| Jade Xu | Stunts |
| Joy Cretton | Costume Designer |
| Bill Pope | Director of Photography |
| Jonathan Schwartz | Producer |
| Louis D'Esposito | Executive Producer |
| Victoria Alonso | Executive Producer |
| Destin Daniel Cretton | Screenplay |
| Dave Callaham | Screenplay |
| Bradley James Allan | Second Unit Director |
| Joel P. West | Original Music Composer |
| Mike Snow | Stunts |
| Dave Jordan | Music Supervisor |
| Nat Sanders | Editor |
| Elísabet Ronaldsdóttir | Editor |
| Harry Yoon | Editor |
| David J. Grant | Co-Producer |
| Sarah Halley Finn | Casting |
| Andrew Lanham | Screenplay |
| Andy Cheng | Fight Choreographer |
| Eliza Campagna | Makeup Artist |
| Quinton Wallace | Makeup Artist |
| Katy Wood | Supervising Sound Editor |
| Jeremy Bowker | Sound Designer |
| Dave Callaham | Screenstory |
| Destin Daniel Cretton | Screenstory |
| Matt Fraction | Thanks |
| Bradley James Allan | In Memory Of |
| Dan Finnegan | VFX Artist |
| Alexandre Cancado | Visual Effects Supervisor |
| Cecilia Chi-ying Lau | Casting Assistant |
| Kay Hoddy | Rotoscoping Artist |
| Yung Lee | Fight Choreographer |
| Puven Pather | Stunts |
| Fiona Nix | Unit Publicist |
| Courtney Mayhew | Unit Publicist |
| Anthony Rose | Epk Camera Operator |
| Michael Semanick | Additional Sound Re-Recording Mixer |
| Peter J. Devlin | Sound Re-Recording Mixer |
| Lora Hirschberg | Sound Re-Recording Mixer |
| Sona Balam | Sound Re-Recording Mixer |
| Onnalee Blank | Sound Re-Recording Mixer |
| Danielle Adams | Sound Re-Recording Assistant |
| Xing Zhaolin | Stunts |
| Finola Xie | Stand In |
| Fan Xiaoshuang | Stunt Double |
| Angela Sippel | Stunts |
| Lauren Shaw | Stunts |
| Kelly Richardson | Stunts |
| Yvette Lutonadio | Stunts |
| Millie Lohmann | Stunt Double |
| Shao-Yan Li | Stunt Double |
| Charlotte Leonie | Stunts |
| Lucy Lantz | Stunts |
| Catherine Hewitson | Stunts |
| Michelle Jubilee Gonzalez | Stunts |
| Robin Lynn Bonaccorsi | Stunts |
| Mark Dawson | Art Direction |
| Mike Martinez | Stunts |
| Liam Lane | Other |
| David Mir | Digital Compositor |
| Meow Nutjaree Wannasri | VFX Artist |
| Kevin R. Wright | Other |
| Todd Harris | Storyboard Artist |
| Talayna Moana Nikora | Stunts |
| Beau Karolos | Stunts |
| Rebecca Cohen | Decorator |
