 | Johnny Depp als Sherlock Gnomes (voice) |
 | Emily Blunt als Juliet (voice) |
 | James McAvoy als Gnomeo (voice) |
 | Chiwetel Ejiofor als Watson (Voice) |
 | Mary J. Blige als Irene (voice) |
 | Stephen Merchant als Paris (voice) |
 | Michael Caine als Lord Redbrick (voice) |
 | Dexter Fletcher als Gargoyle Reggie (voice) |
 | James Hong als Salt Shaker (voice) |
 | Ashley Jensen als Nanette (voice) |
 | Matt Lucas als Benny (voice) |
 | Ozzy Osbourne als Fawn (voice) |
 | Maggie Smith als Lady Bluebury (voice) |
 | Julie Walters als Mrs. Montague (voice) |
 | Jamie Demetriou als Moriarty (voice) |
 | Richard Wilson als Mr. Capulet (voice) |
 | Kelly Asbury als Goons |
| Elton John | Music |
| Mark Solomon | Editorial Manager |
| Romain Joly | Visual Effects |
| Corey Turner | Visual Effects |
| Elton John | Producer |
| David Furnish | Producer |
| Steve Hamilton Shaw | Producer |
| Gary Dunn | Art Direction |
| Carolyn Soper | Producer |
| Dougal Cadiou | Production Accountant |
| Kat Seale | Animation |
| Gianluca Fratellini | Animation |
| Ben Zazove | Screenplay |
| Slaven Reese | Animation |
| Kelly Asbury | Creative Consultant |
| Xin Zhao | Animation |
| John Stevenson | Director |
| Emily Cook | Story |
| Kelly Asbury | Characters |
| Kevin Cecil | Story |
| Steve Hamilton Shaw | Characters |
| Kevin Cecil | Characters |
| Rob Sprackling | Characters |
| Andy Riley | Story |
| Kathy Greenberg | Story |
| Andy Riley | Characters |
| Johnny Smith | Characters |
| Arthur Conan Doyle | Characters |
| William Shakespeare | Characters |
| Uli Meyer | Storyboard Artist |
| Aya Suzuki | Storyboard Artist |
| Chris Bacon | Music |
| Nina Gold | Casting |
| Niv Adiri | Sound Re-Recording Mixer |
| Lilly Blazewicz | Foley Editor |
| Adam Armitage | Sound Effects Editor |
| Peter Burgis | Foley Editor |
| Zoe Freed | Foley Artist |
| Gillian Dodders | Dialogue Editor |
| Glenn Freemantle | Sound Designer |
| Nick Freemantle | Sound Effects Editor |
| Tim Hands | Dialogue Editor |
| Jemma Riley-Tolch | Assistant Foley Artist |
| Jason Swanscott | Foley Artist |
| Ian Tapp | Sound Re-Recording Mixer |
| Eamonn O'Neill | Title Designer |
| Kristian Andrews | Title Designer |
