 | Robert De Niro als Det. Mitch Preston |
 | Eddie Murphy als Officer Trey Sellars |
 | Rene Russo als Chase Renzi |
 | William Shatner als William Shatner |
 | Nestor Serrano als Ray |
 | Joy Bryant als Lexi |
 | Yasiin Bey als Lazy Boy |
 | Rachael Harris als Lehrerin |
 | Peter Jacobson als Brad Slocum |
 | Drena De Niro als Annie |
 | Frankie Faison als Lt. Winship |
 | T.J. Cross als ReRun |
 | Judah Friedlander als Julio |
 | James Roday Rodriguez als 'Maxis' Cameraman |
 | Alex Borstein als Casting Director |
 | Kadeem Hardison als Kyle |
 | Pedro Damián als Ceasar Vargas |
 | Johnnie Cochran als Himself |
 | Merlin Santana als Hector |
 | Zaid Farid als Polizeichef Ben |
| Holly Mandel als Producer |
| Joel Hurt Jones als Reporter #1 |
| Chris Harrison als Reporter #2 |
| Perri Peltz als Reporter #3 |
| Amy Powell als Reporter #4 |
| Debra Snell als Reporter #5 |
 | Chris Ufland als Reporter #6 |
 | Andrew Wilson als Locker Room Cop #1 |
 | Larry Joe Campbell als Locker Room Cop #2 |
 | Reggie Gaskins als Locker Room Cop #3 |
 | Ken Hudson Campbell als Cop in Gym |
| Johnnie L. Cochran Jr. als Johnnie Cochran, ReRun's Lawyer |
 | Rick Cramer als Duty Officer |
 | Linda Hart als Waitress |
 | Maurice Compte als Chili |
| Freez Luv als Freez |
 | Jullian Dulce Vida als J.J. |
| Jeff Sanders als Big Boy |
 | Robert Joseph als Gangbanger #4 |
 | Angela Alvarado als Gina Reyes |
 | John Cariani als Charlie Hertz |
 | Kirk Ward als Parking Garage Cop #1 |
| Reggie Jordan als Parking Garage Cop #2 |
 | Lucille M. Oliver als Screaming Woman |
| Callie Childers als Pool Girl |
 | Tom Billett als Freddy, Bouncer #2 |
 | Henry Kingi als Garbage Truck Driver |
| Neil Mather als Uniform |
| Joel Elliott als Animal Welfare Worker #1 |
| Grant Sawyer als Animal Welfare Worker #2 |
 | Christopher Darga als Gun Show Announcer |
 | Clement Blake als Gun Show Patron |
 | Lisa Renee Pitts als Female Cop #1 |
| Teresa DePriest als Female Cop #2 |
 | John Polce als Police Officer |
 | Greg Bronson als Detective (uncredited) |
| Heather Charles als Model (uncredited) |
 | Lisa Danielle als (uncredited) |
| Jackie Di Crystal als Salsa Dancer (uncredited) |
| Sonya Khazaal als Salsa Dancer (uncredited) |
 | Pui Fan Lee als Mrs. Maggie Snow (uncredited) |
| Christie McNew als Nightclub Patron (uncredited) |
| Erica Taylor als Nightclub Patron (uncredited) |
 | Marshall Manesh als Convenience Store Owner |
| Tom Dey | Director |
| Keith Sharon | Screenplay |
| Alfred Gough | Screenplay |
| Miles Millar | Screenplay |
| Bruce Berman | Executive Producer |
| Channing Dungey | Producer |
| James Lassiter | Executive Producer |
| Eric McLeod | Executive Producer |
| Jane Rosenthal | Producer |
| Jorge Saralegui | Producer |
| Will Smith | Executive Producer |
| Thomas Kloss | Director of Photography |
| Billy Weber | Editor |
| Ellen Chenoweth | Casting |
| Jeff Mann | Production Design |
| Geoff Hubbard | Art Direction |
| David Sandefur | Art Direction |
| Tessa Posnansky | Set Decoration |
| Christopher Lawrence | Costume Design |
| Alan Silvestri | Original Music Composer |
| Katherine E. Beyda | Unit Production Manager |
| Josh King | First Assistant Director |
| Marcei A. Brown | Second Assistant Director |
| Michael McQuarn | Music Supervisor |
| Joel Sill | Music Supervisor |
| Jack Gill | Stunt Coordinator |
| Gregory S. Hooper | Assistant Art Director |
| George Lee | Set Designer |
| William Hiney | Set Designer |
| Nick Navarro | Set Designer |
| Beck Taylor | Set Designer |
| Jonathan Bobbitt | Leadman |
| Mark Davison | "A" Camera Operator |
| Chris Toll | First Assistant "A" Camera |
| Renee Treyball | Second Assistant "A" Camera |
| David Luckenbach | "B" Camera Operator |
| David Luckenbach | Steadicam Operator |
| Calmar Roberts | First Assistant "B" Camera |
| Jeff Pelton | Second Assistant "B" Camera |
| Bruce McBroom | Still Photographer |
| Luca Kouimelis | Script Supervisor |
| Alfred Ainsworth | Video Assist Operator |
| Steve Cantamessa | Production Sound Mixer |
| Gary Thomas | Boom Operator |
| Norman Harris | Chief Lighting Technician |
| Valerie Zielonka | Costume Supervisor |
| Tom Numbers | Costume Supervisor |
| Rena Andreoli | Makeup Department Head |
| Cheryl Ann Nick | Makeup Artist |
| Shane Paish | Makeup Artist |
| Ilona Herman | Makeup Artist |
| Vera Steimberg | Makeup Artist |
| Michelle Weiss | Hair Department Head |
| Catherine Marcotte | Hairstylist |
| Enzo Angileri | Hairstylist |
| Robert J. Carlyle | Construction Coordinator |
| Michael Meinardus | Special Effects Coordinator |
| John M. Woodward | Transportation Coordinator |
| Sande Alessi | Extras Casting |
| Gena Bleier | First Assistant Editor |
| J. Paul Huntsman | Supervising Sound Editor |
| Christopher S. Aud | Supervising Sound Editor |
| Kimberly Harris | Supervising ADR Editor |
| Patrick J. Foley | Dialogue Editor |
| Gloria D'Alessandro | Dialogue Editor |
| Jayme S. Parker | Sound Effects Editor |
| Adam Johnston | Sound Effects Editor |
| David M. Horton | Foley Editor |
| David Horton Jr. | Foley Editor |
| John P. Fasal | Sound Designer |
| John T. Reitz | Sound Re-Recording Mixer |
| David E. Campbell | Sound Re-Recording Mixer |
| Gregg Rudloff | Sound Re-Recording Mixer |
| Alan Silvestri | Orchestrator |
| Mark McKenzie | Orchestrator |
| Jamie Dixon | Visual Effects Supervisor |
| Jacqui Lopez | Visual Effects Producer |
| Mo Henry | Negative Cutter |
| David Orr | Color Timer |
| James Logan | Utility Stunts |
| Chrisie Paola | Stunts |
| Gina Mari | Stunts |
| Anita Hart | Stunts |
| Glory Fioramonti | Stunts |
| Cheryl Wheeler Duncan | Stunts |
| Christal Chacon | Stunts |
| Joni Avery | Stunts |
| Jophery C. Brown | Stunts |
| Charlie Picerni | Stunts |
| Rick Avery | Stunts |
| Bob Brown | Stunts |
| Andy Gill | Stunt Double |
| Jack Gill | Second Unit Director |
| Steve M. Davison | Stunts |
| John Cenatiempo | Stunts |
| Janet Brady | Stunts |
| Danny Epper | Stunts |
| Kenny Endoso | Stunts |
| Dane Farwell | Stunts |
| Danny Wynands | Stunts |
| Corey Michael Eubanks | Stunts |
| Pat Romano | Stunts |
| Norman Howell | Stunts |
