 | Robin Dunne als Dean |
 | Robert Knepper als Dr. Abbot |
 | Sunny Mabrey als Sara |
 | Amelia Cooke als Amelia |
 | Christopher Neame als Dr. Nicholas Turner |
 | Patricia Bethune als Colleen |
 | Michael Warren als Agent Wasach |
 | Natasha Henstridge als Eve |
 | John Paul Pitoc als Hastings |
 | Joel Stoffer als Portus |
 | James Leo Ryan als Yosef |
| Savanna Fields als Young Sara |
| Reed Frerichs als ISD Staffer |
| Marc D. Wilson als Crew Chief |
 | Matthew Yang King als Specialist Robert Kelley |
| Rick Dean als Cobb the Gas Station Guy |
| Christopher R. Gillum als Young Portus |
| Billy Bacon als Commander |
| Jim Cody Williams als Farmer at Gas Station |
| Mark Zecca als Tour Guest |
| Sean C. Ching als Grad Student |
| Dan Wells als Jake |
| Frank Crim als Communications Officer |
 | Boni Yanagisawa als Female Student |
| Rob Hinderstein als Security Guard #1 |
 | Carl Ciarfalio als Security Guard #2 |
 | Troy Blendell als Autopsy Tech |
| Keith Camire als Military Soldier (uncredited) |
| Josh Cook als Jock (uncredited) |
| Joss Gomez als Student (uncredited) |
| Kari Ann Peniche als Cheerleader (uncredited) |
| Jason Sarcinelli als Adult Male Alien (uncredited) |
| Marc Scizak als Football Player (uncredited) |
| David Dwiggins | Producer |
| Elia Cmiral | Music |
| Frank Mancuso Jr. | Executive Producer |
| Brad Turner | Director |
| Richard Redlefsen | Lead Painter |
| Dennis Feldman | Characters |
| James Coblentz | Editor |
| Ben Ripley | Author |
| Paul Weber | Casting |
| Ivy Isenberg | Casting Associate |
| Joel Harlow | Creature Design |
| Joel Harlow | Special Effects Makeup Artist |
| Jalil Jay Lynch | Stunts |
| George Hesse | First Assistant Camera |
| Todd Rex | Sculptor |
| Sarah McMurdo | Visual Effects Coordinator |
| Theo Kypri | Stunts |
| Halina Siwolop | Set Decoration |
| Zora DeHorter | Casting |
| Dennis Berardi | Visual Effects Supervisor |
| Cameron Birnie | Production Design |
| Noel Vought | Foley Artist |
| Debbie Evans | Stunts |
| Kathleen Crawford | Makeup Department Head |
| Allan Magled | Visual Effects Supervisor |
| Brent Rice | Leadman |
| Eric J. Robertson | Visual Effects Producer |
| Gregory C. Tippie | Special Effects Coordinator |
| Michael Kowalski | Visual Effects Producer |
| Saeed Adyani | Still Photographer |
| Mark Lanza | Sound Effects Editor |
| Jorge Razon | 3D Animator |
| Ken Glassing | Director of Photography |
| Ken Glassing | Camera Operator |
| Jeff Rosen | Sound Effects Editor |
| Maggie Hayes-Jackson | Key Hair Stylist |
| Rob Hinderstein | Creature Design |
| Jim Vickers | Choreographer |
| Jim Vickers | Stunt Coordinator |
| Jim Vickers | Fight Choreographer |
| Paul Drenning | ADR Mixer |
| Jeff Jingle | Animatronics Supervisor |
| Boni Yanagisawa | Utility Stunts |
| Paul Janossy | First Assistant Camera |
| Marc Scizak | Stunts |
| Victor Iorillo | Supervising Sound Editor |
| Phillip W. Palmer | Production Sound Mixer |
| John Bocchicchio | Set Medic |
| Marla McGuire | ADR Editor |
| Barb Benoit | Digital Compositor |
| Jeff Hay | Set Dresser |
| Kurt Kassulke | Sound Re-Recording Mixer |
| Thomas D. Krausz | Set Dresser |
| Daniel Lu | 3D Animator |
| David S. DiPietro | ADR Recordist |
| Keith Sellers | 3D Animator |
| Scott W. Leslie | Set Dresser |
| Kristy Blackwell | CG Supervisor |
| Jef Lonn | Digital Compositor |
| Betsy Bagg | Casting Assistant |
| Mark Della Rosa | 3D Animator |
| Heather Cappiello | Script Supervisor |
| John Tamburro | Pilot |
| Timothy Pearson | Foley Artist |
| Gary A. Williams | Dolly Grip |
| Amy De Souza | Casting Assistant |
| Brad Kenny | Extras Casting |
| Steve Wittmann | CG Animator |
| Matt Ralph | 3D Animator |
| Kent Nelson | Key Hair Stylist |
| Kay Kropp | Lead Painter |
| Julián Navarro | On Set Dresser |
| Brendan C. Fenton | On Set Dresser |
| Maret Wicken | Painter |
| Gary Antista | Property Master |
| Jeannine Stevens | Set Dresser |
| Stacey Michaels | Foley Mixer |
| Derek Sunderland | 3D Animator |
| Karl Sisson | CG Artist |
| Mike Mombourquette | Digital Compositor |
| Greg McCurley | Lighting Technician |
| Randy Beveridge | Colorist |
| Michelle Walsh | Assistant Editor |
