 | James McAvoy als Kevin Wendell Crumb |
 | Anya Taylor-Joy als Casey Cooke |
 | Betty Buckley als Karen Fletcher |
 | Haley Lu Richardson als Claire Benoit |
 | Jessica Sula als Marcia |
 | Izzie Coffey als Five-Year-Old Casey |
 | Brad William Henke als Uncle John |
 | Sebastian Arcelus als Casey's Father |
 | Neal Huff als Mr. Benoit |
 | Ukee Washington als News Anchor |
 | Ann Wood als Game Show Enthusiast |
| Robert Michael Kelly als Joe |
 | M. Night Shyamalan als Jai, Hooters Lover |
 | Rosemary Howard als Kevin's Mother |
| Jerome Gallman als Vince, Security Guard |
 | Lyne Renee als Academic Moderator |
| Kate Jacoby als Dr. Fletcher's Patient |
 | Peter Patrikios als Taxi Driver |
 | Kash Goins als Flower Kiosk Worker |
 | Roy James Wilson als Security Guy with Dog |
| Christopher Lee Philips als Older Worker |
| Julie Potter als Paramedic |
| Ameerah Briggs als Police Officer #1 |
 | Nakia Dillard als Police Officer #2 |
 | Robin Rieger als Television Reporter |
| Emlyn Elisabeth Morinelli als Diner Waitress |
 | Dann Fink als Game Show Contestant (voice) |
 | Bruce Winant als Game Show Host (voice) |
 | Bruce Willis als David Dunn (uncredited) |
| Kelly Werkheiser als Casey's Mother (uncredited) |
 | Kim Director als Hannah (uncredited) |
 | Robert Bizik als Bar Patron (uncredited) |
| Junnie Lopez als Geraldo (uncredited) |
| Steven Dennis als Dan at Next Table (uncredited) |
| Matthew Nadu als Waiter (uncredited) |
| Barbara Edwards als Diner Patron (uncredited) |
| James Robinson Jr. als Claire's Party Guest (uncredited) |
| Corinne Costa als Party Guest (uncredited) |
| John Mitchell als EMT (uncredited) |
 | Andrea Havens als Traveler in the Station (uncredited) |
| Shawn Gonzalez als Train Conductor (uncredited) |
| Aleksandra Svetlichnaya als Pedestrian (uncredited) |
 | Jalina Mercado als Zoo Goer (uncredited) |
| Michael J. Kraycik als Zoo Worker (uncredited) |
| Michaela Bockarie als Zoo Attendee (uncredited) |
| Colin Campbell als Boy in Park (uncredited) |
| John Jillard Sr. als Homeland Security (uncredited) |
 | Vincent Riviezzo als Detective (uncredited) |
 | Gary Ayash als Restaurant Patron (uncredited) |
| Jeff Buckner als Police Officer (uncredited) |
| M. Night Shyamalan | Director |
| M. Night Shyamalan | Writer |
| Jason Blum | Producer |
| Ashwin Rajan | Executive Producer |
| Steven Schneider | Executive Producer |
| M. Night Shyamalan | Producer |
| Luke Ciarrocchi | Editor |
| Douglas Aibel | Casting |
| Mara LePere-Schloop | Production Design |
| Jesse Rosenthal | Art Direction |
| Jennifer Engel | Set Decoration |
| Dennis Madigan | Set Decoration |
| Paco Delgado | Costume Design |
| Phillip Dawe | Executive In Charge Of Post Production |
| Matthew Shapiro | Post Production Supervisor |
| John Burton West | Unit Production Manager |
| Nicole Agostino | Assistant Director |
| Amy Lauritsen | Assistant Director |
| John Rusk | Assistant Director |
| Dave Kellom | Art Department Coordinator |
| Nicole Reed LeFevre | Set Designer |
| Paul Maiello | Construction Coordinator |
| Alex Alcántara | ADR & Dubbing |
| Toño Cubillo | ADR & Dubbing |
| Rodrigo Díaz | ADR & Dubbing |
| Tod A. Maitland | Sound Mixer |
| Wyatt Sprague | Sound Recordist |
| Jerry Yuen | Boom Operator |
| Kurt Wunder | Special Effects Coordinator |
| Anteneh Adamu | Compositors |
| Richard Aponte | VFX Artist |
| Tyler Lockard | Compositors |
| Ed Mendez | Visual Effects Supervisor |
| Colton Miller | VFX Supervisor |
| Jennifer Wessner | Visual Effects Producer |
| Stephen Izzi | Stunts |
| Manny Siverio | Stunt Coordinator |
| Thomas Devine | Electrician |
| Andy Hensler | Additional Camera |
| Linda Källérus | Still Photographer |
| Michael Leonard | First Assistant Camera |
| Ryan 'Sparks' Lynch | Lighting Technician |
| Daniel Rieser | Grip |
| Kyle Rudolph | Camera Operator |
| Colleen Kay | Casting Associate |
| Ken McCallum | Dolly Grip |
| Jon Sibert | Key Grip |
| Teresa Binder Westby | Assistant Costume Designer |
| Rita Squitiere | Costume Supervisor |
| Angeline Zeigler | Set Costumer |
| Kara Morasco | Tailor |
| Diane Dixon | Hair Department Head |
| Pamela Peitzman | Makeup Department Head |
| Susannah McCarthy | Property Master |
| Sharon Potts | Assistant Property Master |
| Lawrence Zipf | Sound Effects Editor |
| Rachel Ambelang | VFX Editor |
| Aaron Becker | Title Designer |
| Mike Gioulakis | Director of Photography |
| Pepe Pleguezuelos | Supervising Dialogue Editor |
| Charles S. Rowe | Script Supervisor |
| Dom Catanzarite | Associate Producer |
| Kevin Scott Frakes | Executive Producer |
| Buddy Patrick | Executive Producer |
| West Dylan Thordson | Original Music Composer |
| Staci Hagenbaugh | Location Manager |
| Joshua Clarke | Location Scout |
| Susan Jacobs | Music Supervisor |
| Kathryn Cates | Assistant Editor |
| Bryan Baker | Assistant Editor |
| Henry Russell Bergstein | Casting Associate |
| Diane Heery | Local Casting |
| Jason Loftus | Local Casting |
| Mark Lieberman | Compositors |
| Alejandro Monzon | Compositors |
| Steve F.B. Smith | Sound Designer |
| Janice Innella | Key Hair Stylist |
| Ray Santoleri | Makeup Artist |
| John Baer | Still Photographer |
| Skip Lievsay | Supervising Sound Editor |
| Brick Mason | Storyboard Artist |
| Michael Feuser | Dialogue Editor |
| Marc Bienstock | Producer |
