 | William Shatner als Admiral James T. Kirk |
 | Leonard Nimoy als Captain Spock |
 | DeForest Kelley als Dr. Leonard 'Bones' McCoy |
 | James Doohan als Captain Montgomery 'Scotty' Scott |
 | George Takei als Cmdr. Hikaru Sulu |
 | Walter Koenig als Cmdr. Pavel Chekov |
 | Nichelle Nichols als Cmdr. Uhura |
 | Catherine Hicks als Dr. Gillian Taylor |
 | Mark Lenard als Ambassador Sarek |
 | Jane Wyatt als Amanda |
 | Majel Barrett als Cmdr. Chapel |
 | Robert Ellenstein als Federation Council President |
 | John Schuck als Klingon Ambassador |
 | Brock Peters als Admiral Cartwright |
 | Robin Curtis als Lt. Saavik |
 | Michael Snyder als Starfleet Communications Officer |
| Kirk R. Thatcher als Punk on Bus |
 | Michael Berryman als Starfleet Display Officer |
 | Madge Sinclair als Saratoga Captain (uncredited) |
 | Grace Lee Whitney als Commander Rand |
 | Jane Wiedlin als Alien Communications Officer |
 | Vijay Amritraj als Starship Captain |
| Nick Ramus als Saratoga Helmsman |
 | Philip Weyland als Tourist (uncredited) |
| Kimberly L. Ryusaki als Tourist (uncredited) |
 | Scott Devenney als Bob Briggs |
 | Monique DeSart als Madelaine (uncredited) |
| Bob Sarlatte als Waiter |
| Everett Lee als Cafe Owner |
| Joe Aubel | Art Direction |
| Donald Peterman | Director of Photography |
| John M. Dwyer | Set Decoration |
| Peter E. Berger | Editor |
| Harve Bennett | Screenplay |
| Leonard Rosenman | Original Music Composer |
| Peter Krikes | Screenplay |
| Nicholas Meyer | Screenplay |
| Leonard Nimoy | Director |
| Harve Bennett | Producer |
| Robert Fletcher | Costume Design |
| Jack T. Collis | Production Design |
| Peter Landsdown Smith | Production Design |
| Steve Meerson | Screenplay |
| Peter Landsdown Smith | Art Direction |
| Amanda Mackey | Casting |
| Kirk R. Thatcher | Associate Producer |
| Douglas Freeman | Construction Coordinator |
| Ken Ralston | Visual Effects Supervisor |
| Mel Efros | Unit Production Manager |
| Mark A. Mangini | Sound Effects |
| Armen Ksajikian | Musician |
| Eddie Hice | Stunts |
| Leonard Nimoy | Story |
| Harve Bennett | Story |
| Ralph Winter | Executive Producer |
| Brooke Breton | Associate Producer |
| Nilo Rodis-Jamero | Assistant Art Director |
| Jeff Dawn | Makeup Artist |
| Wes Dawn | Makeup Artist |
| Silvia Abascal | Hairstylist |
| Monique DeSart | Hairstylist |
| Deborah Holmes Dobson | Hairstylist |
| James Lee McCoy | Makeup Artist |
| Rolf John Keppler | Special Effects Makeup Artist |
| Rick Stratton | Makeup Artist |
| Richard Snell | Special Effects Makeup Artist |
| Carol A. O'Connell | Hairstylist |
| Frank Capra III | Second Assistant Director |
| Pat Kehoe | First Assistant Director |
| Douglas E. Wise | First Assistant Director |
| David J. Hudson | Sound Re-Recording Mixer |
| Noyan Cosarer | Sound Re-Recording Mixer |
| Mel Metcalfe | Sound Re-Recording Mixer |
| Alan Howarth | Sound Effects |
| Michael Lantieri | Special Effects |
| Terry Porter | Sound Re-Recording Mixer |
| John C. Meier | Stunt Double |
| R.A. Rondell | Stunt Coordinator |
| Chuck Picerni Jr. | Stunts |
| Sharon Schaffer | Stunts |
| Steve M. Davison | Stunts |
| Cliff Fleming | Stunts |
| Bennie Moore | Stunts |
| Gregory J. Barnett | Stunts |
| Spike Silver | Stunts |
| Bruce Birmelin | Still Photographer |
