 | Ray Chase als Twisted Fate |
 | Elspeth Eastman als Tristana |
 | Melissa Hutchison als Teemo |
 | Faye Mata als Lulu |
 | Fred Tatasciore als Graves |
 | Jason Marsden als Corki |
| Anton Borkel | Director |
| Dustin Wicke | Director |
| Adam Jay Epstein | Writer |
| Laurie Goulding | Executive Story Editor |
| Marianne Krawczyk | Executive Story Editor |
| John O'Bryan | Writers' Assistant |
| Odin Shafer | Writers' Assistant |
| Dana Luery Shaw | Idea |
| Dustin Wicke | Writers' Assistant |
| Juno Blees | Executive Producer |
| Shanti Blees | Executive Producer |
| Caleb Bouchard | Executive Producer |
| Laura De Young | Executive Producer |
| Veronica Foo | Executive Producer |
| Greg Killion | Executive Producer |
| Eric Krause | Executive Producer |
| Ariel Lawrence | Executive Producer |
| Jessica Liou | Associate Producer |
| Jaraad Nageer | Associate Producer |
| Sophie Robeson | Producer |
| Ryan Rubin | Producer |
| Danny Stolzman | Supervising Producer |
| Greg Street | Executive Producer |
| Kimberly Xiong | Line Producer |
| Leland Cox | Compositor |
| Kole Hicks | Music Director |
| Spencer Sturr | Editor |
| Dustin Wicke | Editor |
| Annis Naeem | Art Direction |
| Almu Redondo | Art Direction |
| Quy Ho | Concept Artist |
| Mindy Kang | Concept Artist |
| Marina Krivenko | Concept Artist |
| Marina Krivenko | Matte Painter |
| Rembert Montald | Storyboard Artist |
| Annis Naeem | Matte Painter |
| Ihor Pasternak | Concept Artist |
| Dustin Wicke | Storyboard Artist |
| Maisie Yang | Concept Artist |
| Mari Yang | Storyboard Artist |
| Sean Balas | Sound Supervisor |
| Patrick Ginn | Sound Mixer |
| Shannon Potter | Sound Designer |
| Piotr Karol Hurny | Visual Effects Camera |
| Imran Sajid | CG Supervisor |
| James Waterson | Visual Effects Supervisor |
| Bader Badruddin | Animation Supervisor |
| Lee Croudy | Layout Supervisor |
| Jason Hendrich | Animation Supervisor |
| Kayla Arenas | Casting Producer |
| David Lyerly | Casting Director |
| Hokan Lo | Additional Editor |
| Noah Gladstone | Music Producer |
| Adam Michalak | Music Producer |
| Tony Grinage | Other |
| Addie Sillyman | Other |