 | Leonardo DiCaprio als Howard Hughes |
 | Cate Blanchett als Katharine Hepburn |
 | Kate Beckinsale als Ava Gardner |
 | John C. Reilly als Noah Dietrich |
 | Alec Baldwin als Juan Trippe |
 | Alan Alda als Senator Ralph Owen Brewster |
 | Ian Holm als Professor Fitz |
 | Danny Huston als Jack Frye |
 | Gwen Stefani als Jean Harlow |
 | Jude Law als Errol Flynn |
 | Adam Scott als Johnny Meyer |
 | Matt Ross als Glenn Odekirk |
 | Kelli Garner als Faith Domergue |
 | Frances Conroy als Mrs. Hepburn |
 | Brent Spiner als Robert Gross |
 | Stanley DeSantis als Louis B. Mayer |
 | Edward Herrmann als Joseph Breen |
 | Willem Dafoe als Roland Sweet |
 | Kenneth Welsh als Dr. Hepburn |
 | J.C. MacKenzie als Ludlow |
 | Jacob Davich als Howard Hughes (9 yrs old) |
 | Amy Sloan als Howard Hughes' Mother |
 | Sam Hennings als HELL'S ANGELS Stunt Coordinator |
 | Joe Chrest als HELL'S ANGELS Director of Photography |
 | Rufus Wainwright als Cocoanut Grove Vocalist #1 |
 | Harry Strandjofski als Crony of Louis B. Mayer |
 | Vince Giordano als Cocoanut Grove Band Member |
 | Josie Maran als Cigarette Girl |
 | Justin Shilton als HELL'S ANGELS Pilot |
 | Arthur Holden als Radio Announcer |
 | Raymond Ducasse als Roscoe Turner |
 | Joseph P. Reidy als Aide to Howard |
 | Stéphane Demers als Maitre d' |
 | Yves Jacques als Waiter |
 | Loudon Wainwright III als Cocoanut Grove Vocalist #2 |
 | Jason Cavalier als Cocoanut Grove Patron |
 | Chris Ufland als Engineer |
| Al Dubois als Pan Am Executive #1 |
 | Alan Toy als Man on Crutches |
 | Sebastian Tillinger als Timer |
 | Francesca Scorsese als Little Girl |
| Charlotte Scott als Little Girl |
 | James Bradford als Uncle Willy |
 | Joe Cobden als Another Guest #1 |
 | Linda E. Smith als Another Guest #2 |
 | Alan Fawcett als Chairman MPA |
| Jordan St. James als Hughes' Aide at Censor Hearing |
 | David Purdham als Emcee |
 | Kevin O'Rourke als Spencer Tracy |
 | Lisa Bronwyn Moore als Noah's Wife |
 | Emma Campbell als Jack Frye's Wife, Helen |
| Martha Wainwright als Cocoanut Grove Vocalist #3 |
 | Vincent Laresca als Jorge |
 | Matt Holland als Hughes' Staff Person |
| Dennis St John als Custodian |
 | Keith Campbell als Marine |
| Al Vandecruys als Doctor |
 | James Rae als FBI Agent |
| Kathleen McAuliffe als Brewster's Maid |
 | Nellie Sciutto als Secretary |
 | Terry Haig als Another Senator |
| James McNamara als James McNamara (voice) |
 | John Koensgen als Pan Am Executive #2 |
| Vladimir Kuznetsov Smith als Caretaker |
| Mark Akeson als Caretaker |
| Jason Pollard als Caretaker |
 | Heather Petrone als Vivien Leigh (uncredited) |
 | Danielle Franke als Esquire Starlet (uncredited) |
| Meghan Elizabeth als Starlet (uncredited) |
 | Elizabeth DeCicco als Starlet (uncredited) |
| Elisa Dyann als Coat Check Girl (uncredited) |
 | Isabelle Champeau als Editor (uncredited) |
 | Al Coronel als Bi-Plane Mechanic (uncredited) |
| Gerardo Lo Dico als Military Officer (uncredited) |
 | Anne V. Coates als Howard Hughes' Film Editor (uncredited) |
| Martin Scorsese | Director |
| John Logan | Screenplay |
| Sanford R. Climan | Producer |
| Charles Evans Jr. | Producer |
| Graham King | Producer |
| Michael Mann | Producer |
| Howard Shore | Original Music Composer |
| Robert Richardson | Director of Photography |
| Ellen Lewis | Casting |
| Luca Tranchino | Art Direction |
| Francesca Lo Schiavo | Set Decoration |
| Sandy Powell | Costume Design |
| Thelma Schoonmaker | Editor |
| Dante Ferretti | Production Design |
| Morag Ross | Makeup Department Head |
| Lucie Robitaille | Casting |
| Cheryl Beasley Blackwell | Costume Supervisor |
| Robert Guerra | Supervising Art Director |
| Claude Paré | Supervising Art Director |
| Réjean Forget | Hairstylist |
| Michael Jackman | Post Production Supervisor |
| Viviane Vallée | Art Department Coordinator |
| Charlotte Raybourn | Art Department Coordinator |
| Gaétan Marsolais | Art Department Coordinator |
| Bill Iiams | Construction Coordinator |
| William J. Law III | Set Designer |
| David C. Potter | Leadman |
| Lucie Fournier | Sculptor |
| Christina Ann Wilson | Assistant Art Director |
| Doris Simard | Art Department Coordinator |
| Eugene Gearty | Supervising Sound Editor |
| Philip Stockton | Supervising Sound Editor |
| Travis Call | Sound Recordist |
| Giovanni Di Simone | Sound Recordist |
| Marko Costanzo | Foley |
| Jay Peck | Foley |
| Wyatt Sprague | Sound Effects Editor |
| Tom Fleischman | Sound Re-Recording Mixer |
| Ron Ames | Visual Effects Producer |
| Denise Ballantyne | Visual Effects Producer |
| Crys Forsyth-Smith | Visual Effects Producer |
| Julia Frey | Visual Effects Producer |
| Adam Gerstel | Visual Effects Editor |
| Kim Lee | Visual Effects Producer |
| Louis Morin | Visual Effects Producer |
| Scott Sohan | Visual Effects Editor |
| Robert Stromberg | Visual Effects Supervisor |
| Robert Legato | Visual Effects Supervisor |
| Mat Beck | Visual Effects Supervisor |
| Jean Frenette | Stunt Coordinator |
| Francois Archambault | Steadicam Operator |
| John Skotchdopole | Camera Operator |
| Andrew Cooper | Still Photographer |
| Jean-Philippe Berubé | Video Assist Operator |
| Eames Gagnon | Gaffer |
| Toby Bronson | Set Costumer |
| Monica Haynes | Set Costumer |
| Jennifer Dunnington | Music Editor |
| Denny Caira | Transportation Coordinator |
| Robin Citrin | Location Manager |
| Céline Daignault | Location Manager |
| Martha Pinson | Script Supervisor |
| Tim Monich | Dialect Coach |
| Larry Kaplan | Unit Publicist |
| Chris Brigham | Executive Producer |
| Colin Cotter | Executive Producer |
| Matthias Deyle | Producer |
| Leonardo DiCaprio | Executive Producer |
| Dan Maag | Line Producer |
| Aslan Nadery | Executive Producer |
| Joseph P. Reidy | Co-Producer |
| Volker Schauz | Executive Producer |
| Philip Schulz-Deyle | Line Producer |
| Rick Schwartz | Executive Producer |
| Bob Weinstein | Executive Producer |
| Harvey Weinstein | Executive Producer |
| Rick Yorn | Executive Producer |
| Martin Scorsese | Executive Producer |
| Cydney Cornell | Hairstylist |
| Carolyn Elias | Key Hair Stylist |
| David Davenport | Costume Supervisor |
| Randall Poster | Music Supervisor |
| Tom Foligno | First Assistant Editor |
| Scott Brock | First Assistant Editor |
| Genevieve Ferderber | Art Department Assistant |
| Leigh-Alexandra Jacob | Lead Painter |
| Annie Godin | Line Producer |
| Lori A. Balton | Location Scout |
| Jimmy Garcia | Painter |
| Tim Ackers | Standby Painter |
| Dana Gonzales | Additional Camera |
| Tim Arasheben | Camera Technician |
| Herb Ault | Key Grip |
| Marjorie McCown | Assistant Costume Designer |
| Kathryn Blondell | Hair Department Head |
| Duncan Jarman | Prosthetic Makeup Artist |
| Paul Hotte | Set Dressing Artist |
| Carrie Wilksen | Set Dressing Supervisor |
| Colin Dennis | Carpenter |
| H. Leah Amir | Craft Service |
| Danny Braet | Digital Effects Supervisor |
| Gina August | Driver |
| Melanie Banders | Loader |
| Tyler W. Gaisford | Picture Car Coordinator |
| Angela Beresford | Post Production Assistant |
| Alison Cannon | Production Controller |
| Michael Crowe | Propmaker |
| Joe Rystrom | Set Medic |
| Aaron C. Fitzgerald | Set Production Assistant |
| Reuben Pasquini | Software Engineer |
| Cynthia Beckert | Stand In |
| Jan Foster | Unit Production Manager |
| John Trujillo | Layout |
| Stéphane Byl | Electrician |
| John R. Manocchia | Rigging Gaffer |
| Jennifer Euston | Casting Associate |
| Alison Harstedt | Production Accountant |
| Danielle Boucher | Production Coordinator |
| Carl Fischer | Boom Operator |
| Chris Fielder | Assistant Sound Editor |
| Eugene Gearty | Sound Designer |
| Petur Hliddal | Sound Mixer |
| Pepe Valencia | Animation Supervisor |
| Matthew Collorafice | Digital Compositors |
| R. Bruce Steinheimer | Special Effects Supervisor |
| Kevin Field | Visual Effects Coordinator |
| Grady Campbell | Sequence Leads |
| Jack Stern | Studio Teachers |
| Robert Spurlock | Mechanical Designer |
| Jim Kontos | Unit Manager |
| Fred Rosenberg | Dialogue Editor |
| Laura Civiello | Dialogue Editor |
| Nicholas Renbeck | Dialogue Editor |
| Hope M. Parrish | Property Master |
| Kenton Jakub | ADR Editor |
| Hal Levinsohn | ADR Editor |
| Joseph P. Reidy | First Assistant Director |
| Kam Chan | Foley Editor |
| Steven Visscher | Foley Editor |
| Jacob Ribicoff | Foley Editor |
| Peter Dress | Second Second Assistant Director |
| Dan Perri | Title Designer |
| Tahira Herold | Assistant Makeup Artist |
| Martine Gagnon | Costume Assistant |
| Cynthia Black | Costumer |
| Cookie Lopez | Dresser |
| Julie Amyot | Extras Dresser |
| Emilie Gauthier | Extras Makeup Artist |
| Jean-Jacques Dion | Hairdresser |
| Kenn Smiley | Key Costumer |
| Simon Rose | Prosthetic Makeup Artist |
| Vernon Davidson | Additional Second Assistant Director |
| Fabrice Barrilliet | Additional Third Assistant Director |
| Christopher Surgent | Second Assistant Director |
| Robert Legato | Second Unit Director |
| Geneviéve Duguay | Third Assistant Director |
| Cathy Scorsese | Assistant Property Master |
| Jose Fernando Varela | Assistant Set Dresser |
| Ray Légaré | Head Greensman |
| Ann Knight | Set Buyer |
| Jocelyn Clouàtre | Swing |
| Michael Miller | ADR Mixer |
| David Boulton | ADR Recordist |
| Marko Costanzo | Foley Artist |
| George A. Lara | Foley Mixer |
| Phillip Fuller | Sound Mix Technician |
| Marissa Littlefield | Supervising ADR Editor |
| Jacques Belair | Special Effects Technician |
| Gerardo Ortiz | Visual Effects Assistant Editor |
| A.J. Raitano | Visual Effects Camera |
| David E. Franks | Visual Effects Compositor |
| Grant Anderson | Visual Effects Technical Director |
| Allan Padelford | Stunt Driver |
| Jennifer Ann Henry | Additional Second Assistant Camera |
| Juliet Verni | Assistant Camera |
| Christian Bertrand | Best Boy Grip |
| Renee Olsen | Camera Production Assistant |
| Doug Chartier | Dolly Grip |
| David H. Kramer | ADR Voice Casting |
| Meghan Rafferty | Casting Assistant |
| Julie Alexandra Lepage | Wardrobe Assistant |
| Blanche Boileau | Wardrobe Supervisor |
| Erin Crackel | Assistant Editor |
| Nicolae Ilies | Colorist |
| Paul McGhee | Digital Color Timer |
| Ron Barr | Digital Intermediate Editor |
| Stephanie Ito | Digital Intermediate Producer |
| Stuart Macphee | Post Production Coordinator |
| Denis Paquette | Assistant Location Manager |
| Tom Roberts | Music Arranger |
| Jim Dunbar | Music Coordinator |
| Stewart Lerman | Music Producer |
| Carole J. Guignard | Administrative Assistant |
| Craig Hosking | Aerial Coordinator |
| Raymond Ducasse | Animal Coordinator |
| Tony Buccola | Art Department Production Assistant |
| Mark Hadland | Assistant Chief Lighting Technician |
| Izabela Krawczynska | Assistant Craft Service |
| Guylaine Boucher | Assistant Production Coordinator |
| Frederik Joly | Assistant Unit Manager |
| Allen Lewonski | CG Artist |
| Ian Kincaid | Chief Lighting Technician |
| Paul Graff | Compositing Supervisor |
| Jonathan Stone | Digital Effects Producer |
| David Greenbaum | Executive Assistant |
| Gerrard Coffey | First Assistant Accountant |
| John Gendron | Head Driver |
| Claude Fortin | Key Rigging Grip |
| Steve Riley | Key Special Effects |
| Simone Perusse | Lighting Programmer |
| Dylan Cole | Matte Painter |
| Bill Hempel | Pilot |
| Daniela De Carlo | Production Assistant |
| Jeff Barnes | Production Executive |
| Sue Smith | Production Secretary |
| Richard Stutsman | Pyrotechnic Supervisor |
| Chuck Hessey | Pyrotechnician |
| Marianne Bower | Researcher |
| Cynthia Aragon | Rotoscoping Artist |
| Gino Falla | Second Assistant Accountant |
| Michel Leduc | Security Coordinator |
| Adriana Poblano | Travel Coordinator |
| Shirley Dolle | Additional Hairstylist |
| Carol Pershing | Additional Hairstylist |
| Audrey L. Anzures | Assistant Hairstylist |
| Martin Lapointe | Hairdresser |
| Réjean Forget | Key Hair Stylist |
| Tina Harrelson | Key Makeup Artist |
| Colleen Quinton | Key Makeup Artist |
| Greg Nelson | Makeup Artist |
| Ric Sagliani | Makeup Artist |
| Erin Wooldridge | Makeup Artist |
| Michelle Vittone | Makeup Artist |
| Vasilios Tanis | Makeup Artist |
| Sian Grigg | Makeup Artist |
| Gregor Tavenner | First Assistant "A" Camera |
| Jamie Felz | First Assistant "B" Camera |
| Martin Lebel | First Assistant "B" Camera |
| Mikey Bertrand | Key Grip |
| Martin St-Antoine | Key Rigging Grip |
| Nicolas Venne | Rigging Gaffer |
| Eric Leach | Rigging Grip |
| Kelly Uchimura | Second Assistant Camera |
| Claude Beauchamp | Second Assistant "A" Camera |
| Chloé Giroux-LaChance | Second Assistant "B" Camera |
| Philip C. Pfeiffer | Second Unit Director of Photography |
| Annie Pomerleau | Art Department Assistant |
| Kurt Leitner | Art Department Production Assistant |
| Lori Rowbotham | Assistant Art Director |
| Isabelle Côté | Graphic Designer |
| Peter G. Travers | Digital Effects Supervisor |
| Jonathan Stone | Digital Effects Producer |
| Don Lee | Visual Effects Compositor |
| Tami Goldsmith | Visual Effects Coordinator |
| Matthew A. Rubin | Visual Effects Coordinator |
| Bonjin Byun | Visual Effects Technical Director |
| Fish Essenfeld | Visual Effects Technical Director |
| George Ho | Visual Effects Technical Director |
| Dave R. Howe | Visual Effects Technical Director |
| Blaine Kennison | Visual Effects Technical Director |
| Jonathan Litt | Visual Effects Technical Director |
| Sarah M. Sweeney | Visual Effects Technical Director |
| Amanda Morrison | Visual Effects Technical Director |
| Winston Quitasol | Visual Effects Technical Director |
| Victor Schutz | Visual Effects Technical Director |
| Eric Tablada | Visual Effects Technical Director |
| Eliza Coleman | Stunts |
| Doug Coleman | Stunt Coordinator |
| Matthew Dickens | Choreographer |
| Donna Keegan | Stunts |
| Keith Campbell | Stunts |
| Hélèna Laliberté | Stunts |
| Joey Box | Stunts |
