 | Tim Blake Nelson als Buster Scruggs (segment "The Ballad of Buster Scruggs") |
 | Willie Watson als The Kid (segment "The Ballad of Buster Scruggs") |
 | Clancy Brown als Curly Joe (segment "The Ballad of Buster Scruggs") |
 | Danny McCarthy als Curly Joe's Brother (segment "The Ballad of Buster Scruggs") |
 | David Krumholtz als Frenchman (segment "The Ballad of Buster Scruggs") |
 | Thomas Wingate als Gun Check Man (segment "The Ballad of Buster Scruggs") |
 | Tim DeZarn als Mean-Eyed Card Player (segment "The Ballad of Buster Scruggs") |
 | E.E. Bell als Piano Player (segment "The Ballad of Buster Scruggs") |
 | Alejandro Patiño als Cantina Bartender (segment "The Ballad of Buster Scruggs") |
 | Tom Proctor als Cantina Bad Man (segment "The Ballad of Buster Scruggs") |
| Clinton Roberts als Cantina Scum (segment "The Ballad of Buster Scruggs") |
 | Matthew Willig als Cantina Scum (segment "The Ballad of Buster Scruggs") |
| Jesse Youngblood als Cantina Scum (segment "The Ballad of Buster Scruggs") |
 | J.J. Dashnaw als Cantina Scum (segment "The Ballad of Buster Scruggs") |
 | James Franco als Cowboy (segment "Near Algodones") |
 | Stephen Root als Teller (segment "Near Algodones") |
 | Ralph Ineson als Posse Leader (segment "Near Algodones") |
 | Mike Watson als Posse (segment "Near Algodones") |
| Brian Brown als Posse (segment "Near Algodones") |
 | Ryan Brown als Posse (segment "Near Algodones") |
| Richard Bucher als Posse (segment "Near Algodones") |
 | Jesse Luken als Drover (segment "Near Algodones") |
 | Michael Cullen als Judge (segment "Near Algodones") |
 | Austin Rising als Bailiff (segment "Near Algodones") |
| James 'Scotty' Augare als Comanche Chief (segment "Near Algodones") |
 | Liam Neeson als Impresario (segment "Meal Ticket") |
 | Harry Melling als Artist (segment "Meal Ticket") |
 | Jiji Hise als The Bawd (segment "Meal Ticket") |
 | Paul Rae als Chicken Impresario (segment "Meal Ticket") |
 | Tom Waits als Prospector (segment "All Gold Canyon") |
 | Sam Dillon als Young Man (segment "All Gold Canyon") |
 | Bill Heck als Billy Knapp (segment "The Gal Who Got Rattled") |
 | Zoe Kazan als Alice Longabaugh (segment "The Gal Who Got Rattled") |
 | Grainger Hines als Mr. Arthur (segment "The Gal Who Got Rattled") |
 | Jefferson Mays als Gilbert Longabaugh (segment "The Gal Who Got Rattled") |
| Prudence Wright Holmes als Boarding House Landlady (segment "The Gal Who Got Rattled") |
 | Eric Petersen als Boarder (segment "The Gal Who Got Rattled") |
| Doris Hargrave als Boarder (segment "The Gal Who Got Rattled") |
| Jackamoe Buzzell als Boarder (segment "The Gal Who Got Rattled") |
| Ethan Dubin als Matt (segment "The Gal Who Got Rattled") |
| Jordy Laucomer als Whipped Boy (segment "The Gal Who Got Rattled") |
| Thea Lux als His Mother (segment "The Gal Who Got Rattled") |
| Bret Hughson als His Father (segment "The Gal Who Got Rattled") |
| Rod Rondeaux als Sioux Chief (segment "The Gal Who Got Rattled") |
 | Raymond Kurshals als Puppet Dancer (segment "The Gal Who Got Rattled") |
 | Jonjo O'Neill als Englishman (segment "The Mortal Remains") |
 | Brendan Gleeson als Irishman (segment "The Mortal Remains") |
 | Saul Rubinek als Frenchman (segment "The Mortal Remains") |
 | Tyne Daly als Lady (segment "The Mortal Remains") |
 | Chelcie Ross als Trapper (segment "The Mortal Remains") |
 | Martin Palmer als Blubberer (segment "Near Algodones") (uncredited) |
 | Billy Lockwood als Father (segment "The Gal Who Got Rattled") (uncredited) |
 | Katy Bodenhamer als Milkmaid (segment "The Gal Who Got Rattled) (uncredited) |
| Stephen R. Estler als Gambler (segment "The Ballad of Buster Scruggs") (uncredited) |
| Grace LeSueur als Pretty Girl at Gallows (segment "Near Algodones") (uncredited) |
 | Bill Foster als Saloon Man (segment "The Ballad of Buster Scruggs") (uncredited) |
| Joel Coen | Director |
| Joel Coen | Screenplay |
| Joel Coen | Producer |
| Ethan Coen | Director |
| Ethan Coen | Screenplay |
| Ethan Coen | Producer |
| Joel Coen | Editor |
| Ethan Coen | Editor |
| Megan Ellison | Producer |
| Jess Gonchor | Production Design |
| Nancy Haigh | Set Decoration |
| Mary Zophres | Costume Designer |
| Sue Naegle | Producer |
| Carter Burwell | Original Music Composer |
| Bruno Delbonnel | Director of Photography |
| Ellen Chenoweth | Casting |
| Stephen Christensen | Art Direction |
| Cydney Cornell | Hair Department Head |
| Andreya Joseph | Hairstylist |
| K-Bobby | Hairstylist |
| Rolf John Keppler | Key Makeup Artist |
| Christien Tinsley | Makeup Department Head |
| Sheila Trujillo-Gomez | Makeup Artist |
| Corey Welk | Key Makeup Artist |
| Catherine Farrell | Post Production Supervisor |
| Karen Ruth Getchell | Production Manager |
| Zack Earl Edwards | Additional Second Assistant Director |
| David Tierney Lerner | Additional Second Assistant Director |
| Kevin Lumley | Second Assistant Director |
| Jeremy Reisig | Second Second Assistant Director |
| Paul Schmitz | Second Assistant Director |
| Zack Smith | Second Second Assistant Director |
| Davi Aquino | Foley Recordist |
| Craig Berkey | Supervising Sound Editor |
| Chelsea Body | Foley Recordist |
| Brian Bowles | Dialogue Editor |
| Nicholas Cochran | Sound Re-Recording Mixer |
| Blake Collins | ADR Mixer |
| Kelly Doran | Sound |
| Michael Feuser | Supervising Dialogue Editor |
| Matthew Haasch | Foley Editor |
| Randall L. Johnson | Boom Operator |
| Matthew Kay | Foley Mixer |
| Goro Koyama | Foley Artist |
| Peter F. Kurland | Sound Mixer |
| Andy Malcolm | Foley Artist |
| Igor Nikolic | Foley Supervisor |
| Greg Orloff | Sound Re-Recording Mixer |
| Wyatt Sprague | Foley Editor |
| Caleb Townsend | Assistant Sound Editor |
| Roderic Duff | Special Effects Technician |
| David Greene | Special Effects Technician |
| Jack London | Author |
| Stewart Edward White | Author |
| Skip Lievsay | Sound Re-Recording Mixer |
| Skip Lievsay | Supervising Sound Editor |
| Craig Berkey | Sound Re-Recording Mixer |
| Lucian Johnston | First Assistant Editor |
| Zack Gonchor | Assistant Art Director |
| Chris Farmer | Supervising Art Director |
| Gretchen Bright | Makeup Artist |
| Bonnie Masoner | Makeup Artist |
| Lance Cheatham | Set Dresser |
| Marisa Frantz | Set Designer |
| Jonathan Lheureux | Set Dresser |
| Richard Anthony Montoya | Set Dresser |
| Adam Mull | Set Designer |
| Chris Painter | Set Dresser |
| Greg Papalia | Set Designer |
| Alexis Pearlman-Flores | Set Dresser |
| Sara Philpott | Assistant Set Decoration |
| Siobhan Roome | Set Designer |
| John Bair | Visual Effects Supervisor |
| Leslie Chung | Visual Effects Supervisor |
| Julian Dimsey | Visual Effects Producer |
| Rebecca Dunn | Visual Effects Producer |
| Robin Scott Graham | Visual Effects Supervisor |
| John Kilshaw | Visual Effects Supervisor |
| Alex Lemke | Visual Effects Supervisor |
| Nathan Overstrom | Visual Effects Supervisor |
| Ron Pogue | Visual Effects Producer |
| Josh Simmonds | Visual Effects Supervisor |
| Mark Avery | Set Costumer |
| Lynda Foote | Costume Supervisor |
| Jennifer Gingery | Set Costumer |
| Brittnee Holmquist | Set Costumer |
| Robin Myriah Hatcher | Special Effects Makeup Artist |
| Bruno Delbonnel | "A" Camera Operator |
| Andy Harris | First Assistant Camera |
| Joshua Gollish | Digital Imaging Technician |
| Artu Arin | Second Assistant "A" Camera |
| Paul Elliott | "B" Camera Operator |
| Liza Bambenek | First Assistant "B" Camera |
| Arlen Cooke | First Assistant "B" Camera |
| Alison Cohen Rosa | Still Photographer |
| Lobsang Tenzin | Camera Loader |
| Betsy Magruder | First Assistant Director |
| Rachel Manera | Set Painter |
