 | Steve Martin als Stu Preissler |
 | Jack Black als Brad Harris |
 | Owen Wilson als Kenny Bostick |
 | Brian Dennehy als Raymond Harris |
 | Anjelica Huston als Annie Auklet |
 | Rashida Jones als Ellie |
 | Rosamund Pike als Jessica |
 | Dianne Wiest als Brenda Harris |
 | JoBeth Williams als Edith |
 | Anthony Anderson als Bill Clemont |
 | Corbin Bernsen als Gil Gordon |
 | Barry Shabaka Henley als Dr. Neil Kramer |
 | Joel McHale als Barry Loomis |
 | Tim Blake Nelson als Fuchs |
 | Jim Parsons als Crane |
 | Kevin Pollak als Jim Gittelson |
 | Nate Torrence als Ted Simkin |
 | Steven Weber als Rick |
 | Zahf Paroo als Prasad |
 | John Cleese als Historical Montage Narrator (voice) |
 | Paul Campbell als Tony |
 | Cindy Busby als Susie |
 | Greg Kean als Computer Birder |
 | Eva Bourne als Birder's Daughter |
 | Bill Dow als Dr. Paul Elkin |
 | June Squibb als Old Lady |
 | Craig Bockhorn als Lawyer |
 | Joey Aresco als Frank Falucci |
 | Ryan Caltagirone als Frank Jr. |
 | Al Roker als New York Weatherman |
 | Christopher Mann als Security Guard |
 | Jan Bos als Local Newsman (High Island) |
 | Kate Gajdosik als Local Newswoman (High Island) |
 | William Samples als British Tourist |
 | Scott Patey als Birder (High Island) |
 | Marci T. House als Troop Leader |
 | Michael Bean als Waiter |
 | Christopher Redman als Scott |
 | Devon Weigel als Karen |
 | Andrew Wilson als Mike Shin |
 | Gabrielle Rose als Mary Swit |
 | Calum Worthy als Colin Debs |
| Doreen Ramus als CB Announcer |
 | Terence Kelly als Pete Shackelford |
| Steve Darling als Anchorage Weatherman |
| Jon Frankel als Anchorage Anchorman |
 | David Lewis als Lanky Birder |
 | Jesse Moss als Darren |
| Kath Dugray als Motel Manager |
 | Morgan Brayton als Ferry Ticket Seller |
 | Sheelah Megill als Nurse |
 | Veena Sood als Nurse Katie |
 | Dee Jay Jackson als Parking Attendant |
| Calvin Lee als Chinese Waiter |
| Tshering Garie als Chinese Waitress |
 | Michael Karl Richards als Vicki's Fiancée (uncredited) |
 | Stacey Scowley als Vicki (uncredited) |
| Curtis Hanson | Producer |
| Carol Fenelon | Executive Producer |
| Howard Franklin | Screenplay |
| David Frankel | Director |
| Karen Rosenfelt | Producer |
| Theodore Shapiro | Original Music Composer |
| Mark Livolsi | Editor |
| Patty York | Makeup Artist |
| Heike Brandstatter | Casting |
| Coreen Mayrs | Casting |
| Lawrence Sher | Director of Photography |
| Margery Simkin | Casting |
| Ben Stiller | Executive Producer |
| Monique Prudhomme | Costume Design |
| Michael Diner | Art Direction |
| Stuart Cornfeld | Producer |
| Lisa Love | Makeup Artist |
| Lisa Love | Makeup Department Head |
| Joseph A. Campayno | Makeup Artist |
| Jeremy Kramer | Executive Producer |
| Brad Van Arragon | Co-Producer |
| David Lucarelli | ADR Recordist |
| Charleen Richards | ADR Mixer |
| Todd Scott | Stunts |
| Greg Beaton | First Assistant "B" Camera |
| Peter Lando | Set Decoration |
| Jeffrey Harlacker | Associate Producer |
| Marko Costanzo | Foley Artist |
| Wyatt Sprague | Sound Effects Editor |
| Nicholas Renbeck | Supervising Dialogue Editor |
| Ed Anders | Stunt Coordinator |
| Julia Michels | Music Supervisor |
| Byron Brisco | Stunts |
| Mike Carpenter | Stunts |
| Mike Crestejo | Stunts |
| Scott J. Ateah | Stunt Coordinator |
| Brent Woolsey | Stunts |
| Brent Thomas | Production Design |
| Paul Tirone | Sound Re-Recording Mixer |
| Laurel Bergman | Assistant Art Director |
| George A. Lara | Foley Mixer |
| Lori West | Graphic Designer |
| Owen Walstrom | Stunts |
| Janene Carleton | Stunts |
| Ryan Ennis | Stunts |
| Rich Brown | Payroll Accountant |
| Martina Javorova | Art Direction |
| David Dowling | Property Master |
| Dan DiPrima | Supervising Music Editor |
| David Clarke | Assistant Art Director |
| Rino Pace | Location Manager |
| Douglas Murray | ADR Mixer |
| Murray Close | Still Photographer |
| Trig Singer | "C" Camera Operator |
| John Clothier | Steadicam Operator |
| John Clothier | "A" Camera Operator |
| Patricia Barry | Assistant Production Coordinator |
| Susan Lambie | Script Supervisor |
| John Dekker | Gaffer |
| Sylvia Nablo | Transportation Coordinator |
| Tom Fleischman | Sound Re-Recording Mixer |
| Jesse Joslin | Construction Coordinator |
| Eric J. Robertson | Visual Effects Supervisor |
| Debra Wiebe | Hairstylist |
| Debra Wiebe | Hair Department Head |
| Kenton Jakub | ADR Editor |
| Bob Chefalas | Sound Re-Recording Mixer |
| Lorraine Jamison | Unit Publicist |
| Sean M. Harding | First Assistant "B" Camera |
| Scott Nicholson | Stunts |
| Andrew D. Wilson | "B" Camera Operator |
| Celia Bond | Stunts |
| Andrea Simpson | Assistant Hairstylist |
| Alex Burdett | Special Effects Coordinator |
| Thierry Tanguy | Location Manager |
| David Rogow | Additional Editor |
| Geraldine Jones | Hairstylist |
| Leah Ehman | Assistant Makeup Artist |
| Lawrence Zipf | Assistant Sound Editor |
| Paul Urmson | Supervising Sound Editor |
| Sean Goojha | Art Department Coordinator |
| Thomas S. Drescher | Music Editor |
| Randy Kerber | Orchestrator |
| Rick Chefalas | First Assistant Sound Editor |
| Steven Visscher | Foley Supervisor |
| Pete Anthony | Orchestrator |
| Pete Anthony | Conductor |
| Amy Nygaard | Casting Associate |
| David Husby | Production Sound Mixer |
| William Kruzykowski | First Assistant Editor |
| Laura Lee Connery | Stunts |
| Michael Mayo | Rigging Gaffer |
| Charles O'Shea | Boom Operator |
| Mike Marsten | Set Dresser |
| Mark Aisbett | Stunts |
| Jimmy Waitman | Stunts |
| Wes Hamby | Assistant Property Master |
| Summer Eves | Truck Costumer |
| J. Michael Williams | Unit Production Manager |
| Susan Crawford | Production Coordinator |
| Keith McCulloch | Construction Foreman |
| Justine Hempe | Casting Associate |
| Gil Forrester | Dolly Grip |
| Mark Bunting | Second Assistant Director |
| Spencer Louttit | Assistant Property Master |
| Rob Dampier | Construction Foreman |
| Darian Deering | Set Dresser |
| Kim Olsen | Key Grip |
| Cliff Brown | Transportation Captain |
| Jason Miller | Post Production Coordinator |
| Jim Brebner | First Assistant Director |
| Paul Lavigne | Costume Set Supervisor |
| Leif Havdale | Stunts |
| Julie Donovan | First Assistant "A" Camera |
| Bryce Shaw | Grip |
| Troy James Sobotka | Grip |
| Curt Griebel | Rigging Grip |
| Jennifer Grossman | Costume Coordinator |
| Lucas Comstock | Set Costumer |
| Debera Barager | Production Accountant |
| Dave Campbell | Stunts |
| Bert Prevost | Transportation Co-Captain |
| Michael Fowler | ADR Recordist |
| Karen Pelrine | Assistant Production Coordinator |
| Daniel DiPrima | Supervising Music Editor |
| Scott Calderwood | Assistant Set Decoration |
| Richard Sinclair | Second Assistant "A" Camera |
| Jared Krenz | Camera Trainee |
| Andrew Capicik | Second Assistant "B" Camera |
| Carrie Wilson | Second Assistant "C" Camera |
| Brent Bennett | Set Decoration Buyer |
| Lise Hache | Assistant Costume Designer |
| James Forsyth | Extras Casting |
| Guy Miller | Set Dresser |
| Dan Gorval | Best Boy Grip |
| David Lourie | First Assistant "C" Camera |
| Jason Collier | Assistant Location Manager |
| Scott Cozens | Camera Loader |
| Curt Bonn | Stunts |
| Dan Kuzmenko | Assistant Location Manager |
| Eric Potter | Sound Recordist |
| Jacques Larrue | Set Dresser |
| Mark Obmascik | Book |
| Sonia Gemmiti | Art Department Assistant |
| Don Vargas | Costumer |
| Andrew Mackie | Rigging Grip |
| Aaron Wik | Grip |
| Michael Gazetas | Location Manager |
| Corine Buffel | Production Coordinator |
| Laura Obenaus | Casting Assistant |
| Kim Duess | Stunts |
| Ty Trand | Stunt Double |
| Gregory Wise | Stunts |
| Shandy Lashley | Visual Effects Coordinator |
| Craig Jones | Best Boy Electric |
| Heather Osborne | Costumer |
| Marc Borja | Assistant Accountant |
| Beaux Neylon | ADR Mixer |
| Paul Frye | ADR Recordist |
