 | Nate Parker als Nat Turner |
 | Armie Hammer als Samuel Turner |
 | Aja Naomi King als Cherry |
 | Jackie Earle Haley als Raymond Cobb |
 | Penelope Ann Miller als Elizabeth Turner |
 | Gabrielle Union als Esther |
 | Mark Boone Junior als Reverend Zalthall |
 | Aunjanue Ellis-Taylor als Nancy Turner |
 | Dwight Henry als Isaac Turner |
 | Esther Scott als Bridget Turner |
 | Roger Guenveur Smith als Isaiah |
 | Jeryl Prescott als Janice |
 | Colman Domingo als Hark |
 | Dominic Bogart als Hank Fowler |
 | Jason Stuart als Joseph Randall |
 | Katie Garfield als Catherine Turner |
 | Jayson Warner Smith als Earl Fowler |
 | Steve Coulter als General Childs |
 | Aiden Flowers als Young John Clarke |
 | Dane Davenport als John Clarke Turner |
 | Chiké Okonkwo als Will |
 | Tony Espinosa als Young Nat Turner |
 | Kai Norris als Jasper |
 | Chris Greene als Nelson |
 | Kelvin Harrison Jr. als Simon |
 | Justin Randell Brooke als Guiles Reese |
 | Ryan Mulkay als Jesse |
| Allen Phoenix als Abner |
| Vincent Anthony als Fowler Slave |
| Bobby Batson als Little boy |
| Damon Bellmon als Turner Hideaway |
| Gregory Black als Rebel Slave |
 | Alkoya Brunson als Young Hark |
| Anthony Bryant als Rebel Slave |
| Victoria Budkey als Lynch Mob |
 | Sheila Cochran als General Child's Wife |
 | Logan Coffey als Son |
| Kemuel Crossty als Rebel Man |
 | Nicole Davis als Angel (uncredited) |
| Morgen Dukes als Kid |
| Shannon Edwards als Farmer (uncredited) |
 | Brad Schmidt als Lieutenant Akers |
| Nate Parker | Director |
| Steven Rosenblum | Editor |
| Jean McGianni Celestin | Story |
| Henry Jackman | Original Music Composer |
| Elliot Davis | Director of Photography |
| Mary Vernieu | Casting |
| Michelle Wade Byrd | Casting |
| Geoffrey Kirkland | Production Design |
| James Edward Ferrell Jr. | Set Decoration |
| Francine Jamison-Tanchuck | Costume Design |
| Jason Michael Berman | Producer |
| Aaron L. Gilbert | Producer |
| Preston L. Holmes | Producer |
| Nate Parker | Producer |
| Kevin Turen | Producer |
| Mac Smith | Supervising Sound Editor |
| Michael Novogratz | Executive Producer |
| Heikki Kossi | Foley Artist |
| Matthew Lindner | Co-Producer |
| Nate Parker | Story |
| Nate Parker | Screenplay |
| David S. Goyer | Executive Producer |
| Michael Finley | Executive Producer |
| Tony Parker | Executive Producer |
| Jason Cloth | Executive Producer |
| Andrew Pollack | Executive Producer |
| Allan J. Stitt | Executive Producer |
| Jane Oster Sinisi | Executive Producer |
| Barb Lee | Executive Producer |
| Carl H. Lindner III | Executive Producer |
| Derrick Brooks | Executive Producer |
| Jill Ahrens | Executive Producer |
| Ryan Ahrens | Executive Producer |
| Armin Tehrany | Executive Producer |
| Edward Zwick | Executive Producer |
| Mark Moran | Executive Producer |
| John Raymonds | Co-Executive Producer |
| Brenda Gilbert | Co-Executive Producer |
| Steven Thibault | Co-Executive Producer |
| Lori Massini | Co-Executive Producer |
| Zak Tanjeloff | Co-Producer |
| Harrison Kreiss | Co-Producer |
| Ike Waldhaus | Co-Producer |
| Ben Renzo | Co-Producer |
| George Loucas | Visual Effects Supervisor |
| Mark Moran | Unit Production Manager |
| Tomas Deckaj | First Assistant Director |
| Mark C. Stevens | Second Assistant Director |
| Andrea Craven | Extras Casting |
| Lisa Mae Fincannon | Local Casting |
| Lavonna Cupid | Local Casting |
| Craig Fincannon | Local Casting |
| Andrea Hume | Extras Casting |
| Greg Lockett | Extras Casting |
| Jack Ballance | Art Direction |
| Sonya Duvall | Art Department Coordinator |
| Sarah Myers | Set Decoration Buyer |
| Craig Henighan | Sound Re-Recording Mixer |
| Craig Henighan | Supervising Sound Editor |
