 | Sid Haig als Captain Spaulding / James Cutter |
 | Bill Moseley als Otis B. Driftwood |
 | Sheri Moon Zombie als Baby Firefly / Vera-Ellen |
 | William Forsythe als Sheriff John Quincy Wydel |
 | Ken Foree als Charlie Altamont |
 | Matthew McGrory als Tiny Firefly |
 | Leslie Easterbrook als Mother Firefly |
 | Geoffrey Lewis als Roy Sullivan |
 | Priscilla Barnes als Gloria Sullivan |
 | Dave Sheridan als Officer Ray Dobson |
 | Kate Norby als Wendy Banjo |
 | Lew Temple als Adam Banjo |
 | Danny Trejo als Rondo |
 | Page Falkinburg Jr. als Billy Ray Snapper |
 | Elizabeth Daily als Candy |
 | Tom Towles als Lieutenant George Wydell |
 | Michael Berryman als Clevon |
 | P.J. Soles als Susan |
 | Deborah Van Valkenburgh als Casey |
 | Ginger Lynn Allen als Fanny |
 | Mary Woronov als Abbie |
 | Daniel Roebuck als Morris Green |
 | Duane Whitaker als Dr. Bankhead |
 | Steve Railsback als Sheriff Ken Dwyer |
 | Tyler Mane als Rufus |
 | Brian Posehn als Jimmy |
 | Michael 'Red Bone' Alcott als Darrell |
 | Chris Ellis als Coggs |
 | Kane Hodder als Officer with Gas Mask (uncredited) |
 | Jessica Helmer als Otis' Victim (uncredited) |
| Monika Mikkelsen | Casting |
| Michael Ohoven | Producer |
| Brent Morris | Co-Producer |
| Cole S. McKay | Stunts |
| Robert Kurtzman | Visual Effects Supervisor |
| Anthony Tremblay | Production Design |
| Tyler Bates | Music |
| John Hartigan | Special Effects Coordinator |
| Rob Zombie | Screenplay |
| Rob Zombie | Director |
| Rob Zombie | Producer |
| Mike Elliott | Producer |
| Andy Gould | Producer |
| Marco Mehlitz | Producer |
| Phil Parmet | Director of Photography |
| Glenn Garland | Editor |
| T.K. Kirkpatrick | Art Direction |
| Lisa Tong | Set Decoration |
| Yasmine Abraham | Costume Design |
| Kane Hodder | Stunt Coordinator |
| Rosine 'Ace' Hatem | Stunts |
| David Daniel | Camera Operator |
| Merritt Yohnka | Stunts |
| Gary J. Wayton | Stunts |
| Joe Cappelletti | ADR Voice Casting |
| Patrick Cyccone Jr. | Sound Re-Recording Mixer |
| Wayne Toth | Special Effects Makeup Artist |
| Rick Davidson | Steadicam Operator |
| Douglas Noe | Makeup Artist |
| Paul E. Short | Stunt Double |
| Perry Robertson | Supervising Sound Editor |
| Barney Cabral | Supervising Sound Editor |
| Adam Jenkins | Sound Re-Recording Mixer |
| Geno Hart | Transportation Coordinator |
| Gene Page | Still Photographer |
| Walter Volpatto | Digital Intermediate |
| Cynthia Merrill | Foley Artist |
| John Trapman | Camera Operator |
| Chris Hayes | Camera Operator |
| Michael Diersing | Construction Coordinator |
| John Nicolard | Digital Intermediate |
| Maria Sandoval | Hairstylist |
| Abigail Sheiner | Art Department Coordinator |
| Robert W. Anderson | Property Master |
| Treven Bedwell | Leadman |
| Patrick Cabral | Foley Artist |
| Scott Sanders | Sound Designer |
| Georgiana Ramsland | Music Editor |
| Sandy Schklair | Script Supervisor |
| George McDowell Agnew | Location Manager |
| Laura Howell | Unit Publicist |
