 | Jennifer Aniston als Justine Last |
 | John C. Reilly als Phil Last |
 | Jake Gyllenhaal als Holden Worther |
 | Zooey Deschanel als Cheryl |
 | Deborah Rush als Gwen Jackson |
 | Mike White als Corny |
 | John Carroll Lynch als Jack Field, Your Store Manager |
 | Tim Blake Nelson als Bubba |
 | John Doe als Mr. Worther |
 | Roxanne Hart als Mrs. Worther |
 | Aimee Garcia als Nurse |
 | Annie O'Donnell als Haggard Woman |
 | Jon Shere als Lester |
 | Alice Amter als Big Haired Woman |
| Jean Rhodes als Old Woman |
| Lalo Guerrero als Blackberry Vendor |
 | Michael Hyatt als Floberta |
| Enzo als Bits |
 | Ken Rudulph als Reporter |
 | Jacquie Barnbrook als Heavy Set Woman |
| Carol Baum | Executive Producer |
| Miguel Arteta | Director |
| Tony Maxwell | Original Music Composer |
| Matthew Greenfield | Producer |
| Philip von Alvensleben | Executive Producer |
| Enrique Chediak | Director of Photography |
| Joey Waronker | Original Music Composer |
| Kirk D'Amico | Executive Producer |
| James O'Brien | Original Music Composer |
| Joanna Colbert | Casting |
| Jeff Betancourt | Editor |
| Mark Orton | Original Music Composer |
| Susan Emshwiller | Set Decoration |
| Nancy Steiner | Costume Design |
| Macie Vener | Art Direction |
| Daniel Bradford | Production Design |
| Lucas Foster | Thanks |
| Shelly Glasser | Co-Producer |
| Gina Kwon | Co-Producer |
| Robert Jauregui | Stunts |
| Shelly Glasser | Unit Production Manager |
| Linda Brachman | First Assistant Director |
| Marge Piane | Second Assistant Director |
| Bradley M. Goodman | Post Production Supervisor |
| Steven Kaminsky | Post Production Supervisor |
| Margaret Yen | Music Supervisor |
| Andrew Loschin | First Assistant Editor |
| Christopher Coulson | Leadman |
| Gabor Szitanyi | Set Dresser |
| Gretchen Engel | Art Department Coordinator |
| Darin Moran | Camera Operator |
| Robert Magnano | First Assistant Camera |
| Kelly Krotine | Second Assistant Camera |
| Christianne Kira Parser | Second Assistant Camera |
| Rusty Geller | Steadicam Operator |
| Colin Anderson | Steadicam Operator |
| Randy Nolen | Steadicam Operator |
| Dale Robinette | Still Photographer |
| Yehuda Maayan | Sound Mixer |
| Dan Lipe | Boom Operator |
| Leslie Silvey | Production Coordinator |
| Damiana Kamishin | Assistant Production Coordinator |
| William S. White | Production Secretary |
| John Riley | Second Second Assistant Director |
| Jeff Bilger | Second Second Assistant Director |
| Rebecca Fulton | Script Supervisor |
| Petra Jorgensen | Script Supervisor |
| Louis DiCesare | Chief Lighting Technician |
| Tim Durr | Best Boy Electric |
| Kevin P. Patterson | Electrician |
| Moulaye Sene | Electrician |
| Pierre Cane | Electrician |
| Lloyd Moriarity | Key Grip |
| Charles 'Woody' Lang | Best Boy Grip |
| Tom Adams | Dolly Grip |
| John Emory | Grip |
| Bobby D. Bartlett | Grip |
| Dave Harvey | Grip |
| William Christie | Grip |
| Michael Carney | Property Master |
| Derrick Hinman | Assistant Property Master |
| Carol Schwartz | Key Makeup Artist |
| Darla Albright | Assistant Makeup Artist |
| Daniel Curet | Key Hair Stylist |
| Ken Scaife | Construction Coordinator |
| Frank B. Nieves | Construction Foreman |
| Joe Lozano | Greensman |
| B.J. Rogers | Costume Supervisor |
| Chris Burrows | Costume Supervisor |
| Christie Wittenborn | Key Costumer |
| France Myung Fagin | Location Manager |
| Charles Fagin | Assistant Location Manager |
| Meredith Tucker | Casting |
| Jeff Olan | Extras Casting |
| Peter McManus | Production Accountant |
| Robert Yacobian | First Assistant Accountant |
| Wendy Wilhite Chatley | Studio Teacher |
| Charmaine Boos | Studio Teacher |
| Francie Agajanian | Studio Teacher |
| Joy Ellison | Dialect Coach |
| Francie Brown | Dialect Coach |
| Steve M. Miliotti | Craft Service |
| Michael Merrick | Transportation Coordinator |
| Steve Zerweck | Transportation Captain |
| Russ Tolliver | Transportation Co-Captain |
| David Waine | Special Effects Coordinator |
| Christopher Sheldon | Supervising Sound Editor |
| Dane A. Davis | Supervising Sound Editor |
| Wayne Heitman | Sound Re-Recording Mixer |
| Chris David | Sound Re-Recording Mixer |
| Eddie Kim | Sound Effects Designer |
| Stephanie Flack | Dialogue Editor |
| Christopher Alba | First Assistant Sound Editor |
| Lana Warnock | Assistant Sound Editor |
| Eryne Prine | Assistant Sound Editor |
| John Roesch | Foley Artist |
| Alyson Dee Moore | Foley Artist |
| Marilyn Graf | Foley Mixer |
| Carolyn Tapp | Foley Recordist |
| Matthew C. Beville | ADR Mixer |
| Stephen Lotwis | Music Editor |
| Peter Afterman | Music Consultant |
| Joey Waronker | Music Consultant |
| Jessica Clements | Music Coordinator |
| Dennis McNeill | Color Timer |
| Mike White | Writer |
