 | Anjelica Huston als Lilly Dillon |
 | John Cusack als Roy Dillon |
 | Annette Bening als Myra Langtry |
 | Jan Munroe als Guy in bar |
 | Robert Weems als Racetrack Announcer |
 | Stephen Tobolowsky als Jeweler |
 | Jimmy Noonan als Bartender |
 | Richard Holden als Cop |
 | Henry Jones als Sims |
 | Michael Laskin als Irv |
 | Eddie Jones als Mintz |
 | Sandy Baron als Doctor |
 | Lou Hancock als Nurse |
 | Gailard Sartain als Joe |
| Noelle Harling als Nurse Carol Flynn |
 | Ivette Soler als Maid |
 | Pat Hingle als Bobo Justus |
 | Paul Adelstein als Sailor - Young Paul |
 | Jeremy Piven als Sailor - Freshman |
 | Gregory Sporleder als Sailor - Spooney |
| David Sinaiko als Sailor - Stinky |
 | Jeff Perry als Drunk |
 | Jon Gries als Drunk's Friend |
 | Micole Mercurio als Waitress |
 | Charles Napier als Gloucester Hebbing |
 | J.T. Walsh als Cole |
| Teresa Gilmore als Receptionist 1 |
| Elizabeth Ann Feeley als Receptionist 2 |
 | Billy Ray Sharkey als FBI man |
 | Frances Bay als Arizona Motel Clerk |
 | Xander Berkeley als Lt. Pierson |
 | Steve Buscemi als Kaggs (uncredited) |
| John Gillespie als Bartender (uncredited) |
 | Juliet Landau als Young Lilly (uncredited) |
 | Sy Richardson als Cab Driver (uncredited) |
 | Martin Scorsese als Opening voice-over (uncredited) |
| Jim Thompson | Novel |
| Stephen Frears | Director |
| Donald E. Westlake | Screenplay |
| Mick Audsley | Editor |
| Elmer Bernstein | Original Music Composer |
| Oliver Stapleton | Director of Photography |
| Peggy Rajski | Co-Producer |
| Martin Scorsese | Producer |
| Barbara De Fina | Executive Producer |
| Robert A. Harris | Producer |
| Jim Painter | Producer |
| Dennis Gassner | Production Design |
| Richard Hornung | Costume Design |
| Juliet Taylor | Casting |
| Victoria Thomas | Casting |
| Llewellyn Wells | Production Manager |
| J. Stephen Buck | First Assistant Director |
| Joe Camp III | Second Assistant Director |
| Leslie McDonald | Art Direction |
| Nancy Haigh | Set Decoration |
| Richard Davis, Jr. | Location Manager |
| Mary Cybulski | Script Supervisor |
| John Sutton | Sound Mixer |
| Ian Wright | Boom Operator |
| Julie Hewett | Makeup Artist |
| Cydney Cornell | Hairstylist |
| Kathleen M. Courtney | Production Coordinator |
| Beth Bernstein | Assistant Production Coordinator |
| Cynthia Quan | Production Accountant |
| Marco Mazzei | First Assistant Camera |
| Katherine M. Butler | Second Assistant Camera |
| Matthew Morrissey | Third Assistant Camera |
| Suzanne Hanover | Still Photographer |
| Kant Pan | Supervising Sound Editor |
| Peter Maxwell | Sound Re-Recording Mixer |
| Derek Holding | Dialogue Editor |
| Rick Dunford | Foley Editor |
| Douglas Fox | Property Master |
| Bill Cancienne | Assistant Property Master |
| Joseph Timothy Conway | Assistant Property Master |
| Jody Hummer | Assistant Location Manager |
| Scott Plauche | Art Department Coordinator |
| Paige Augustine | Assistant Set Decoration |
| Claire Gaul | Assistant Set Decoration |
| Robert Greenfield | Leadman |
| Mark Bridges | Assistant Costume Designer |
| Kimberly Adams | Assistant Costume Designer |
| Elizabeth Feldbauer | Wardrobe Supervisor |
| Jack English | Gaffer |
| James Babineaux | Best Boy Electric |
| Gary Jensen | Stunt Coordinator |
| Frank Viviano | Construction Coordinator |
| Chris Snyder | Construction Foreman |
| A. Welch Lambeth | Transportation Coordinator |
| Bill M. Puluti | Transportation Captain |
| Jory Weitz | Casting Associate |
