 | Pete Davidson als Scott Carlin |
 | Marisa Tomei als Margie Carlin |
 | Bill Burr als Ray Bishop |
 | Bel Powley als Kelsey |
 | Maude Apatow als Claire Carlin |
 | Steve Buscemi als Papa |
 | Pamela Adlon als Gina |
 | Action Bronson als Shot or Stabbed Victim |
 | Kevin Corrigan als Joe |
 | Ricky Velez als Oscar |
 | Moisés Arias als Igor |
 | Lou Wilson als Richie |
 | Carly Aquilino als Tara |
 | Robert Vidal III als Jimmy Bags' Brother |
 | Angus Costello als Kid Who Vomits |
 | Pauline Chalamet als Joanne |
 | Lynne Koplitz als Joy |
 | Joseph Paul Kennedy als Todd |
 | Nina Hellman als Joanne's Mother |
| Jack Hamblin als Joanne's Father |
| Stephen Davidson als Grandpa |
 | Keith Robinson als Security Guard |
 | Luke David Blumm als Harold |
 | Liza Treyger als Waitress at Denino's |
 | Derek Gaines als Zoots |
 | Meredith Handerhan als Woman Eating in Restaurant |
 | Rich Vos als Husband Ordering in Restaurant |
 | Bonnie McFarlane als Wife Ordering in Restaurant |
| Jay Rodriguez als Pepe |
 | Jimmy Tatro als Firefighter Savage |
| Giselle King als Firefighter Jaylen Patterson |
| John Sorrentino als Captain Palazzo |
 | Alexis Rae Forlenza als Kelly |
 | Domenick Lombardozzi als Firefighter Lockwood |
| Rafael Poueriet als Firefighter Morales |
 | Nana Mensah als Kindergarten Teacher |
 | Machine Gun Kelly als Tattoo Shop Owner |
| Kill als Tattoo Customer |
 | Anthony Lee Medina als Kelsey's Tinder Date |
| Nyla Durdin als Beautiful Girl at Bar |
| Katherine Ray Zimmerman als Young Winona Ryder |
 | Lilly Brown als Girl in Dorm Room |
 | Robert Smigel als Male Pharmacy Owner |
 | Jessica Kirson als Female Pharmacy Owner |
 | Laurence Blum als First Cop at Pharmacy |
 | David S. Lomax als Second Cop at Pharmacy |
| Casey Davidson als Carla |
| Antony Marino als Dougie |
| Nils Johnson als Man Yelling in Backyard |
 | Mario Polit als Firefighter Rivera |
 | Mike Vecchione als Firefighter Thompson |
 | Hank Strong als Firefighter Gardner |
 | Marilyn Torres als Admissions Nurse in ER |
 | Teodorina Bello als Patient in Pain in ER |
 | Michelle Sohn als Doctor in ER |
 | Ken Holmes als Patient (uncredited) |
| Emma R. Mudd als Classroom Student (uncredited) |
| Melania Zalipsky als School Kid (uncredited) |
 | Gina Jun als Baseball Fan |
 | Adam Keane als Bar Patron |
| Judd Apatow | Director |
| Judd Apatow | Producer |
| Barry Mendel | Producer |
| Michael Bederman | Executive Producer |
| Pete Davidson | Writer |
| Dave Sirus | Writer |
| Judd Apatow | Writer |
| Robert Elswit | Director of Photography |
| William Kerr | Editor |
| Brian Scott Olds | Editor |
| Pete Davidson | Executive Producer |
| Judah Miller | Executive Producer |
| Dave Sirus | Co-Producer |
| Ricky Velez | Co-Producer |
| Michael Andrews | Original Music Composer |
| Jay Cassidy | Editor |
| Gayle Keller | Casting |
| David Rubin | Casting |
| Kevin Thompson | Production Design |
| Nick Francone | Art Direction |
| David Schlesinger | Set Decoration |
| Sarah Mae Burton | Costume Design |
| Michael J. Braun | Hairstylist |
| Adam Cummins | Hairstylist |
| Louise McCarthy | Makeup Department Head |
| Jill McKay | Key Makeup Artist |
| Dennis Polanco | Key Hair Stylist |
| Vincent Schicchi | Makeup Artist |
| Jeremy Selenfriend | Makeup Artist |
| Kerrie Smith | Hair Department Head |
| Jen Malone | Music Supervisor |
| Fam Udeorji | Music Supervisor |
| Michael Bederman | Unit Production Manager |
| H.H. Cooper | First Assistant Director |
| Eddie Griffith | Second Assistant Director |
| Manny Siverio | Stunt Coordinator |
| Peter Wallack | Stunt Double |
| Paul Nandzik | Stunt Double |
| James S. Gonzalez | Stunt Double |
| Leo Gutman | Stunt Double |
| Scottio Arnold | Stunt Double |
| Ricky Barksdale | Stunt Double |
| Mark Pettograsso | Stunt Double |
| Steve Rizzo | Stunt Double |
| Charley Brucato | Stunts |
| Mike Burke | Stunts |
| Chris Colombo | Stunts |
| Stracy Diaz | Stunts |
| Owen Holland | Stunts |
| Gina Limbrick | Stunts |
| Roberto Lopez | Stunts |
| Michael Matera | Stunts |
| John McEnerney | Stunts |
| Josiah Nolan | Stunts |
| Bob Roseman | Stunts |
| Elliot Santiago | Stunts |
| David Shumbris | Stunts |
| Stephanie Vovou | Stunts |
| Scott Gallopo | Associate Producer |
| Amanda Glaze | Associate Producer |
| Michael Lewen | Associate Producer |
| Leigh Pruden | Associate Producer |
| Craig Herring | Additional Editor |
| Angelica Borrero-Fortier | Assistant Art Director |
| Jen Price Fick | Assistant Art Director |
| Mary Attaway | Assistant Set Decoration |
| Martin Lasowitz | Property Master |
| Anna Weber | Art Department Coordinator |
| Truman Clark McCasland | Art Department Coordinator |
| Abariss Culjak | Assistant Property Master |
| Kimberly A. Fleming | Assistant Property Master |
| Harvey Goldberg | Leadman |
| Romano C. Pugliese | Set Dresser |
| Malicky Reilly | Set Dresser |
| Seth Finkin | Set Dresser |
| Gerard Sava | Steadicam Operator |
| Gerard Sava | "B" Camera Operator |
| Stephen Consentino | "B" Camera Operator |
| Stephen Consentino | Steadicam Operator |
| Robert Lau | First Assistant "A" Camera |
| Sarah Guenther | Second Assistant "A" Camera |
| Samantha Panger | Second Assistant "B" Camera |
| Rory Hanrahan | First Assistant "B" Camera |
| Graham Burt | First Assistant "B" Camera |
| Bill Almeida | Gaffer |
| Clay Liversidge | Rigging Gaffer |
| Charles R. Hunt | Production Sound Mixer |
| Thomas W. Jordan | Boom Operator |
| Charlie Marroquin | Key Grip |
| Nick Haines-Stiles | Best Boy Grip |
| Holly Hosman | Grip |
| Chris Cochran | Grip |
| Kelly Marroquin | Grip |
| Andrew Sweeney | Dolly Grip |
| John Krause | Dolly Grip |
| Caleb P. Johnson | Special Effects Coordinator |
| Allison Cirbus | Assistant Costume Designer |
| Willa Piro | Assistant Costume Designer |
| Cristina Spiridakis | Assistant Costume Designer |
| Robin Fitzgerald | Costume Supervisor |
| Nicole Capogna | Set Costumer |
| Steffi West Harshberger | Set Costumer |
| Yafi Hoch | Set Costumer |
| Jessica Harmston | Set Costumer |
| Thomas Johnston | Script Supervisor |
| Mia Thoen | Makeup Artist |
| Bobby Mackston | Supervising Sound Editor |
| Joel Dougherty | Sound Re-Recording Mixer |
| Sean Garnhart | Sound Re-Recording Mixer |
| David 'Gus' Gustafson | Production Supervisor |
| John DeSimone | Production Coordinator |
| Ashleigh Tucker | Assistant Production Coordinator |
| Amy Leigh Johnson | Unit Publicist |
| Joan Altman | Production Accountant |
| Allison Kirschner | Casting Associate |
| Matt Lander | Casting Associate |
| Briana Dunlay | Casting Assistant |
| Brittany N. Williams | Casting Assistant |
| Grant Wilfley | Background Casting Director |
| Kevin Flynn | Transportation Captain |
| Peter Kreinbihl | Transportation Co-Captain |
| Kenneth Marsten | First Assistant Editor |
| Yoni Rusnak | Assistant Editor |
| Erin Oakley | ADR Supervisor |
| Robert Troy | Dialogue Editor |
| Jon Wakeham | Dialogue Editor |
| Sean Garnhart | Sound Effects Editor |
| Norm MacLeod | Assistant Sound Editor |
| Vincent Guisetti | Foley Artist |
| Aran Tanchum | Foley Mixer |
| Aaron Hasson | ADR Mixer |
| Ashley Lambert | ADR Voice Casting |
| Ranjani Brow | ADR Voice Casting |
| Ryan Castle | Music Editor |
| Lou Gatti | Visual Effects Coordinator |
