 | Keanu Reeves als Alex Wyler |
 | Sandra Bullock als Kate Forster |
 | Christopher Plummer als Simon Wyler |
 | Ebon Moss-Bachrach als Henry Wyler |
 | Willeke van Ammelrooy als Kate's Mother |
 | Dylan Walsh als Morgan |
 | Shohreh Aghdashloo als Anna Klyczynski |
 | Lynn Collins als Mona |
 | Mike Bacarella als Mulhern |
 | Kevin M. Brennan als Waiter |
 | Frank Caeti als Cove Patron |
 | Aliyah Carr als Girl Patient |
| Jennifer Clark als Nurse Practitioner |
 | Jacob D. Dumelle als Patient on Gurney |
| Scott Elias als Doug |
 | Lori Ann Gerdisch als I.C.U. Nurse |
 | Cynthia Kaye McWilliams als Vanessa Vanderbeck |
 | India Neilan als Hostess |
 | Mia Park als Receptionist |
 | Jacqueline Williams als Madhvi Patel |
 | Peggy Roeder als Attendant |
 | Jason Wells als Costello |
 | Tiffini Funches als Young Nurse |
 | Jennifer Kern als Nurse |
 | Michael Andrew Gorman als Cove Bartender |
| Bruce Berman | Executive Producer |
| Lynzee Klingman | Editor |
| Rachel Portman | Original Music Composer |
| David Carbonara | Music Editor |
| Meg Everist | Set Decoration |
| Erwin Stoff | Executive Producer |
| Josh McLaglen | First Assistant Director |
| Deena Appel | Costume Design |
| Nathan Crowley | Production Design |
| Kevin Kavanaugh | Art Direction |
| Alejandro Agresti | Director |
| David Auburn | Screenplay |
| Kim Eun-jeong | Screenplay |
| Yeoh Gee-na | Screenplay |
| Doug Davison | Producer |
| Roy Lee | Producer |
| Alar Kivilo | Director of Photography |
| Alejandro Brodersohn | Editor |
| Dana Goldberg | Executive Producer |
| Mary McLaglen | Executive Producer |
| Tobiasz Daszkiewicz | Stunts |
| Dominic Mango | Hair Department Head |
| Tom Lowell | Stunts |
| Carl Paoli | Stunts |
| Sonny Mallhi | Co-Producer |
| Katherine Quittner | Music Editor |
| Suzi Ostos | Makeup Department Head |
| Rick LeFevour | Stunts |
| Rick LeFevour | Stunt Coordinator |
| Daniel Maldonado | Stunts |
| Brian Christensen | Stunts |
| Sherry Gallarneau | Script Supervisor |
| Peter Sorel | Still Photographer |
| Mark La Bonge | Steadicam Operator |
| Janine Rath | Hairstylist |
| Chris Mulsoff | Rigging Gaffer |
| Nina Paskowitz | Hairstylist |
| Pamela S. Westmore | Makeup Artist |
| John Houlihan | Music Supervisor |
| Geri B. Oppenheim | Makeup Artist |
| Frank P. Calzavara | Stunts |
| James Fierro | Stunts |
| Natalie M. Meyer | Stunts |
| Makiko Carlson | First Assistant Camera |
| Linda Perlin | Stunts |
| James Mammoser | Stunts |
| Kevin Sorensen | Stunts |
| Alicia Skirball | Stunts |
| Mark Harper | Stunts |
| Scott Philyaw | Stunts |
| Melanie A. Allen | Stunts |
| Jodi Starnes | Stunts |
| Maryann Kelman | Stunts |
