 | Adam Sandler als Danny Meyerowitz |
 | Ben Stiller als Matthew Meyerowitz |
 | Dustin Hoffman als Harold Meyerowitz |
 | Emma Thompson als Maureen Meyerowitz |
 | Elizabeth Marvel als Jean Meyerowitz |
 | Grace Van Patten als Eliza Meyerowitz |
 | Candice Bergen als Julia Meyerowitz |
 | Adam Driver als Randy |
 | Judd Hirsch als L.J. Shapiro |
 | Rebecca Miller als Loretta Shapiro |
 | Matthew Shear als Gabe |
 | Danny Flaherty als Marcus |
 | Adam David Thompson als Brian |
 | Ronald Peet als James |
 | Hannah Mitchell als MOMA Employee |
 | Sigourney Weaver als Sigourney Weaver |
 | David Cromer als Glenn Twitchell |
| James Hamilton als MOMA Guest |
 | Josh Hamilton als Loretta's Friend |
 | Gibson Frazier als Ma'itre d' |
 | Jordan Carlos als Waiter |
 | Benjamin Thys als European Man |
 | Lyne Renee als European Woman |
 | Sakina Jaffrey als Dr. Malini Soni |
 | Gayle Rankin als Pam |
 | Michael Chernus als Male Nurse |
 | Cindy Cheung als Nurse #1 |
| Mandy Siegfried als Nurse #2 |
 | Victor Cruz als Doctor (ICU) |
 | Joel Bernstein als Doctor (End of Life) |
| Jerry Matz als Paul Epstein |
 | Germar Terrell Gardner als Paul's Nurse |
 | Mickey Sumner als Woman at Bard |
| Justin Winley als Robin |
| Kareem Williams als Nurse's Aide |
 | Carlos Jacott als Town Car Driver |
| Nico Baumbach als Whitney Employee |
 | McManus Woodend als Gary |
 | Annabelle Dexter-Jones als Gallery Girl |
 | Marquis Rodriguez als College Kid #1 |
 | Jared Sandler als College Kid #2 |
| Michael Birnberg als Restaurant Patron |
| Jason Daunno als Guy at the Gallery |
| Teniel Humeston als Gallery Girl |
| Barbara Danicka als Gallery Marchant |
 | Greta Gerwig als Victoria (voice) |
| Jake Perlin als Jake |
 | Hannah Elizabeth Alexander als MOMA Guest |
 | Jarrett Winters Morley als Bard Student |
| Patrick Donohue | Grip |
| Noah Baumbach | Director |
| Jennifer Lame | Editor |
| Noah Baumbach | Writer |
| Robbie Ryan | Director of Photography |
| Scott Rudin | Producer |
| Valerie Velez | Key Hair Stylist |
| Karen Kane | First Assistant Director |
| Mike Drury | Assistant Property Master |
| Gerald Sullivan | Production Design |
| Nicolas Locke | Art Direction |
| Ann Pala | Key Makeup Artist |
| Catherine Farrell | Post Production Supervisor |
| Ulises Rodríguez | Production Supervisor |
| Lila Yacoub | Unit Production Manager |
| Francine Maisler | Casting |
| Jason Miller | Art Department Coordinator |
| Matt Lake | Second Assistant Director |
| Patrick Head | Property Master |
| Eli Bush | Producer |
| Jason Sack | Co-Producer |
| Joseph G. Aulisi | Set Decoration |
| Noah Baumbach | Producer |
| Lila Yacoub | Producer |
| Kris Moran | Set Decoration |
| Georgina Marquis | Unit Production Manager |
| Nancy Nieves | Hairstylist |
| Richard Hebrank | Construction Coordinator |
| Douglas Aibel | Casting |
| Jim Bauer | Set Dresser |
| Tom Molinelli | Key Makeup Artist |
| Ed Joseph | Set Dresser |
| Wellington Lee | Location Scout |
| Thomas Beauter | Driver |
| Boughen Clinton | Driver |
| Timothy Paustian | Transportation Captain |
| Mike Rhodes | Driver |
| Cristian Gallon | Electrician |
| Atsushi Nishijima | Still Photographer |
| Jason Velez | Gaffer |
| Zachary A. Schwartz | First Assistant Editor |
| Danielle Smith | Key Costumer |
| Vince Camuto Sr. | Boom Operator |
| Jeff Brink | Special Effects Coordinator |
| Vincent Lanza | Grip |
| Scott Sousa | Grip |
| Alyssa Bracken | Costume Coordinator |
| Jessica Chaney | Set Costumer |
| Daniel Torres | Electrician |
| Ryan Smith | Location Manager |
| Larry Hoover | Driver |
| Greg Miller | Driver |
| Billy Brennan | Set Production Assistant |
| Peter Scheck | Leadman |
| Robert Bowman | Grip |
| Henry Russell Bergstein | Casting Associate |
| Lucian Johnston | Assistant Editor |
| Ray Van Ness | Driver |
| Mike Brown | Set Production Assistant |
| Joseph Wood | Driver |
| Clarke Woolven | Driver |
| Emily Aragones | Set Production Assistant |
| Manny Siverio | Stunt Coordinator |
| Spencer Rubin | Grip |
| Kevin Draves | Wardrobe Supervisor |
| Robin Monaghan | Driver |
| Connell Burke | Electrician |
| Thomas Jirgal | Dolly Grip |
| Elizabeth Kirby | Assistant Costume Designer |
| Mickey Pastoriza | Transportation Co-Captain |
| Renato Quiridumbay | Best Boy Electric |
| Mitchell Travers | Assistant Costume Designer |
| Mike Alboro | Driver |
| Chris Moone | Camera Operator |
| Mike Quigley | Rigging Gaffer |
| Kathleen Mohler | Casting Associate |
| Ed Boyle | Driver |
| Mike Cella | Driver |
| Ken Ishii | Sound Mixer |
| Steven Visscher | Foley Editor |
| Jess Magee | Location Scout |
| George Holtzer | Driver |
| Rob Leary | Driver |
| Stanley Fernandez Jr. | First Assistant Camera |
| Mike Yurich | Key Grip |
| Jennifer Stimple Kamei | Set Costumer |
| Joseph W. Kelly | Driver |
| Edward Marquette | Driver |
| Bob Spitzfaden | Driver |
| Randy Newman | Original Music Composer |
| George Drakoulias | Music Supervisor |
| Paul Hsu | Sound Re-Recording Mixer |
| Joseph G. Aulisi | Costume Design |
| Noyan Cosarer | Sound Re-Recording Mixer |
| Ken Ishii | Production Sound Mixer |
| Alessio Masi | Sound Re-Recording Mixer |
| Sara Stern | Sound Editor |
| Dave Flynch | Sound Editor |
| Sean Perry | VFX Artist |
| Judy Chin | Makeup Department Head |
| Bernadette Mazur | Makeup Artist |
| Ann Pala | Makeup Artist |
| Nathanael Brotherhood | Special Effects |
| Jeff Kryvicky | Main Title Designer |
