 | Naomi Watts als Rachel Keller |
 | Simon Baker als Max Rourke |
 | David Dorfman als Aidan Keller |
 | Elizabeth Perkins als Dr. Emma Temple |
 | Ryan Merriman als Jake |
 | Sissy Spacek als Evelyn |
 | Gary Cole als Martin Savide |
 | Emily VanCamp als Emily |
 | Mary Elizabeth Winstead als Young Evelyn |
 | Kelly Overton als Betsy |
 | James Lesure als Doctor |
 | Daveigh Chase als Samara (archive footage) |
 | Kelly Stables als Evil Samara |
 | Cooper Thornton als Father of Emily |
 | Jesse Burch als Male Reporter |
 | Chane't Johnson als Adoption Counselor |
 | Marilyn McIntyre als Mother of Emily |
 | Mary Joy als Sister Elizabeth |
| Chris Bender | Co-Executive Producer |
| Walter F. Parkes | Producer |
| Deborah Aquila | Casting |
| Neal Edelstein | Co-Executive Producer |
| Christa Munro | Art Direction |
| Ehren Kruger | Screenplay |
| Laurie MacDonald | Producer |
| Dennie Thorpe | Foley Artist |
| James D. Bissell | Production Design |
| Peter Chesney | Special Effects Coordinator |
| Neil A. Machlis | Executive Producer |
| Debbie Zoller | Makeup Department Head |
| Tami Treadwell | ADR Recordist |
| Lauri Gaffin | Set Decoration |
| Keith Campbell | Stunt Coordinator |
| Gabriel Beristain | Director of Photography |
| Michael N. Knue | Editor |
| J.C. Spink | Co-Executive Producer |
| Roy Lee | Executive Producer |
| Henning Lohner | Original Music Composer |
| Hideo Nakata | Director |
| Kôji Suzuki | Novel |
| Wendy Chuck | Costume Design |
| Jane Oshita | Stunts |
| Martin Tillman | Original Music Composer |
| Michele Imperato | Unit Production Manager |
| Michele Imperato | Co-Producer |
| Jennifer L. Smith | Casting Associate |
| Tim Gomillion | Sound Recordist |
| Bonnie Morgan | Stunts |
| Mike Macari | Executive Producer |
| Mark Vargo | Second Unit Cinematographer |
| Mel Friedman | First Assistant Editor |
| Michele Weisler | Executive Producer |
| Mark Graziano | Post Production Supervisor |
| Deborah Ricketts | Researcher |
| Danny Eccleston | Gaffer |
| George Simpson | Supervising Sound Editor |
| Brad Martin | Stunts |
| John Brian King | Title Designer |
| Daniel W. Barringer | Stunts |
| Bruce Fowler | Orchestrator |
| Dylan Cole | Visual Effects Art Director |
| Tricia Wood | Casting |
| Jeffrey A. Cook | Electrician |
| Jesse Cook | Researcher |
| Ashton Moio | Stunt Double |
| Cosmas A. Demetriou | Set Designer |
| Randy L. Childs | Propmaker |
| Donald Flick | Sound Effects Editor |
| Lee Wimer | Color Timer |
| Nathan McGuinness | Senior Visual Effects Supervisor |
| Trudy Ramirez | Script Supervisor |
| Tony Bonaventura | Property Master |
| John T. Cucci | Foley |
| Ethan van der Ryn | Sound Designer |
| Bob Newlan | Dialogue Editor |
| James M. Churchman | Stunts |
| Zachary Fannin | Art Department Production Assistant |
| Jamie Kemp | Chef |
| Paul C. Babin | Camera Operator |
| Daniel Pinder | Music Editor |
| Ned R. Shapiro | Location Manager |
| Nicole Randall | Stunt Double |
| Cosmas Paul Bolger Jr. | Visual Effects Producer |
| Kristopher Kasper | Visual Effects Editor |
| Zeke Morales | Visual Effects Editor |
| Craig Fikse | Steadicam Operator |
| Alex L. Worman | Unit Publicist |
| Natasha Ladek | Wigmaker |
| Matthew C. Blea | Second Assistant Camera |
| Glenn E. Moran | Rigging Gaffer |
| Joel Román Mendías | Production Executive |
| Curtis A. Andrews Jr. | Lighting Technician |
| David Diamond | Assistant Location Manager |
| Thad Beier | Technical Supervisor |
| Nava R. Sadan | Costume Supervisor |
| Charles Gibson | Second Unit Director |
| Steve Baker | CG Animator |
| Bill McAdams Jr. | Stand In |
| Fiachra Trench | Conductor |
| Jeannine Bourdaghs | Set Costumer |
| Karen Higgins | Construction Coordinator |
| Francesco Franco Ferrara | Painter |
| John Moio | Stunts |
| Gemma La Mana | Still Photographer |
| Keith Roberts | Animation Supervisor |
| Bob Skemp | Greensman |
| Mark Rodahl | Digital Effects Supervisor |
| Heather Ignarro | Visual Effects Coordinator |
| John S. Campbell | Grip |
| Robert Morrisey | Assistant Sound Editor |
| Larry J. Aube | Key Rigging Grip |
| Michael Axinn | ADR Editor |
| Glenn Corbett | Assistant Chief Lighting Technician |
| Julie Helton | Loader |
| Doug Metzger | First Assistant Director |
| Nico Bally | Dolly Grip |
| Whitney Kitchen | 3D Coordinator |
| Travis Crenshaw | Foley Recordist |
| Dan Cayer | Digital Compositor |
| Michael Alexonis | Best Boy Grip |
| Robert West | Production Coordinator |
| David MacMillan | Production Sound Mixer |
| Becky Bentham | Music Coordinator |
| Frank 'Pepe' Merel | Foley Mixer |
| Anthony Carlino | Leadman |
| Lea Anderson | Craft Service |
| Alan Cohen | First Assistant Camera |
| Jason Bayever | Lighting Supervisor |
| John 'J.P.' Pratt | Picture Car Coordinator |
| Michael C. Price | Key Grip |
| Robert K. Johnson | Transportation Captain |
| Jamie Rama | Production Illustrator |
| Trevor Goring | Storyboard Artist |
| Gary Burritt | Negative Cutter |
| Chris Romberg | Assistant Accountant |
| Harrison D. Marsh | Boom Operator |
| Chris Paizis | Matchmove Supervisor |
| Craig Cannold | Production Supervisor |
| Keli Murphy | Stunt Double |
| Matthew J. Barden | Rigging Grip |
| Thomas Garris | Driver |
| Ara Soudjian | Art Department Assistant |
| Susan Chooljian | Art Department Coordinator |
| Dianne Darcy | Hairstylist |
| E. Larry Day | Makeup Artist |
| Brady J. Condit | Set Dresser |
| Dustin Brown | Post Production Assistant |
| Ann Penny | Set Medic |
| Ken C. Wu | Set Production Assistant |
| Brian Corpus | Software Engineer |
| Kenny Searle | Transportation Coordinator |
| Richard Scarpone | Video Assist Operator |
| Jack Ford | Sound Engineer |
| Dan Akers | Digital Compositors |
| Fatima Mojaddidy | I/O Supervisor |
| Serge Riou | Digital Producer |
| Michael Hansen | Assistant Property Master |
| Frederic Roth | Second Assistant Director |
| Robert Ferrara | Chief Lighting Technician |
| Orlando R. Gonzales | Assistant Production Coordinator |
| Matthew A. Del Ruth | Assistant Camera |
| Rick Newsome | Storyboard Designer |
| Jiřina Eisenhamerová | Costumer |
| Paul Leonard | Stunts |
| David Santiago | CG Artist |
| William Aldridge | Special Effects Technician |
| Sven E. Fahlgren | Post Production Coordinator |
| Deborah Thomas | Data Wrangler |
| Giselle Gurza | Second Second Assistant Director |
| Craig Doobie | Best Boy Grip |
| Zach Justman | Assistant Editor |
| Teresa Jaime Drapkin | Payroll Accountant |
| Chandra Irving | Production Assistant |
| Afnahn Khan | Production Secretary |
| Jennifer Koenig | Second Assistant Accountant |
| Kurt Zelnak | Travel Coordinator |
| Casey Easlick | Stunt Double |
| Michael Anthony Jackson | Storyboard Artist |
