 | Gene Hackman als Royal Tenenbaum |
 | Anjelica Huston als Etheline Tenenbaum |
 | Gwyneth Paltrow als Margot Helen Tenenbaum |
 | Ben Stiller als Chassie Tenenbaum |
 | Luke Wilson als Richie Tenenbaum |
 | Owen Wilson als Eli Cash |
 | Bill Murray als Raleigh St. Clair |
 | Danny Glover als Henry Sherman |
 | Kumar Pallana als Pagoda |
 | Stephen Lea Sheppard als Dudley Heinsbergen |
 | Grant Rosenmeyer als Ari Tenenbaum |
| Jonah Meyerson als Uzi Tenenbaum |
 | Seymour Cassel als Dusty |
 | Alec Baldwin als Narrator (voice) |
| Aram Aslanian-Persico als Young Chas Tenenbaum |
 | Irina Gorovaia als Young Margot Tenenbaum |
| Amedeo Turturro als Young Richie Tenenbaum |
| James Fitzgerald als Young Eli Cash |
 | Larry Pine als Peter Bradley |
| Don McKinnon als Detective |
 | Frank Wood als Hotel Manager |
 | Al Thompson als Walter Sherman |
| Jennifer Wachtell als Rachael Tenenbaum |
| Donal Lardner Ward als Hotel Clerk |
 | Andrew Wilson als Farmer Father / Tex Hayward |
 | Dipak Pallana als Doctor |
| Sanjay Mathew als Sanjay Gandhi |
| Mary Wigmore als Chas' Secretary |
 | Sonam Wangmo als Sing-Sang |
| Gita Gabriel als Facialist |
| Pawel Wdowczak als Neville Smythe-Dorleac |
| Peter Leung als Yasuo Oshima |
| William Sturgis als Franklin Benedict |
 | Liam Craig als Reporter in Blue Cardigan |
 | Ebon Moss-Bachrach als Frederick - Bellboy |
| Sheelagh Tellerday als Eli's Aunt |
| Max Faugno als Cote d'Ivoire Attendant |
 | Guido Venitucci als Cote d'Ivoire Radio Operator |
 | Brian Smiar als Elderly 'Baumer' Fan #1 |
| Jan Austell als Elderly 'Baumer' Fan #2 |
| Rony Clanton als Cemetery Maintenance Man |
| Salim Malik als Anwar |
| Tom Lacy als Judge |
| Keith Charles als Royal's Lawyer |
 | Greg Goossen als Gypsy Cab Driver |
 | Saidah Arrika Ekulona als Nurse |
| Vic Mata als Sanchez |
| Michael Conti als Irish Longshoreman |
| Tatiana Abbey als Parisian Girl |
 | Kalani Queypo als New Guinea Tribesman |
| Mel Cannon als Punk Rocker |
| Leo Manuelian als Eli's Egyptian Friend |
| Amir Raissi als Eli's Egyptian Friend |
| Roger Shamas als Eli's Egyptian Friend |
| Philip Denning als Father Petersen |
 | Rex Robbins als Mr. Levinson |
| Nova Landaeus-Skinnar als Elaine Levinson |
| Sam Hoffman als Paramedic |
 | Brian Tenenbaum als Paramedic |
 | Stephen Dignan als Paramedic |
 | Eric Chase Anderson als Medical Student |
| Gary Evans als Police Officer |
 | Wes Anderson als Tennis Match Commentator #1 (voice) (uncredited) |
| Owen Wilson | Executive Producer |
| Owen Wilson | Writer |
| Dylan Tichenor | Editor |
| David Wasco | Production Design |
| Scott Rudin | Producer |
| Mark Berger | Sound Re-Recording Mixer |
| Rudd Simmons | Executive Producer |
| David Boulton | ADR Mixer |
| Wes Anderson | Director |
| Wes Anderson | Producer |
| Wes Anderson | Writer |
| Barry Mendel | Producer |
| Mark Mothersbaugh | Original Music Composer |
| Robert D. Yeoman | Director of Photography |
| Douglas Aibel | Casting |
| Sandy Reynolds-Wasco | Set Decoration |
| David M. Dunlap | Camera Operator |
| Robert Hein | Supervising Sound Editor |
| Magdaline Volaitis | Sound Effects Editor |
| Randall Balsmeyer | Visual Effects Supervisor |
| Adam Scher | Assistant Art Director |
| Brian Vancho | Foley Artist |
| Karen Patch | Costume Design |
| Sharon Globerson | Assistant Costume Designer |
| Randall Poster | Music Supervisor |
| Sam Hoffman | First Assistant Director |
| Judy Dickerson | Dialect Coach |
| Todd Milner | Foley Editor |
| Denise Pinckley | Unit Production Manager |
| Scott Rosenstock | Leadman |
| Cindy Tolan | Casting Associate |
| Michael Russo | Stunt Coordinator |
| Sondra James | ADR Voice Casting |
| Kate Biscoe | Key Makeup Artist |
| Carl Sprague | Art Direction |
| Daniel R. Padgett | Additional Editor |
| Robert M. Andres | Key Grip |
| Dustin Smith | Grip |
| James Hamilton | Still Photographer |
| Hartsell Taylor | Wardrobe Supervisor |
| Ryan Collison | Foley Recording Engineer |
| Dominick Tavella | Sound Re-Recording Mixer |
| Judy Chin | Makeup Artist |
| Peter Waggoner | Sound Re-Recording Mixer |
| Douglas Murray | ADR Mixer |
| Michael Adkins | Wardrobe Supervisor |
| Glenfield Payne | Sound Effects Editor |
| Kenton Jakub | ADR Editor |
| Jerry DeCarlo | Key Hair Stylist |
| Frances Fiore | Unit Publicist |
| David Wahnon | First Assistant Sound Editor |
| Naomi Donne | Makeup Designer |
| Pawel Wdowczak | Sound mixer |
| Scott Peterson | Script Supervisor |
| Annette Kudrak | Music Editor |
| Branka Mrkic | Dialogue Editor |
| Susan Starr | Additional Camera |
| Andy Day | Chief Lighting Technician |
| Marie-Ange Ripka | Hair Designer |
| Chris Patterson | First Assistant Editor |
| Stephanie Biear | Seamstress |
| Sylvia Menno | Dialogue Editor |
| Kathy Kelehan | Visual Effects Producer |
| Timothy Shannon | Transportation Co-Captain |
| Robert J. Scupp | Special Effects Coordinator |
| Jennifer Lamb | Stunts |
| James P. Whalen | Transportation Captain |
| Steven Simons | Sound Re-Recording Mixer |
| Dana Ross | Color Timer |
| Christopher Donohue | Grip |
| Paul Koronkiewicz | Boom Operator |
| Lamont Crawford | Dolly Grip |
| Storn Peterson | First Assistant Camera |
| Sean Garrett Fogel | Production Coordinator |
| Kashka Banjoko | Hairstylist |
| Kathryn-Ann Oaks Shertzer | Second Second Assistant Director |
| Chris Skutch | Best Boy Grip |
| Lynda Van Damm | Production Accountant |
| Steve Speers | Second Assistant Camera |
| Eric McAllister | Assistant Sound Editor |
| Rocco Palmieri | Best Boy Electric |
| Bobby Johanson | ADR Mixer |
| Mel Cannon | Grip |
| Joanne Lamstein | Stunts |
| Penni Smith | Payroll Accountant |
| Byron Crystal | Extras Casting |
| Mark Bachman | Graphic Designer |
| Michelle L. Keiser | Second Assistant Director |
| Douglas Huszti | Assistant Art Director |
| Igor Potashanik | Grip |
| John Panuccio | Key Rigging Grip |
| Martel Thompson Hale | Makeup Artist |
| Vahram Mateosian | Tailor |
