 | Sam Worthington als Mack Phillips |
 | Octavia Spencer als Papa / Elouisa |
 | Tim McGraw als Willie |
 | Aviv Alush als Jesus |
 | Sumire Matsubara als Sarayu |
 | Radha Mitchell als Nan Phillips |
 | Graham Greene als Male Papa |
 | Gage Munroe als Jose Phillips |
 | Megan Charpentier als Kate Phillips |
 | Lane Edwards als Officer Dalton |
 | Alice Braga als Sophia |
 | Ryan Robbins als Emil Ducette |
 | Emily Holmes als Vicky Ducette |
 | Amélie Eve als Missy Phillips |
 | Jordyn Ashley Olson als Emily Ducette |
 | Laura MacKillop als Amber Ducette |
 | Derek Hamilton als Mack's Dad |
 | Tanya Hubbard als Mack's mom |
 | Carson Reaume als Young Mack Phillips |
 | David MacKay als Preacher |
 | Chris Britton als Church Deacon |
 | Kendall Cross als Special Agent Wikowski |
 | Jay Brazeau als Tony |
 | Greta Makena Gibson als Teenage Girl |
 | David Longworth als Older Camper |
 | Ty Olsson als 1950s Mack's Grandpa |
 | Leena Manro als Nurse |
 | Kayla Fielding als Aly Taylor |
 | Grace Netter als Girl on Bridge |
 | Nicholas Holmes als 1950s Young Mack's Dad |
| Brayden Snow als Meadow Kid (uncredited) |
| Kayzhia Snow als Meadow Kid (uncredited) |
| William Steinkamp | Editor |
| William Steinkamp | Co-Producer |
| Deborah Aquila | Casting |
| Declan Quinn | Director of Photography |
| Joseph C. Nemec III | Production Design |
| Aaron Zigman | Original Music Composer |
| John Fusco | Screenplay |
| Gil Netter | Producer |
| Tracey A. Doyle | Set Decoration |
| David Hadaway | Set Designer |
| Cheryl Marion | Set Designer |
| Krista Bell | Stunt Double |
| Jennifer Booth | Production Supervisor |
| Stuart Hazeldine | Director |
| Mike Drake | Executive Producer |
| Kazimir Boyle | Orchestrator |
| Patrick Kirst | Orchestrator |
| Tricia Wood | Casting |
| William Paul Young | Novel |
| Gord Hillier | Dialogue Editor |
| Gord Hillier | ADR Supervisor |
| Destin Daniel Cretton | Screenplay |
| Chris Foss | Production Manager |
| Owen Walstrom | Stunt Coordinator |
| Andy Levine | Post Production Supervisor |
| Maureen Murphy | Foley |
| Tony Lazarowich | Special Effects Coordinator |
| Monty Bannister | Location Manager |
| Jim Van Dijk | Camera Operator |
| Jim Van Dijk | Steadicam Operator |
| P.R. Tooke | Script Supervisor |
| Gary Lam | First Assistant Editor |
| Warren Mazutinec | VFX Editor |
| Myron Hoffert | First Assistant Director |
| Gwendolyn Margetson | Art Direction |
| Patti Henderson | Script Supervisor |
| Karin Nosella | Costume Design |
| Christine Coutts | Costume Supervisor |
| Stacy Caballero | Costume Design |
| Diana Adams | Production Accountant |
| Chris Higgins | Foley |
| Aaron Olson | Assistant Dialogue Editor |
| Andrew Lanham | Screenplay |
| Kimi Rosenthal | Post Production Supervisor |
| Paul Shatto | Music Editor |
| Vincent Dela Luna | Location Scout |
| Jessica Aquila Cymerman | Casting Assistant |
| Wayne Jacobsen | Novel |
| Brad Cummings | Producer |
| Brad Cummings | Novel |
| Qiuyun Long | Executive Producer |
| Lani Netter | Co-Producer |
| Sandy Lindala | Prosthetic Supervisor |
| Karin Behrenz | Third Assistant Director |
| Scott Kukurudz | Third Assistant Director |
| David Scott Thomson | Assistant Director |
| Ray Scalice | Executive Producer |
| Jake Giles Netter | Still Photographer |
| Katrina Carrasco | Post Production Assistant |
| Eric Van Dyn Hoven | Post Production Assistant |
| David Paul Wichert | Location Manager |
| James Giddy | Location Scout |
| Anastasia Brown | Music Supervisor |
