 | Humphrey Bogart als Fred C. Dobbs |
 | Walter Huston als Howard |
 | Tim Holt als Bob Curtin |
 | Bruce Bennett als James Cody |
 | Barton MacLane als Pat McCormick |
 | Alfonso Bedoya als Gold Hat |
 | Arturo Soto Rangel als El Presidente |
 | Manuel Dondé als El Jefe |
 | José Torvay als Pablo |
 | Margarito Luna als Pancho |
 | Robert Blake als Mexican Boy Selling Lottery Tickets (uncredited) |
| Guillermo Calles als Mexican Storeowner (uncredited) |
 | Roberto Cañedo als Mexican Lieutenant (uncredited) |
| Spencer Chan als Proprietor (uncredited) |
 | Jacqueline Dalya als Flashy Girl (uncredited) |
 | Ralph Dunn als Flophouse Bum (uncredited) |
| Ernesto Escoto als Mexican Bandit (uncredited) |
 | Pat Flaherty als Customer in Bar Who Warns Curtin and Dobbs about Pat McCormick (uncredited) |
 | Martín Garralaga als Railroad Conductor (uncredited) |
 | Jack Holt als Flophouse Bum (uncredited) |
 | John Huston als American in Tampico in White Suit (uncredited) |
| Francisco Islas als Indian (uncredited) |
| Mario Mancilla als Child (uncredited) |
 | Julian Rivero als Barber (uncredited) |
 | Jay Silverheels als Indian Guide at Pier (uncredited) |
 | Ray Spiker als Workman at Pier (uncredited) |
| Valdespino als Indian (uncredited) |
| Ildefonso Vega als Indian (uncredited) |
 | Harry J. Vejar als Bartender (uncredited) |
| Ignacio Villalbazo als Mexican Bandit (uncredited) |
 | Clifton Young als Flophouse Bum (uncredited) |
| Ángela Rodríguez als Howard's Assistant |
| John Huston | Director |
| B. Traven | Novel |
| John Huston | Screenplay |
| Henry Blanke | Producer |
| Jack L. Warner | Executive Producer |
| Ted D. McCord | Director of Photography |
| Owen Marks | Editor |
| Harvey Parry | Stunts |
| Leo F. Forbstein | Music Director |
| Perc Westmore | Makeup Artist |
| Fred M. MacLean | Set Decoration |
| John Prettyman | Assistant Director |
| William C. McGann | Special Effects |
| Murray Cutter | Orchestrator |
| Mac Julian | Still Photographer |
| Hans F. Koenekamp | Special Effects |
| Max Steiner | Original Music Composer |
| John Hughes | Art Direction |
| Frank McCoy | Makeup Artist |
| Monty Westmore | Makeup Artist |
| Don Alvarado | Production Manager |
| Richard Maybery | Assistant Director |
| Robert B. Lee | Sound |
| Rafael Ruiz Esparza | Sound |
| Edward Ullman | Sound Recordist |
| Eddie Craven | Special Effects |
| David Sharpe | Stunts |
| Ernesto A. Romero | Other |
| Antonio Arriaga | Other |
| Betty Delmont | Hairstylist |
