 | Glenn Close als Dr. Elaine Keener (segments "This is Dr. Keener" and "Fantasies about Rebecca") |
 | Calista Flockhart als Christine Taylor (segments "Goodnight Lilly, Goodnight Christine" and "This is Dr. Keener") |
 | Holly Hunter als Rebecca Waynon (segment "Fantasies About Rebecca") |
 | Cameron Diaz als Carol Faber (segment "Love Waits For Kathy") |
 | Kathy Baker als Rose (segments "Someone For Rose" and "Fantasies about Rebecca") |
 | Amy Brenneman als Detective Kathy Faber (segment "Love Waits For Kathy") |
 | Gregory Hines als Robert (segment "Fantasies About Rebecca") |
 | Valeria Golino als Lilly (segment "Goodnight Lilly, Goodnight Christine") |
 | Matt Craven als Walter (segments "Fantasies About Rebecca" and "Love Waits For Kathy") |
 | Miguel Sandoval als Sam (segment "Love Waits For Kathy") |
 | Roma Maffia als Debbie (segments "Fantasies About Rebecca" and "Love Waits For Kathy") |
 | Penelope Allen als Nancy (segment "Fantasies About Rebecca") |
 | Noah Fleiss als Jay (segment "Someone For Rose") |
 | Danny Woodburn als Albert (segments "Someone For Rose" and "Love Waits For Kathy") |
 | Irma St. Paule als Elaine's Mother (segment "This is Dr. Keener") |
 | Laura Leigh Hughes als Receptionist (segment "Fantasies About Rebecca") |
 | Elpidia Carrillo als Carmen Alba |
 | Mika Boorem als June (segments "Love Waits For Kathy" and "Goodnight Lilly, Goodnight Christine") |
 | Juanita Jennings |
 | Erik King |
| Emmanuel Lubezki | Director of Photography |
| Rodrigo García | Director |
| Marsha Oglesby | Producer |
| Jon Avnet | Producer |
| Ed Shearmur | Original Music Composer |
| Rodrigo García | Screenplay |
| Elie Samaha | Executive Producer |
| Lisa Lindstrom | Producer |
| Andrew Stevens | Executive Producer |
| Amy E. Duddleston | Editor |
