 | Matt Damon als Cale Tucker (voice) |
 | Bill Pullman als Captain Korso (voice) |
 | Drew Barrymore als Akima (voice) |
 | John Leguizamo als Gune (voice) |
 | Nathan Lane als Preed (voice) |
 | Janeane Garofalo als Stith (voice) |
 | Ron Perlman als Prof. Sam Tucker (voice) |
 | Alex D. Linz als Young Cale (voice) |
 | Tone Loc als Tek (voice) |
 | Jim Breuer als The Cook (voice) |
 | Jim Cummings als Chowquin (voice) |
 | Charles Rocket als Firrikash (voice) |
 | Ken Hudson Campbell als Po (voice) |
 | Tsai Chin als Old Woman (voice) |
 | Crystal Scales als Drifter Girl (voice) |
 | David L. Lander als Mayor of New Bangkok (voice) |
 | Roger L. Jackson als First alien (voice) |
 | Chris Scarabosio als Queen Drej (voice) |
 | Elaine A. Clark als Citizen (voice) |
| Leslie Hedger als First Human (voice) |
| Roy Conrad als Second Human (voice) |
| Thomas A. Chantler als Male Announcer (voice) |
| Paul Martin Smith | Editor |
| David Kirschner | Producer |
| Don Bluth | Director |
| Bob Bender | Editor |
| Fiona Trayler | Editor |
| Don Bluth | Producer |
| Tim Simonec | Original Music Composer |
| Graeme Revell | Original Music Composer |
| Gary Goldman | Producer |
| Hans Bauer | Story |
| Marion Levine | Casting |
| Kenneth Valentine Slevin | Art Direction |
| Kym Barrett | Costume Design |
| Philip A. Cruden | Production Design |
| Christopher Starnes | Visual Effects Editor |
| Paul Dutton | Animation |
| George Villaflor | Visual Development |
| Gary Goldman | Director |
| Jean Kalile | Animation |
| Steve Cunningham | Animation |
| Blair Kitchen | Animation |
| Robert Sprathoff | Animation |
| Elizabeth McClurg | Compositors |
| Darren Griffiths | Visual Effects Editor |
| Jessica Wolff | Compositors |
| Brandon Blevins | Compositors |
| Fred A. Reilly | Layout |
| David J. Hardy | Visual Development |
| Juan 'Jo' Luna | Layout |
| Troylan B. Caro | Layout |
| Manny DeGuzman | Animation |
| Gary Summers | Sound Re-Recording Mixer |
| Christopher Boyes | Sound Designer |
| Christopher Boyes | Sound Re-Recording Mixer |
| Andrea Gard | Sound Effects Editor |
| Matthew Wood | Supervising Sound Editor |
| Glen Ballard | Music Supervisor |
| John August | Screenplay |
| Joss Whedon | Screenplay |
| Joshua Winget | Music Editor |
| Randall McCormick | Story |
| Ben Edlund | Screenplay |
| Paul J. Kelly | Animation Supervisor |
| Louise Zingarelli | Character Designer |
| Wayne D. Barlowe | Character Designer |
| Raleigh L. Swick II | 3D Modeller |
| Chandra Joy Hagopian | Visual Effects Producer |
| Scott Olson | Animation |
| Dan Whiting | Animation |
| Rick Rogers | Animation |
| David Dozoretz | Visual Effects Supervisor |
| Charlie Breakiron | Special Effects Coordinator |
| Len Simon | Animation Director |
| Jan Carlee | Animation Director |
| Matthew A. Ward | 3D Animator |
| Patricia Frazier | 3D Artist |
| Russell G. Chong | Concept Artist |
