 | Nicky Whelan als Madison Taylor |
 | Bruce Willis als Lt. Det. Wakes |
 | Steve Guttenberg als Dr. Jones |
 | Tito Ortiz als Det. Pierce |
 | Texas Battle als Sergeant Tull |
 | Roman Mitichyan als CSS Roman |
 | Tyler Jon Olson als Det. Tony Martin |
 | Catherine Davis als Emily Taylor |
 | Sergio Rizzuto als Marcos |
 | Lala Kent als Renee |
 | Lydia Styslinger als Lorie |
 | Jaime Irizarry als Hospital Janitor |
 | Lynn Gilmartin als Coroner Nurse Crystal |
 | Leslee Emmett als Stern Nurse |
 | Jonathan Galanis als Officer Jacobs |
| Carroll 'Pinky' Duwart III als Security Officer Carroll |
| Koldo Fombellida als Security Supervisor |
 | Katira Maria als Dr. Jane Wallace |
| Alanna Tremblay als ER Nurse Amber |
| Samantha Rakell als ER Admitting Nurse Maria |
 | Adam Huel Potter als Homeless Man |
| Jesse Pruett als Customer Phil |
 | David B. Meadows als Flashback Dr. Mark |
 | Heather Johansen als Nurse Rachel |
| Kathryn Wrenn Woods als Clara |
 | Reila Aphrodite als Naomi (uncredited) |
| Jean Pierre Prats als Hospital Doctor (uncredited) |
| Orlando Rodriguez als Policeman (uncredited) |
| Don Abbatiello als Jimmy / Drug Dealer (uncredited) |
| Matt Eskandari | Director |
| George Furla | Producer |
| Laura Magruder | Still Photographer |
| Rafael Pérez | Special Effects Coordinator |
| Luillo Ruiz | Producer |
| Gladys Bustos | Property Master |
| Gustavo Accetta | Electrician |
| Coraly Santaliz | Script Supervisor |
| Francisco Cueto | Visual Effects Supervisor |
| Daniele Carli | Sound Effects Editor |
| R.J. Cooper | Editor |
| Tristan Baylis | ADR Mixer |
| Randall Emmett | Producer |
| Carlos 'Carly' Antunez | Set Dresser |
| Arturo Melero | Best Boy Electric |
| Carlos Zayas | Camera Operator |
| Ali Lammari | Key Costumer |
| Bryan Koss | Director of Photography |
| Carlos Cali Rivera | Electrician |
| Yagmur Kaplan | Sound Re-Recording Mixer |
| Brian Berger | Sound Effects Editor |
| Gabriel Padilla | Gaffer |
| Mark Stewart | Producer |
| Don Abbatiello | Stunt Coordinator |
| Hilda Somarriba | Public Relations |
| Douglas W. McHenry | Production Accountant |
| Victor Rosario | Casting Associate |
| Anabelle Rodriguez | Extras Casting |
| Stuart F. Wilson | Stunt Double |
| Sebastian Vázquez | Stunt Double |
| Ronal Tejada | Stunt Double |
| Penny Staffa | Utility Stunts |
| Allison Caetano | Stunt Double |
| Carlos Tirado Beltrán | Stunt Double |
| Henry Winterstern | Executive Producer |
| Stan Wertlieb | Executive Producer |
| Paul Weinberg | Executive Producer |
| Belly Torres | Co-Producer |
| Luke Taylor | Executive Producer |
| Timothy C. Sullivan | Executive Producer |
| Dustin Sloan | Associate Producer |
| Igor Shllimovich | Associate Producer |
| Ceasar Richbow | Executive Producer |
| Gary Raskin | Executive Producer |
| Bobby Ranghelov | Co-Producer |
| Diana Príncipe | Executive Producer |
| Elizabeth Primm | Associate Producer |
| Delphine Perrier | Executive Producer |
| Cyril Megret | Executive Producer |
| Walter Josten | Executive Producer |
| Lydia Hull | Executive Producer |
| Matthew Helderman | Executive Producer |
| Eric Harbert | Associate Producer |
| Tyler Gould | Executive Producer |
| Bernie Gewissler | Line Producer |
| Arianne Fraser | Executive Producer |
| Ted Fox | Executive Producer |
| Alex Eckert | Executive Producer |
| Charlie Dombek | Executive Producer |
| Alana Crow | Co-Producer |
| Grady Craig | Executive Producer |
| Alastair Burlingham | Executive Producer |
| Barry Brooker | Executive Producer |
| Montgomery Blencowe | Executive Producer |
| Ryan S. Black | Co-Executive Producer |
| Lizzie Cuello Gebetsberger | Production Design |
| Natalia Rosa | Art Direction |
| Paul J. Da Silva | Screenplay |
| Ana C. Ramirez Velez | Costume Designer |
| Mike Burns | Music Supervisor |
| Nima Fakhrara | Original Music Composer |
| Adrienne Franciscus | Unit Production Manager |
| Jonathan Southard | First Assistant Director |
| Lucía Castellano Vega | Second Assistant Director |
