 | Helen Hunt als Dr. Jo Harding |
 | Bill Paxton als Bill Harding |
 | Cary Elwes als Dr. Jonas Miller |
 | Jami Gertz als Dr. Melissa Reeves |
 | Philip Seymour Hoffman als Dustin Davis |
 | Lois Smith als Meg Greene |
 | Alan Ruck als Robert 'Rabbit' Nurick |
 | Sean Whalen als Allan Sanders |
 | Scott Thomson als Jason 'Preacher' Rowe |
 | Todd Field als Tim 'Beltzer' Lewis |
 | Joey Slotnick als Joey |
 | Wendle Josepher als Haynes |
 | Jeremy Davies als Laurence |
 | Zach Grenier als Eddie |
 | Gregory Sporleder als Willie |
 | Patrick Fischler als The Communicator |
 | Nicholas Sadler als Kubrick |
 | Ben Weber als Stanley |
 | Anthony Rapp als Tony |
 | Erik LaRay Harvey als Eric |
 | Abraham Benrubi als Bubba |
 | Jake Busey als Mobile Lab Technician |
 | Melanie Hoopes als Patty |
 | Alexa PenaVega als Jo Harding age 6 |
 | Rusty Schwimmer als Mrs. Thornton |
 | Richard Lineback als Mr. Thornton |
 | J. Dean Lindsay als Dean |
| Dan Kelpine als Diner Mechanic |
| Sharonlyn Morrow als Waitress |
| Richard Lineback als Mr. Thorton |
| Rusty Schwimmer als Mrs. Thorton |
 | Taylor Gilbert als Bryce, NSSL Scientist |
 | Bruce Wright als Murphy, NSSL Scientist |
| Gary England als TV Meteorologist #1 |
| Jeff Lazalier als TV Meteorologist #2 |
| Rick Mitchell als TV Meteorologist #3 |
| Paul Douglas als Bodger |
| Samantha McDonald als Drive-in Girl |
| Jennifer L. Hamilton als Drive-In Girl |
| Anneke de Bont als Farm Girl |
 | Darryl Cox als Four Corners Mechanic (uncredited) |
| Jack N. Green | Director of Photography |
| Hans Zimmer | Music Producer |
| Bill Coe | First Assistant Camera |
| Steven Spielberg | Executive Producer |
| Kathleen Kennedy | Producer |
| Michael Kahn | Editor |
| Jan de Bont | Director |
| Gerald R. Molen | Executive Producer |
| Walter F. Parkes | Executive Producer |
| Ronald R. Reiss | Set Decoration |
| Risa Bramon Garcia | Casting |
| Ellen Mirojnick | Costume Design |
| Michael Crichton | Screenplay |
| Michael Crichton | Producer |
| John Frazier | Special Effects Supervisor |
| Ian Bryce | Producer |
| Laurie MacDonald | Executive Producer |
| Zigmund Gron | Music Editor |
| Anne-Marie Martin | Screenplay |
| Glenn Salloum | Associate Producer |
| Mark Mancina | Original Music Composer |
| Joseph C. Nemec III | Production Design |
| Karen Blynder | Makeup Artist |
| R. Anthony Brown | Unit Production Manager |
| Bradley M. Goodman | Post Production Supervisor |
| Dan Olexiewicz | Supervising Art Director |
| Robert Deschaine | ADR Mixer |
| Tami Treadwell | ADR Recordist |
| Teresa Eckton | Sound Effects Editor |
| Alexander Witt | Second Unit Director |
| Mic Rodgers | Stunt Coordinator |
| Patrick M. Sullivan | Set Designer |
| Randi Hiller | Casting Associate |
| Richard Byard | Assistant Editor |
| Ricki Maslar | Location Casting |
| Stefen Fangmeier | Visual Effects Supervisor |
| Alan Cody | Associate Editor |
| Don Harper | Conductor |
| Budd Carr | Music Supervisor |
| Matthew Carlisle | First Assistant Director |
| Ronnie Rondell Jr. | Stunts |
| Ria Pavia | Casting Associate |
| Ken Ryan | Production Accountant |
| Stephen Hunter Flick | Supervising Sound Editor |
| Beau Baker | Boom Operator |
| Steve Maslow | Sound Re-Recording Mixer |
| Bruce Fowler | Orchestrator |
| Kyle Cooper | Title Designer |
| Guy Hendrix Dyas | Visual Effects Art Director |
| Nick Scarano | Wardrobe Supervisor |
| Steve Callas | Construction Coordinator |
| Trudy Ramirez | Script Supervisor |
| Gregg Landaker | Sound Re-Recording Mixer |
| Ron Poniewaz Jr. | Transportation Captain |
| Hilda Hodges | Foley Artist |
| William S. Maxwell III | Leadman |
| Michael J. Burmeister | Location Manager |
| Brad Wilder | Makeup Supervisor |
| John Zemansky | Property Master |
| Stephen S. Campanelli | Camera Operator |
| David Luckenbach | Steadicam Operator |
| Kevin O’Connell | Sound Re-Recording Mixer |
| Randy Peters | Transportation Coordinator |
| Jeanmarie King | Visual Effects Coordinator |
| Tommy J. Huff | Stunts |
| David James | Still Photographer |
| Stan Blackwell | Special Effects Technician |
| James M. Halty | Stunts |
| Amanda Brand | Publicist |
| Henry LaBounta | Visual Effects |
| Stephanie Flack | Dialogue Editor |
| Kim Santantonio | Hairstylist |
| Mark Mele | Rigging Gaffer |
| Kaylene Carlson | Location Coordinator |
| Carla S. Nemec | Art Department Coordinator |
| Carolyn Tapp | Foley Recordist |
| Lori Arnold | Visual Effects Production Assistant |
| William Jacobs | Sound Editor |
| David H. Neale | Electrician |
| Timothy Eaton | Visual Effects Editor |
| Linda Yeaney | First Assistant Sound Editor |
| Ken Nielsen | Visual Effects |
| Mary Jo Lang | Foley Mixer |
| Kim Bromley | Visual Effects Producer |
| Geoffrey Patterson | Sound Mixer |
| Carolyn Dessert | Costumer |
| Michael Runyard | Stunt Coordinator |
| Leah Brown | Key Costumer |
| Ralph Mendoza | Assistant Camera |
| Emmanuel Vouniozos | Rigging Grip |
| Raymond Bulinski | Craft Service |
| Joel Sill | Music Supervisor |
| Beth Bergeron | ADR Editor |
| Rory Enke | Location Scout |
| Alia Agha | Rotoscoping Artist |
| Richard Castro | Payroll Accountant |
| Bob Putynkowski | Color Timer |
| Timothy Greenwood | Projection |
| Julie Adrianson-Neary | Digital Compositors |
| Robert Mehnert | Aerial Director of Photography |
| Adam Colunga | Best Boy Grip |
| Robert L. Thompson | Construction Foreman |
| Jeffrey A. Johnson | Grip |
| Raul Essig | CG Artist |
| Mo Henry | Negative Cutter |
| Fireball Tim Lawrence | Storyboard |
| Giacomo G. Ghiazza | Production Illustrator |
| Richard Oswald | Second Assistant Director |
| Mark Suveg | Video Assist Operator |
| Catherine Calleson | Assistant Sound Editor |
| Jill McGraw | Scenic Artist |
| Keith Banks | Second Assistant Camera |
| Daniel R. Bentley | Assistant Property Master |
| Christopher J. Tuck | Stunts |
| Judee Flick | Supervising ADR Editor |
| C. Ashley Sudge | Dolly Grip |
| Chuck Parker | Assistant Art Director |
| John Aldays | Greensman |
| Dave Margolin | Painter |
| Mark Hudson | Standby Painter |
| Ron Cooney | Key Grip |
| Kenneth Sayers | Set Dressing Artist |
| Tom Osman | Carpenter |
| Mitch Friedman | Driver |
| Florian Kainz | Software Engineer |
| Steven Chambers | Stunts |
| Sheridan Ross Batson | Transportation Co-Captain |
| Annie Ellis | Stunts |
| Annie Ellis | Stunt Double |
| Robert Gray | Swing |
| Ronn Brown | Matte Painter |
| David K. Riebel | Additional Second Assistant Director |
| John M. Morse | Second Second Assistant Director |
| Stacy Layne Kramer | Assistant Accountant |
| Bonnie Bott | Assistant Location Manager |
| Terrie Nettles | Set Painter |
| Amy Dunn | Assistant Music Supervisor |
| Kevin Laffey | Music Consultant |
| Kirk Miller | Assistant Chief Lighting Technician |
| Richard Cronn | Chief Lighting Technician |
| Justin Holstein | Production Assistant |
| Melissa Bolton | Production Secretary |
| Harold Brooks | Technical Advisor |
| Danny Rogers | Stunts |
| Bill Palmer | Transportation Co-Captain |
