 | Angela Bassett als Detective Rita Veder |
 | Eddie Murphy als Maximillian / Pauly / Guido |
 | Allen Payne als Detective Justice |
 | Kadeem Hardison als Julius Jones |
 | John Witherspoon als Silas Green |
 | Zakes Mokae als Dr. Zeko |
 | Joanna Cassidy als Capt. Dewey |
 | Jerry Hall als Woman in Park |
 | Simbi Khali als Nikki |
 | Vickilyn Reynolds als Mrs. Brown |
 | Messiri Freeman als Eva, Julius' Girl |
| Kelly Cinnante als Policewoman Photographer |
 | Jsu Garcia als Anthony |
 | W. Earl Brown als Thrasher |
| Ayo Adeyemi als Bartender |
| Troy Curvey Jr. als Choir Leader |
| William Blount als Deacon Brown |
| Joe Costanza als Bear |
 | John LaMotta als Lizzy |
 | Marcelo Tubert als Waiter at Caprisi's |
| Nick DeMauro als Kitty Caprisi |
| Mark Haining als Man in Park |
 | Wendy Robie als Zealot at Police Station |
| Alyse Mandel als Policewoman |
| Larry Paul Marshall als Greeter at Church |
| Vince Micelli als Checkers Player |
| Oren Waters als Singer |
| Carlton Davis als Singer |
| Clive Ross als Singer |
| Michael Hyde als Singer |
| Maxine Waters Willard als Singer |
| Josef Powell als Singer |
| Roy Galloway als Singer |
| Carmen Carter als Singer |
| Julia Waters als Singer |
 | Carmen Twillie als Singer |
 | Ray Combs als Game Show Host |
 | Mitch Pileggi als Tony the Hitman |
| Ken Tipton als Thug |
| Wes Craven | Director |
| Stuart M. Besser | Executive Producer |
| Mark Lipsky | Producer |
| Marianne Maddalena | Executive Producer |
| Eddie Murphy | Producer |
| Charlie Murphy | Screenplay |
| Michael Lucker | Screenplay |
| Chris Parker | Screenplay |
| J. Peter Robinson | Music |
| Mark Irwin | Director of Photography |
| Patrick Lussier | Editor |
| Thomas Rosales Jr. | Stunts |
| Ronnie Rondell Jr. | Stunts |
| Charlie Picerni | Stunts |
| Dane Farwell | Stunts |
| Sonja Davis | Stunts |
| Alan Oliney | Stunt Coordinator |
| Charlie Murphy | Story |
| Eddie Murphy | Story |
| Ray Murphy Sr. | Co-Producer |
| Dixie J. Capp | Co-Producer |
| Eileen Mack Knight | Casting |
| Gary Diamond | Art Direction |
| Cynthia Kay Charette | Art Direction |
| Ha Nguyen | Costume Designer |
| Bob Kensinger | Set Decoration |
| Bernadine M. Anderson | Makeup Supervisor |
| Marie Carter | Makeup Artist |
| William Howard | Hair Supervisor |
| Erma Kent | Hairstylist |
| Toy Van Lierop | Makeup Artist |
| Nicholas Mastandrea | First Assistant Director |
| Peter Chesney | Second Unit Director |
| Henry Alberti | Set Designer |
| Hayley H. Hsu | Second Assistant Director |
| Phil Dagort | Set Designer |
| Roberta Doheny | Sound Re-Recording Mixer |
| Paul B. Clay | Sound Designer |
| Peter Reale | Sound Re-Recording Mixer |
| Tim Philben | Sound Re-Recording Mixer |
| Peter Chesney | Special Effects |
| Alex Brown | Stunts |
| LaFaye Baker | Stunts |
| Mark Hicks | Stunts |
| Gary Littlejohn | Stunts |
| Kym Washington Longino | Stunts |
| Irving E. Lewis | Stunts |
| Rusty McClennon | Stunts |
| Dennis Madalone | Stunts |
| Buck McDancer | Stunts |
| Wayne Montanio | Stunts |
| Bob McGovern | Stunts |
| Gary Price | Stunts |
| Sharon Schaffer | Stunts |
| Tony Cutrono | Second Unit Director of Photography |
| Jay W. Yowler | Gaffer |
| Robert D. Tomer | Second Unit Director of Photography |
| Eartha Robinson | Choreographer |
| Douy Swofford | Title Designer |
