 | James McAvoy als Wesley Gibson |
 | Angelina Jolie als Fox |
 | Morgan Freeman als Sloan |
 | Terence Stamp als Pekwarsky |
 | Thomas Kretschmann als Cross |
 | Common als The Gunsmith |
 | Kristen Hager als Cathy |
 | Marc Warren als The Repairman |
 | David O'Hara als Mr. X |
 | Dato Bakhtadze als The Butcher |
 | Konstantin Khabenskiy als The Exterminator |
 | Chris Pratt als Barry |
 | Lorna Scott als Janice |
 | Sophiya Haque als Puya |
 | Brian Caspe als The Pharmacist |
| Mark O'Neal als Co-Worker |
| Bridget McManus als Check-Out Girl |
 | Brad Calcaterra als Assassin (uncredited) |
 | Mike Whyte als Businessman (uncredited) |
 | Claudia DiBiccari als Pedestrian (uncredited) |
| Julia Copeland als Driver (uncredited) |
| Mitchell Amundsen | Director of Photography |
| Jim Lemley | Producer |
| Jason Netter | Producer |
| Iain Smith | Producer |
| Derek Haas | Screenplay |
| Michael Brandt | Screenplay |
| Chris Morgan | Screenplay |
| David Brenner | Editor |
| John Myhre | Production Design |
| Roger Birnbaum | Executive Producer |
| Gary Barber | Executive Producer |
| Jeff Kirschenbaum | Executive Producer |
| Geyer Kosinski | Executive Producer |
| Adam Siegel | Executive Producer |
| Marc Silvestri | Executive Producer |
| Danny Elfman | Original Music Composer |
| Timur Bekmambetov | Director |
| Mindy Marin | Casting |
| David Baxa | Art Direction |
| Patrick M. Sullivan | Art Direction |
| Martin Vačkář | Art Direction |
| Richard Roberts | Set Decoration |
| Varvara Avdyushko | Costume Design |
| Giovanni Casalnuovo | Costume Supervisor |
| Stanislava Šlosserová | Costume Supervisor |
| Marc Platt | Producer |
| Tomas Voth | Supervising Art Director |
| Wylie Stateman | Supervising Sound Editor |
| Chris Jenkins | Sound Re-Recording Mixer |
| Frank A. Montaño | Sound Re-Recording Mixer |
| Petr Forejt | Production Sound Mixer |
| Rudra Banerji | Set Production Assistant |
| Chris Cleek | Assistant Art Director |
| Rick James | Camera Trainee |
| Sally French | Unit Production Manager |
| Sally French | Co-Producer |
| Luc Etienne | First Assistant Director |
| Mic Rodgers | Stunt Coordinator |
| Nick Gillard | Stunt Coordinator |
| Martin Hub | Stunt Coordinator |
| Rick LeFevour | Stunt Coordinator |
| C.C. Smiff | Fight Choreographer |
| Jared LeBoff | Co-Producer |
| Stefen Fangmeier | Visual Effects Supervisor |
| Jon Farhat | Visual Effects Supervisor |
| Juliette Yager | Visual Effects Producer |
| Bara Bucherova | Assistant Set Decoration |
| Katerina Koutská | Set Designer |
| David Vondrasek | Set Designer |
| Frantisek Weber | Set Designer |
| Steven M. Saylor | Set Designer |
| Allan M. Fleischmann | Set Designer |
| Dallas Puett | Additional Editing |
| Samuel Craven | Additional Editing |
| Gregory B. Peña | Costume Supervisor |
| Frances Hannon | Makeup Designer |
| Julie Dartnell | Makeup Artist |
| Carmel Jackson | Makeup Artist |
| Gemma Richards | Makeup Artist |
| Adéla Robová | Makeup Artist |
| Nancy Hancock | Makeup Artist |
| Linda de Vetta | Makeup Artist |
| Lori Wyant | Script Supervisor |
| Dmitry Kiselev | Second Unit Director |
| Mark Millar | Comic Book |
| J.G. Jones | Comic Book |
| John Toll | Additional Photography |
| Debbie Evans | Stunt Driver |
| Jophery C. Brown | Stunts |
| Henry Kingi | Stunts |
| Freddie Hice | Stunts |
| Laura Albert | Stunts |
| Mic Rodgers | Second Unit Director |
| René Stejskal | Makeup Designer |
| Frances Hannon | Hair Designer |
| Carmel Jackson | Hairstylist |
| Julie Dartnell | Hairstylist |
| Adéla Robová | Hairstylist |
| Gemma Richards | Hairstylist |
| John D. Milinac | Special Effects Coordinator |
| Dominic Tuohy | Special Effects |
| Dean Bailey | Stunts |
| Chris Barnes | Stunt Double |
| Kenny Alexander | Stunts |
| Veronika Bellová | Stunt Double |
| Chris Cenatiempo | Stunt Driver |
| Gary Baxley | Stunts |
| Gilbert B. Combs | Stunts |
| Roy Farfel | Stunt Driver |
| Frank Ferrara | Stunt Driver |
| James M. Halty | Stunts |
| Thomas Robinson Harper | Stunts |
| Cort Hessler | Stunt Driver |
| Jennifer Lamb | Stunts |
| Ross A. Jordan | Stunt Driver |
| Maurice Lee | Stunt Double |
| Billy D. Lucas | Stunts |
| John C. Meier | Stunts |
| Carl Paoli | Stunt Driver |
| Jason Rodriguez | Utility Stunts |
| Michael Runyard | Stunts |
| Linda Perlin | Stunt Driver |
| Jaroslav Peterka | Stunts |
| Eunice Huthart | Stunt Double |
| Jindřich Klaus | Stunts |
| Riley Harper | Stunt Double |
| Mark Henson | Stunts |
| Alicia Skirball | Stunt Double |
| Jeff Shannon | Stunt Double |
| Roman Spacil | Stunts |
| Kevin Sorensen | Stunts |
| Leo Stransky | Stunt Double |
| Richard C. Taylor | Utility Stunts |
| Keith Tellez | Stunts |
| Tim Trella | Stunts |
| Leonard Woodcock | Stunts |
| Todd Rogers Terry | Stunts |
| Scott Workman | Stunt Driver |
| Keith Woulard | Stunts |
| Greg Tracy | Stunts |
| Rudolf Vrba | Stunt Double |
| Ivo Zubaty | Stunts |
| Danny Wynands | Stunts |
| Samantha MacIvor | Stunts |
| Craig Lyn | Visual Effects Supervisor |
| George Richmond | Camera Operator |
| George Richmond | Steadicam Operator |
