 | Mel Gibson als Nick Marshall |
 | Helen Hunt als Darcy McGuire |
 | Marisa Tomei als Lola |
 | Alan Alda als Dan Wanamaker |
 | Ashley Johnson als Alex Marshall |
 | Mark Feuerstein als Morgan Farwell |
 | Lauren Holly als Gigi |
 | Delta Burke als Eve |
 | Valerie Perrine als Margo |
 | Judy Greer als Erin |
 | Sarah Paulson als Annie |
 | Ana Gasteyer als Sue Cranston |
 | Lisa Edelstein als Dina |
 | Loretta Devine als Flo |
 | Diana Maria Riva als Stella |
 | Eric Balfour als Cameron |
 | Andrea Baker als Office Intern |
 | Robin Pearson Rose als Kitchen Secretary |
 | Christopher Emerson als Mail Room Kid |
 | Ashlee Turner als Woman in Library |
 | Sierra Pecheur als Woman at Lunch Counter |
| Joe Petcka als Man on Street |
| Brian Callaway als Man on Street |
 | Coburn Goss als Man on Street |
| Christian Michel als Man on Street |
| Perry Cavitt als Ogling Man |
| Crystal McKinney als Unimpressed Woman |
| Jeanne Marie Rice als Unimpressed Woman |
 | Kathrin Middleton als Gigi's Friend |
 | Logan Lerman als Young Nick Marshall |
| Kelly Cooper als Showgirl |
 | Palmer Davis als Showgirl |
| Katie Miller als Showgirl |
| Dana Waters als Nick's Mom |
| Gregory Cupoli als Male Role Model |
 | Alexondra Lee als Woman in Pink Sweater |
| Aviva Gale als Counter Girl |
 | Shirley Prestia als Coffee Shop Customer |
 | T.J. Thyne als Coffee Shop Customer |
| Norman H. Smith als Norm |
 | Audrey Wasilewski als Secretary with Danish / Kitchen Secretary |
 | Angela Oh als Jess, Dan's Secretary |
 | Robert Briscoe Evans als Ted |
| Chris Rolfes als Woman in Park |
 | Katie Kneeland als Woman in Park |
| Jeanine O'Connell als Woman in Park |
 | Kelley Hazen als Woman in Park |
 | Brooke Elliott als Woman in Park |
| Kristina Martin als Woman in Park |
| Harmony Rousseau als Sloane / Curtis Receptionist |
 | Lisa Long als Sloane / Curtis Executive |
| Heidi Helmer als Marshall Field's Shopper |
| Marla Martensen als Marshall Field's Shopper |
| Sally Meyers Kovler als Marshall Field's Shopper |
| Ashley Quirico als Marshall Field's Shopper |
| Regan Rohde als Marshall Field's Shopper |
| Liz Tannebaum als Marshall Field's Shopper |
 | LeShay N. Tomlinson als Marshall Field's Shopper |
 | Cristine Rose als Sloane / Curtis Attorney |
 | Arden Myrin als Darcy's Assistant |
| Rachel Duncan als Alex's Friend |
 | Alex McKenna als Alex's Friend |
| Regiane Gorski als Yoga Instructor |
| Juliandra Gillen als Woman in Library |
| Lisa Anne Hillman als Woman in Library |
| Tracy Pacheco als Woman in Library |
| Jamie Gutterman als Jogger by Lake |
 | Maggie Egan als Kitchen Secretary |
 | Juanita Jennings als Kitchen Secretary |
 | Hallie Meyers-Shyer als Girl at Lunch Counter |
| Kate Asner als Woman at Lunch Counter |
 | Caryn Greenhut als Woman at Lunch Counter |
| Jennifer Greenhut als Woman at Lunch Counter |
 | Marnie Mosiman als Woman at Lunch Counter |
| Nnenna Freelon als Nightclub Singer |
| Gil Hacohen als Haim |
| Nancy Monsarat als Nike Executive |
| Jacqueline Thomas als Nike Executive |
 | Rory Byrne als Nike Executive |
 | Victoria Garcia-Kelleher als Secretary |
| Gertrude Wong als Old Woman in Chinatown |
| Andi Eystad als Girl at Prom |
 | Greg Bronson als Upscale Pedestrian (uncredited) |
| Kira Coplin als Alex's Friend (uncredited) |
 | Kiva Dawson als Showgirl (uncredited) |
 | David C. Fisher als Restaurant Patron (uncredited) |
| Elizabeth Friedman als Classmate (uncredited) |
 | Melanie Good als Showgirl (uncredited) |
| Drew Howerton als Boy at Prom (uncredited) |
| Kimberly Lyon als Showgirl (uncredited) |
| Krista McRoberts als Angela (uncredited) |
 | Bette Midler als Dr. J. M. Perkins (uncredited) |
| Andy Schofield als Man in Park (uncredited) |
| Nancy Sinclair als Woman Getting Manicure (uncredited) |
| Melinda Songer als Dancer (uncredited) |
| Lauren Stewart als Gigi's Friend #3 (uncredited) |
| Tracey Stone als Black-Haired Beauty (uncredited) |
| Dean Teaster als Taxi Driver (uncredited) |
 | Gena Vazquez als Marshall Field's Shopper (uncredited) |
 | Nancy Wetzel als Co-worker (uncredited) |
| Alan Silvestri | Original Music Composer |
| Alan Silvestri | Conductor |
| Dean Cundey | Director of Photography |
| Howard Feuer | Casting |
| Jon Hutman | Production Design |
| Bruce Davey | Producer |
| Deborah Aquila | Casting |
| Ellen Mirojnick | Costume Design |
| Andrew Menzies | Assistant Art Director |
| Tony Fanning | Art Direction |
| Carol Littleton | Additional Editing |
| Stephen McEveety | Executive Producer |
| Karen Blynder | Makeup Artist |
| Jim Passon | Color Timer |
| Rosemary Brandenburg | Set Decoration |
| Nancy Meyers | Director |
| Nancy Meyers | Producer |
| Bruce A. Block | Co-Producer |
| Bruce A. Block | Storyboard Artist |
| Bruce A. Block | Second Unit Director |
| Thomas J. Nordberg | Editor |
| Chris Boardman | Orchestrator |
| Suzanne McCabe | Assistant Costume Designer |
| Gae S. Buckley | Art Direction |
| Susan Cartsonis | Producer |
| Matt Williams | Producer |
| Carmen Finestra | Executive Producer |
| David McFadzean | Executive Producer |
| Stephen A. Rotter | Editor |
| Julie M. Anderson | Production Coordinator |
| Michael Dennison | Costume Supervisor |
| Joe Bucaro III | Stunts |
| David Giammarco | Sound Effects Editor |
| Melissa Goddard | Production Executive |
| Matthew Cassel | Assistant Location Manager |
| Gina Matthews | Producer |
| Kelly O'Brien | Casting Assistant |
| Jason Sweers | Graphic Designer |
| Josh Goldsmith | Screenplay |
| Josh Goldsmith | Story |
| Cathy Yuspa | Screenplay |
| Cathy Yuspa | Story |
| Peter Davidian | Assistant Chief Lighting Technician |
| Bonnie Greenberg | Music Supervisor |
| Ashley Burnham | Art Department Coordinator |
| David Elliott | Construction Coordinator |
| Diane Drake | Story |
| Karyn McCarthy | Unit Production Manager |
| Tim T. Cunningham | Visual Effects Coordinator |
| Randy Singer | Foley Mixer |
| John P. Goldsmith | Set Designer |
| Wendy Washbrook | Casting Associate |
| Jason Corgan Brown | Researcher |
| Matt Byrne | Stunts |
| Lance Gilbert | Stunt Coordinator |
| Lance Gilbert | Stunt Double |
| Brad Wilder | Makeup Department Head |
| Kevin Bartnof | Foley Artist |
| Andrew Cooper | Still Photographer |
| Bill W. Benton | Additional Sound Re-Recording Mixer |
| Conny Fauser | Digital Compositors |
| Rachel Aberly | Unit Publicist |
| Candy L. Walken | Key Hair Stylist |
| Yann Denoual | Sculptor |
| Greg Steele | ADR Mixer |
| Kosta Saric | Visual Effects Editor |
| C. Marie Davis | Executive Visual Effects Producer |
| Mychael Bates | Property Master |
| Renée Tondelli | Supervising ADR Editor |
| Bryan Pennington | Dolby Consultant |
| Jeri Baker | Hairstylist |
| Sherilyn Stetz | Assistant Makeup Artist |
| Beth Miller | Hair Department Head |
| Aaron Dem | Head of Production |
| Fran Allgood | Costumer |
| Robert Ulland | Steadicam Operator |
| Robb Earnest | Assistant Production Coordinator |
| Andrew Silver | Music Consultant |
| Dennis Drummond | Supervising Sound Editor |
| Linda Folk | ADR Editor |
| Sean Landeros | Sound Recordist |
| Kim Drummond | Dialogue Editor |
| Phillip Ellman | Greensman |
| Carrie Goodman | Location Assistant |
| Craig Comstock | Additional Second Assistant Director |
| Ken Jones | Visual Effects Supervisor |
| Paula Case | Assistant Director |
| David MacMillan | Production Sound Mixer |
| David McKlveen | Carpenter |
| James Alden | Rigging Grip |
| Andrew Neujahr | Art Department Assistant |
| Alex Apple | Location Scout |
| Barry Jones | Painter |
| Darryl Henley | Production Illustrator |
| William Coss | First Assistant Camera |
| Ann Culotta | Set Costumer |
| Stacy Doran | Set Dressing Artist |
| Keith Young | Choreographer |
| Nelson Sepulveda | Digital Effects Supervisor |
| John Lybrand | Driver |
| Mike Gentile | Loader |
| J. Papajoanou | Post Production Assistant |
| Allan Johnson | Propmaker |
| Tim Werle | Set Medic |
| Jenny Fumarolo | Set Production Assistant |
| Girard Swan | Stand In |
| Armand Paoletti | Transportation Coordinator |
| Josh Levy | Video Assist Operator |
| Jim Bradfield | Electrician |
| Brady Breen | Location Manager |
| Nancy Sandberg | Production Supervisor |
| Harrison D. Marsh | Boom Operator |
| Kira Edmunds | Assistant Sound Editor |
| Jessica Trento | Visual Effects Producer |
| Jessica Mcclintock | Thanks |
| Darin Rivetti | Second Assistant Director |
| Garson Yu | Title Designer |
| Alexx Thompson | Set Painter |
| Robert A. Preston | Dolly Grip |
| Bradley T. Matthys | First Company Grip |
| Dana L. Marker | Negative Cutter |
| David Bifano | Music Programmer |
| Michael Orefice | Chief Lighting Technician |
| Michelle Stevens | Second Assistant Accountant |
| Angela Athayde | Production Assistant |
| Rick Roesch | Payroll Accountant |
| Chuck Askerneese | Assistant Property Master |
| Diane Lucas | ADR Recordist |
| Robin Zacha | Apprentice Sound Editor |
| William H. Harlow IV | Camera Loader |
| R. Scott Goodrich | Second Assistant Camera |
| Walter 'T.J.' Johnson | Second Company Grip |
| Philip Beech | Assistant Editor |
| Christy Gerhart | Music Coordinator |
| Steve Spiker | Extras Casting |
| Adrienne Swan | First Assistant Accountant |
