 | Nicolas Cage als John McLoughlin |
 | Maria Bello als Donna McLoughlin |
 | Maggie Gyllenhaal als Allison Jimeno |
 | Danny Nucci als Officer Giraldi |
 | Stephen Dorff als Scott Strauss |
 | Michael Peña als Will Jimeno |
 | Jay Hernandez als Dominick Pezzulo |
 | Michael Shannon als Dave Karnes |
 | Dorothy Lyman als Allison's Mother |
 | Peter McRobbie als Allison's Father |
 | Wass Stevens als Pat McLoughlin |
 | Frank Whaley als Chuck Sereika |
 | Stoney Westmoreland als Paddy McGee |
 | Viola Davis als Mother in Hospital with Donna |
| Lola Cook als Olivia Jimeno |
 | Connor Paolo als Steven McLoughlin |
| Anthony Piccininni als JJ McLoughlin |
| Alexa Gerasimovich als Erin McLoughlin |
| Morgan Flynn als Caitlin McLoughlin |
 | Armando Riesco als Antonio Rodrigues |
 | Jon Bernthal als Christopher Amoroso |
 | Jude Ciccolella als Inspector Fields |
 | Julie Adams als Allison's Grandmother |
| Joe Starr als Subway Rider |
| William Jimeno als Port Authority Officer |
 | Nick Damici als Lieutenant Kassimatis |
 | Martin Pfefferkorn als Homeless Addict #1 |
| Razame de la Crackers als Homeless Addict #2 |
| Nelson Peña als Street Hood #1 |
 | Marcos Palma als Street Hood #2 |
| Andre Ward als Port Authority Hustler |
| Lisa Yuen als Port Authority Tourist |
 | Cliff Bemis als Desk Cop |
| Harmonica Sunbeam als 9th Avenue Hooker |
 | Ned Eisenberg als Officer Polnicki |
 | Nicholas Turturro als Officer Colovito |
| Tyree Michael Simpson als Officer Washington |
| Kevin Feely als Plain Clothes Officer |
| Mark Elliot Wilson als Street Businessman |
 | Tawny Cypress als Bleeding Woman |
 | Robert Blanche als WTC Desk Officer |
 | Tom Wright als Officer Reynolds |
| Terry Quinn als Fire Fighter in Concourse |
| Ed Jewett als Wisconsin Cop |
| Maria Helan als Allison's Co-Worker |
 | Brad William Henke als Allison's Brother |
 | Patti D'Arbanville als Donna's Neighbor |
 | Donna Murphy als Judy Jonas |
 | Nicky Katt als Volunteer Fireman |
 | Lucia Brawley als Will's Sister |
 | Kimberly Scott als Sergeant King |
 | Dara Coleman als Officer Boel |
| Tiffany Romano als Bianca Jimeno |
 | Gregory Jbara als Accountant in Karnes Office |
 | Jordan Lage als Karnes' Pastor |
 | Tony Genaro als Will's Father |
| Aixa Maldonado als Will's Mother |
 | Jay Acovone als Donna's Male Neighbor |
| Howard Samuelsohn als Downtown Resident |
| David H. Ahl als National Guard Officer at Barricade |
 | Arthur J. Nascarella als Fire Chief at Ground Zero |
| Thom Prin Jr. als Fireman at Ground Zero |
| Steve Chappell als Figure of Jesus |
 | William Mapother als Marine Sergeant Thomas |
 | Thomas F. Duffy als NYC Command Centre Operator |
| Tommy Asher als Fireman in Hole |
 | Charles A. Gargano als Port Authority Commander |
| Thomas McHale als Port Authority Sergeant |
 | Lalanya Masters als Allison's Nurse |
 | Greg Collins als Will's Rescue Fireman |
| Scott Fox als Firefighter #1 John's Rescue |
| Louis Raimondi als Firefighter #2 John's Rescue |
| Victor Spadaro als Firefighter #3 John's Rescue |
| John Kiernan als Firefighter #4 John's Rescue |
| Liz A. Randall als Will's Arrival Nurse |
 | Roger Cross als Will's Doctor |
 | Jossara Jinaro als Will's Operation Nurse |
| Joseph Esposito als Fireman Joe |
 | Gary Stretch als John's Paramedic |
 | Kurt Caceres als John's Rescue Fireman |
 | John C. McGinley als Fireman (uncredited) |
| Suzanne Crowley | Casting |
| Harry Cohen | Sound Designer |
| Oliver Stone | Director |
| Todd Bryant | Stunts |
| Debra Hill | Producer |
| Mary Vernieu | Casting |
| Billy Hopkins | Casting |
| Seamus McGarvey | Director of Photography |
| Reese Spensley | Set Costumer |
| Kerry Barden | Casting |
| Michael Shamberg | Producer |
| Stacey Sher | Producer |
| David Brenner | Editor |
| Craig Armstrong | Original Music Composer |
| Craig Armstrong | Orchestrator |
| Richard L. Johnson | Art Direction |
| Gary D'Amico | Special Effects Coordinator |
| Chantal Feghali | Post Production Supervisor |
| Chantal Feghali | Visual Effects Producer |
| Chantal Feghali | Co-Producer |
| Beth A. Rubino | Set Decoration |
| Ilona Herman | Hairstylist |
| Scott Rathner | First Assistant "A" Camera |
| Norman Golightly | Executive Producer |
| Paul Schnee | Casting |
| Jan Roelfs | Production Design |
| Moritz Borman | Producer |
| Mary L. Mastro | Hair Department Head |
| Michael Dennison | Costume Design |
| Julie Monroe | Editor |
| Hinju Kim | Art Direction |
| Rick Avery | Stunts |
| Budd Carr | Music Supervisor |
| Al Cerullo | Pilot |
| Jan Foster | Unit Production Manager |
| Ron Petagna | Construction Coordinator |
| Ron Petagna | Carpenter |
| Ron Petagna | Head Carpenter |
| Jeffrey Rollins | On Set Dresser |
| Kyle Rudolph | Second Unit Director of Photography |
| Jeremy Fitzgerald | Stunt Double |
| Michael Eaves | Digital Intermediate Colorist |
| Doug Coleman | Stunt Coordinator |
| Michael Keller | Sound Re-Recording Mixer |
| John Cenatiempo | Stunts |
| Donald J. Lee Jr. | Executive Producer |
| Nerses Gezalyan | Sound Mixer |
| Jeffrey Wilhoit | Foley |
| Greg Zimmerman | ADR Recordist |
| Christopher Duskin | Camera Operator |
| Roy T. Anderson | Stunt Driver |
| Andrea Berloff | Writer |
| J.C. Cantu | Casting Associate |
| Lindsay Graham Ahanonu | Casting Assistant |
| Robert S. Wilson | Associate Producer |
| Gregory S. Hooper | Set Designer |
| François Duhamel | Still Photographer |
| Michael Pinkey | Camera Operator |
| Stephanie Finochio | Stunts |
| Robin Harlan | Foley Artist |
| Randy Singer | Foley Mixer |
| Chris Hampton | Special Effects Supervisor |
| Mindy Hall | Makeup Designer |
| Jonny Pray | Costume Supervisor |
| David M. Roberts | Boom Operator |
| David Page | Key Set Costumer |
| Scott Millan | Sound Re-Recording Mixer |
| D.R. Farquharson | Digital Intermediate Producer |
| Michael Hertlein | Dialogue Editor |
| Wylie Stateman | Supervising Sound Editor |
| Trisha Burton | Script Supervisor |
| Sarah Monat | Foley |
| Randall D. Wilkins | Set Designer |
| Stephen S. Campanelli | Additional Camera |
| Ann Scibelli | Sound Designer |
| Joe E. Rand | Music Editor |
| Jeff Brink | Special Effects Coordinator |
| Edwina Hayes | Visual Effects Producer |
| Samuel Craven | First Assistant Editor |
| Samuel Craven | Visual Effects Editor |
| Howard Samuelsohn | Dialect Coach |
| Bill Almeida | Rigging Gaffer |
| John Scheele | Visual Effects Supervisor |
| Linda Lew | Foley Editor |
| Rachel Aberly | Publicist |
| Barbara McDermott | Music Editor |
| Matthew Spiegel | Production Supervisor |
| Peter Rosenfeld | Steadicam Operator |
| Peter Rosenfeld | "A" Camera Operator |
| Ryan Cook | CG Supervisor |
| David Norris | Aerial Director of Photography |
| Diane L. Sabatini | Production Executive |
| Mike Villarino | Construction Coordinator |
| Craig Fehrman | Transportation Coordinator |
| Andy Brown | Visual Effects Supervisor |
| John G. Velez | Gaffer |
| Greg Steele | ADR Mixer |
| Laura Harris Atkinson | Dialogue Editor |
| Michael Bruce Ellis | Visual Effects Supervisor |
| Hector C. Gika | Sound Effects Editor |
| Drew Webster | Sound Mix Technician |
| Suzy Mazzarese-Allison | Key Hair Stylist |
| Peter Bebb | CG Supervisor |
| Andy Taylor | Visual Effects Producer |
| Kristopher Wright | Visual Effects Coordinator |
| Alexander Vegh | Pre-Visualization Supervisor |
| Charles Kern | Standby Painter |
| Scott Wolf | Sound Effects Editor |
| Sebastián Almeida | Assistant Camera |
| Renée Tondelli | Supervising ADR Editor |
| Renée Tondelli | Supervising Dialogue Editor |
| James Sarzotti | Makeup Artist |
| Erik Knight | Art Department Coordinator |
| Richard Diver | Visual Effects Editor |
| Anthony Simonaitis | Pyrotechnician |
| Angela Stauffer | Art Department Coordinator |
| Brett Margules | 3D Artist |
| Kenny Becker | Color Timer |
| Robert Clark | Sculptor |
| Michael Bomagat | Animation |
| Richard McBride | Visual Effects Supervisor |
| Robert Consing | Storyboard Artist |
| Eliza Coleman | Stunts |
| Daniel Boxer | Property Master |
| Kathleen Rosen | Set Decoration Buyer |
| Michael Sharpe | Assistant Costume Designer |
| Natalie Arango | Set Costumer |
| Lucia Lettini | Set Costumer |
| Kimberly Felix | Key Makeup Artist |
| Frank Didio | Construction Coordinator |
| John Pritchett | Production Sound Mixer |
| Harry Zimmerman | First Assistant "B" Camera |
| Pete Anthony | Conductor |
| Len Murach | Location Manager |
| Kevin Patrick Burns | Additional Sound Re-Recording Mixer |
| Brian Avery | Utility Stunts |
| Jim Duggan | Dolly Grip |
| Jennifer Lamb | Stunts |
| Suzanne Evans-Booth | Visual Effects Coordinator |
| Luis Moreno | Best Boy Electric |
| Matt Magnolia | Visual Effects Coordinator |
| Lindsay Adams | Digital Compositor |
| Brian Feola | Construction Foreman |
| Bruce Callahan | Driver |
| Daniel R. Kerr | Sound Editor |
| Jeff Brinker | Rigging Grip |
| Danielle Blumstein | Assistant Production Coordinator |
| Greg Gladstone | Lighting Supervisor |
| Jeffrey D. McDonald | Assistant Art Director |
| Graham Ratliff | Art Department Assistant |
| Dhamarata Dhiensuwana | Key Rigging Grip |
| David Zbriger | Visual Effects Editor |
| Ron Alexus | Electrician |
| Art Bartels | Key Grip |
| Ronnie Morgan | Assistant Sound Editor |
| Marcy Craig | Costumer |
| Simon Warnock | First Assistant Director |
| Darin Rivetti | First Assistant Director |
| Kevin Connolly | Musician |
| George Patsos | Key Grip |
| Marc Boyle | Hairstylist |
| Larissa Supplitt | Second Assistant "B" Camera |
| Stephen Caldwell | Scenic Artist |
| Irvin Gourgue | Extras Casting Assistant |
| Vaughn Arnup | Roto Supervisor |
| Gary Hildebrand | Generator Operator |
| Jack Glenn | Dolly Grip |
| Robert S. Costanzo | Co-Producer |
| Marco Nero | Matte Painter |
| Bruce Chimerofsky | Best Boy Grip |
| Danielle Giovanniello | Assistant Property Master |
| Bruce C. Knight II | Assistant Property Master |
| Jonathan Tessler | Property Master |
| Noah Bishop | Techno Crane Operator |
| Alejandro J. Castillo | Lighting Technician |
| Bhakar James | 3D Artist |
| Andrew Lodge | 3D Artist |
| Tristan North | 3D Artist |
| Tim Quarry | 3D Artist |
| Sandy Sutherland | 3D Artist |
| Phil Wittmer | 3D Artist |
| Bradley Wong | 3D Artist |
| Robert Gardiner | 3D Modeller |
| Jamee Houk | Animation Supervisor |
| Tom O'Flaherty | Animation |
| Dori Arazi | Animation |
| Nowell Valeri | Matchmove Supervisor |
| Georgia Scheele | Visual Effects Coordinator |
| Carol Corwin | Visual Effects Producer |
| August Meredith | Visual Effects Technical Director |
| Toshiyasu Otsuka | Visual Effects Technical Director |
| Enrique Vila | Visual Effects Technical Director |
| Bob Fernley | Digital Intermediate |
| Jeremy Pitts | Foley Editor |
| Kathryn-Ann Oaks Shertzer | First Assistant Director |
| Joe White | Utility Sound |
| Meegan E. Godfrey | Utility Stunts |
| Nicole Zaks | Set Decorating Coordinator |
| Lance Mayer | Libra Head Technician |
| Garnet Baril | Special Effects Technician |
| Eric Amundsen | Second Assistant "A" Camera |
| Jason Porter | Compositing Supervisor |
| Paul Farley | Grip |
| Sasha Adkinson | Extras Casting |
| George Hess | Swing |
| Michael Riolo | Art Department Production Assistant |
| Laura LeFaivre | Visual Effects Production Manager |
| Chris Bennett | Lighting Programmer |
| Joshua Loiko | Second Assistant Accountant |
| Maggie Murphy | Second Assistant Director |
| Bradley Morris | Second Second Assistant Director |
| Vincent Guarriello | Key Construction Grip |
| Heather P. Woods | Post Production Coordinator |
| Kim Lincoln | Graphic Designer |
| Rafael Lima | Location Assistant |
| James P. Cullen | Key Costumer |
| Jason Dock Harrell | Propmaker |
| Mark D. Houston | Assistant Accountant |
| Peter I. Sabat | Production Coordinator |
| Clovis Chamberet | Leadman |
| Richard Ewan | Painter |
| Chad B. Daring | Set Dresser |
| Steven Shellooe | Ager/Dyer |
| David Sooc | Editorial Production Assistant |
| Lauren Fritz | Location Scout |
| David Urich | Transportation Captain |
| Paul Baker | Props |
| Michael A. Becker | Craft Service |
| Cate Eckenrode | Set Production Assistant |
| Mic Tomasi | Stand In |
| Cameron Duncan | Camera Loader |
| Darren Ryan | Video Assist Operator |
| Justine Chevalier | Wardrobe Assistant |
| Matt Kennedy | Visual Effects Production Assistant |
| Scott Bebe | Negative Cutter |
| Christine Leaman | Assistant Location Manager |
| Kyle Villegas | Location Coordinator |
| Michael A. Rizzo | Key Production Assistant |
| Larissa Grudt | Key Set Production Assistant |
| Hernando Bansuelo | Production Assistant |
| Kathryn Moïse | Production Secretary |
| Liz A. Randall | Technical Advisor |
| Jennifer DeLia | Travel Coordinator |
