 | Amy Adams als Margaret Keane |
 | Christoph Waltz als Walter Keane |
 | Danny Huston als Dick Nolan |
 | Jon Polito als Enrico Banducci |
 | Krysten Ritter als Dee-Ann |
 | Jason Schwartzman als Ruben |
 | Terence Stamp als John Canaday |
 | Madeleine Arthur als Older Jane |
 | Delaney Raye als Young Jane |
 | James Saito als Judge |
 | Farryn VanHumbeck als Lily |
| Guido Furlani als Dino Olivetti |
 | Elisabetta Fantone als Olivetti Girl |
 | Emily Maddison als 2nd Olivetti Girl |
 | Brent Chapman als Factory Boss |
 | Gabe Khouth als Dad at Art Show |
 | Dylan Kingwell als Boy at Art Show |
 | Peter Kelamis als Real Estate Guy |
 | Deni DeLory als Fancy Lady |
 | Desiree Zurowski als Tipsy Lady |
 | Vincent Gale als Tipsy Man |
 | Fred Keating als Priest |
 | Byron Bertram als Bathroom Man |
 | Heather Doerksen als Gossipy Woman #1 |
 | Eliza Norbury als Gossipy Woman #2 |
 | Ryan Beil als Nosy Gallery Guy |
 | Frenchy Gagne als Henri the Maitre'd |
 | Fiona Vroom als Gallery Assistant |
 | Jill Morrison als Gallery Patron |
 | Leela Savasta als Hippie Chick |
| Linda Sato als Jehovah's Witness #1 |
 | Traci Toguchi als Jehovah's Witness #2 |
 | Stephanie Bennett als Coed #1 |
| Andrea Bucko als Coed #2 |
| Emily Fonda als Sexy Girl |
 | Aaron Craven als Early Buyer |
| Lear Howard als Proper Woman |
| Heather Ireland als Proper Woman |
| Linda Marr als Proper Woman |
| Doreen McKenzie als Proper Woman |
| Elizabeth Urrea als Proper Woman |
 | Kari-Ann Wood als Female Art Gallery Attendee |
 | Dale Wolfe als TV Host |
 | Patricia Mayen-Salazar als Fan #1 |
 | Tony Alcantar als Fan #2 |
 | Darren Dolynski als Snobby Artist #1 |
 | David Milchard als Snobby Artist #2 |
 | Andrew Airlie als Rich Man |
| Forbes Angus als Civic Leader |
 | Michael Kopsa als NY Society Man |
 | Alan MacFarlane als Society Man #1 |
 | Thomas Potter als Society Man #2 |
 | Colleen Winton als Mrs. Teasdale |
 | Pomaika'i Brown als Radio DJ |
 | Dan Cooke als Reporter #1 |
 | L.G. Michael Brown als Reporter #2 |
 | Barclay Hope als Gannett Lawyer |
 | Mia Adams als Autograph Seeker |
 | Michael St. John Smith als Margaret's Lawyer |
 | Timothy Van Cleave als Cal Tjader |
 | Eric Keenleyside als Gannett Lawyer #2 |
 | Greg Kean als Gannett Lawyer #3 |
 | Sean Campbell als Bailiff |
| Julie Johnson als Hungry i Patron |
 | Britt Irvin als Hipster Lady |
 | Matthew Kevin Anderson als Hipster Man |
| Larry Karaszewski | Writer |
| Tim Burton | Producer |
| Lynette Howell Taylor | Producer |
| Tim Burton | Director |
| Scott Alexander | Producer |
| Larry Karaszewski | Producer |
| Katterli Frauenfelder | Executive Producer |
| Derek Frey | Executive Producer |
| Jamie Patricof | Executive Producer |
| Bob Weinstein | Executive Producer |
| Harvey Weinstein | Executive Producer |
| Bruno Delbonnel | Director of Photography |
| Scott Alexander | Writer |
| Colleen Atwood | Costume Design |
| Rick Heinrichs | Production Design |
| Chris August | Supervising Art Director |
| Shane Vieau | Set Decoration |
| Danny Elfman | Original Music Composer |
| Jeanne McCarthy | Casting |
| Nicole Abellara Hallman | Casting |
| JC Bond | Editor |
| Brendan Ferguson | Unit Production Manager |
| Katterli Frauenfelder | First Assistant Director |
| David Klohn | Second Assistant Director |
| Gordon Piper | Second Assistant Director |
| Brendan Ferguson | Line Producer |
| Tommy Harper | Consulting Producer |
| Coreen Mayrs | Locale Casting Director |
| Heike Brandstatter | Locale Casting Director |
| Scott Nicholson | Stunt Coordinator |
| Rocky Capella | Stunt Coordinator |
| Dan Redford | Stunt Double |
| Shaun Magee | Stunt Double |
| Melissa R. Stubbs | Stunt Driver |
| Krista Bell | Stunts |
| Janene Carleton | Stunts |
| Tammy Nera | Stunts |
| Tiffani Timms | Stand In |
| Michael Cound | Stand In |
| Gabriella Kriss | Stand In |
| Ricardo Sandoval | Assistant Art Director |
| James Philpott | Assistant Art Director |
| Michael Toby | Set Designer |
| Cheryl Marion | Set Designer |
| Nadine Sekora | Art Department Coordinator |
| Natalie Van Hest | Art Department Assistant |
| Des Whelan | "A" Camera Operator |
| Paul Guenette | First Assistant "A" Camera |
| Steve Krasznai | Second Assistant "A" Camera |
| David Crone | "B" Camera Operator |
| David Crone | Steadicam Operator |
| David Lourie | First Assistant "B" Camera |
| Rodrigo Carcamo Parga | Second Assistant "B" Camera |
| Leah Gallo | Still Photographer |
| Simon Jori | Digital Imaging Technician |
| Andrew W. Davidson | Chief Lighting Technician |
| Finn King | Key Grip |
| Chris Duesterdiek | Sound Mixer |
| Jon Lavender | Boom Operator |
| Tim Crich | Cableman |
| Justin Johns | Video Assist Operator |
| Susan Lambie | Script Supervisor |
| Jessie Thiele | Post Production Supervisor |
| Melody Gehrman | First Assistant Editor |
| Alex Anstey | First Assistant Editor |
| Michael Semanick | Sound Re-Recording Mixer |
| Tom Johnson | Sound Re-Recording Mixer |
| Oliver Tarney | Supervising Sound Editor |
| Bjørn Ole Schroeder | Supervising Sound Editor |
| James Harrison | Sound Effects Editor |
| Rob Killick | Dialogue Editor |
| Hugo Adams | Foley Editor |
| Nick Del-Molino | Assistant Sound Editor |
| Mark Taylor | Additional Sound Re-Recording Mixer |
| Paul Massey | Additional Sound Re-Recording Mixer |
| Michael Higham | Music Consultant |
| Peter Clarke | Music Editor |
| Michael Connell | Music Editor |
| Donna O'Neal | Key Costumer |
| Jennifer Grossman | Costume Supervisor |
| Carolyn Bentley | Set Supervisor |
| Jody Leanne Petford | Set Costumer |
| Judith Feller | Costumer |
| Lana S. Krause | Costumer |
| Victoria Down | Makeup Department Head |
| Connie Parker | Makeup Department Head |
| Gitte Axen | First Assistant Makeup Artist |
| Vanessa Giles | First Assistant Makeup Artist |
| Sanna Seppanen | Hair Department Head |
| Codey Blair | Hairstylist |
| Diane Holme | Hairstylist |
| Nicole Oguchi | Production Coordinator |
| Sharon Mosley | Additional Hairstylist |
| Sharon Markell | Additional Hairstylist |
| Roy Sidick | Additional Hairstylist |
| Danna Rutherford | Additional Hairstylist |
| Lisa Leonard | Additional Hairstylist |
| Jill Winston | Additional Hairstylist |
| Pauline L. Tremblay | Additional Hairstylist |
| Sigrid Spade | Assistant Set Decoration |
| Michael Church | Leadman |
| Shannon Gottlieb | Set Decoration Buyer |
| Elizabeth Roberts | Set Decoration Buyer |
| Lana Del Rey | Songs |
