 | Viggo Mortensen als Nikolai Luzhin |
 | Naomi Watts als Anna Ivanovna Khitrova |
 | Vincent Cassel als Kirill |
 | Armin Mueller-Stahl als Semyon |
 | Sinéad Cusack als Helen |
 | Donald Sumpter als Yuri |
 | Jerzy Skolimowski als Stepan |
 | Josef Altin als Ekrem |
 | Mina E. Mina als Azim |
 | Aleksandar Mikic als Soyka |
 | Sarah-Jeanne Labrosse als Tatiana |
 | Tatiana Maslany als Tatiana (voice) |
 | Tereza Srbova als Kirilenko |
 | David Papava als Chechen |
 | Tamer Hassan als Chechen |
 | Raza Jaffrey als Doctor Aziz |
 | Elisa Lasowski als Prostitute |
 | Alice Henley als Prostitute |
 | Tony Cook als Football Hooligan (uncredited) |
| David Cronenberg | Director |
| Steven Knight | Screenplay |
| Robert Lantos | Producer |
| Paul Webster | Producer |
| Howard Shore | Original Music Composer |
| Stephen Garrett | Executive Producer |
| David M. Thompson | Executive Producer |
| Jeff Abberley | Executive Producer |
| Julia Blackman | Executive Producer |
| Peter Suschitzky | Director of Photography |
| Carol Spier | Production Design |
| Ronald Sanders | Editor |
| Denise Cronenberg | Costume Design |
| Tracey Seaward | Co-Producer |
| Deirdre Bowen | Casting |
| Nina Gold | Casting |
| Judy Farr | Set Decoration |
| Mary-Lou Green-Benvenuti | Hairstylist |
| Christine Blundell | Makeup Artist |
| Charmaine Fuller | Makeup Artist |
| Catherine Palmer | Assistant Art Director |
| Robert J. Dugdale | Scenic Artist |
| David Packard | Scenic Artist |
| Paul Sacco | Dolby Consultant |
| Wayne Griffin | Supervising Sound Editor |
| Michael O'Farrell | Supervising Sound Editor |
| Rob Bertola | Sound Effects Editor |
| Orest Sushko | Sound Re-Recording Mixer |
| Mark Zsifkovits | Sound Re-Recording Mixer |
| Fiona Campbell Westgate | Visual Effects Producer |
| Aaron Weintraub | Visual Effects Supervisor |
| Paul Herbert | Stunt Coordinator |
| Alf Tramontin | Steadicam Operator |
| Roger Tooley | Steadicam Operator |
| Peter Mountain | Still Photographer |
| Jennifer Dunnington | Music Editor |
| David Broder | Location Manager |
| Susanna Lenton | Script Supervisor |
| Camilla Stephenson | Location Manager |
| Prudence Emery | Unit Publicist |
| Nick Palmer | Supervising Art Director |
| Rebecca Holmes | Art Direction |
| Bruce Bigg | Property Master |
| Lucy Allen | Stunts |
| Julian Spencer | Stunt Coordinator |
| Tony Currie | Dialogue Editor |
| Alastair Gray | Dialogue Editor |
| Andy Malcolm | Foley Artist |
| Goro Koyama | Foley Artist |
| Nick Iannelli | Digital Intermediate Producer |
| Dave Muscat | Digital Intermediate Editor |
