 | Michael Sheen als David Frost |
 | Frank Langella als Richard Nixon |
 | Kevin Bacon als Jack Brennan |
 | Sam Rockwell als James Reston Jr. |
 | Matthew Macfadyen als John Birt |
 | Oliver Platt als Bob Zelnick |
 | Rebecca Hall als Caroline Cushing |
 | Toby Jones als Swifty Lazar |
 | Andy Milder als Frank Gannon |
 | Kate Jennings Grant als Diane Sawyer |
 | Gabriel Jarret als Ken Khachigian |
 | Jim Meskimen als Ray Price |
 | Patty McCormack als Pat Nixon |
 | Geoffrey Blake als Interview Director |
 | Clint Howard als Lloyd Davis |
 | Rance Howard als Ollie |
 | Gavin Grazer als White House Director |
 | Simon James als Frost Show Director |
 | Eloy Casados als Manolo Sanchez |
 | Jay White als Neil Diamond |
| Wil Albert als Sammy Cahn |
 | Keith MacKechnie als Marv Minoff |
| Penny L. Moore als Lady with Dachshund |
 | Mark Simich als Hugh Hefner |
 | Janneke Williamson als Frost's Female Assistant |
 | Jenn Gotzon Chandler als Tricia Nixon |
 | Yvette Rachelle als Farrah Fawcett |
| Ron Howard | Director |
| Peter Morgan | Screenplay |
| Hans Zimmer | Original Music Composer |
| Daniel P. Hanley | Editor |
| Mike Hill | Editor |
| Salvatore Totino | Director of Photography |
| Daniel Orlandi | Costume Design |
| Jane Jenkins | Casting |
| Janet Hirshenson | Casting |
| Michael Corenblith | Production Design |
| Susan Benjamin | Set Decoration |
| Sherry Gallarneau | Script Supervisor |
| Ralph Nelson Jr. | Still Photographer |
| Andrew Rowlands | Steadicam Operator |
| Daniel R. Purinton | Rigging Gaffer |
| Rick Avery | Stunt Coordinator |
| Kathy Nelson | Music Supervisor |
| Daniel Pinder | Music Editor |
| Eric Fellner | Producer |
| Brian Grazer | Producer |
| Ron Howard | Producer |
| Tim Bevan | Producer |
| William M. Connor | Associate Producer |
| Louisa Velis | Associate Producer |
| Kathleen McGill | Associate Producer |
| Liza Chasin | Executive Producer |
| Matthew Byam-Shaw | Executive Producer |
| Karen Kehela Sherwood | Executive Producer |
| Debra Hayward | Executive Producer |
| Peter Morgan | Theatre Play |
| Peter Morgan | Executive Producer |
| David Bernardi | Executive Producer |
| Todd Hallowell | Executive Producer |
| Michelle Brattson | Production Supervisor |
| Kathleen McGill | Unit Production Manager |
| Kim Santantonio | Hair Department Head |
| Edouard F. Henriques | Makeup Department Head |
| Natasha Allegro | Key Hair Stylist |
| Merribelle Anderson | Hairstylist |
| Colleen Callaghan | Hairstylist |
| Karyn Huston | Hairstylist |
| Linda Leiter Sharp | Hairstylist |
| Robin Beauchesne | Makeup Artist |
| Elizabeth Hoel-Chang | Makeup Artist |
| Sabine Roller | Makeup Artist |
| Greg Funk | Makeup Artist |
| Brian Avery | Stunts |
| Martin Charles | Graphic Designer |
| Patrick Tendai Pfupajena | Production Assistant |
