 | Bob Hope als Humphrey "Sorrowful" Jones |
 | Lucille Ball als Gladys O'Neill |
 | William Demarest als Regret |
 | Bruce Cabot als Big Steve Holloway |
 | Thomas Gomez als Reardon |
 | Tom Pedi als Once Over Sam |
 | Paul Lees als Orville Smith |
 | Houseley Stevenson als Doc Chesley |
 | Ben Welden als Big Steve's Bodyguard |
 | Emmett Vogan als Psychiatrist |
 | Mary Jane Saunders als Martha Jane Smith |
 | Erville Alderson als Happy the Mortician (uncredited) |
| Ethel Bryant als Nurse (uncredited) |
| John Butler als Jack, Bettor on Green Demon (uncredited) |
 | Claire Carleton als Agnes 'Happy Hips' Noonan (uncredited) |
| Douglas Carter als Horse Player (uncredited) |
| Bill Cartledge als First Jockey (uncredited) |
 | Maurice Cass als Psychiatrist (uncredited) |
| George Chan als Chinese Man (uncredited) |
 | Noble 'Kid' Chissell als Bookie (uncredited) |
| Michael Cirillo als Horse Player (uncredited) |
| Tony Cirillo als Horse Player (uncredited) |
| Charles Cooley als Shorty (uncredited) |
| James Cornell als Horse Player (uncredited) |
| Betty Corner als Nurse (uncredited) |
 | Edgar Dearing als Police Lt. Ed Mitchell (uncredited) |
 | Sayre Dearing als Spectator (uncredited) |
 | Jay Eaton als Horse Player (uncredited) |
| Sam Finn als Horse Player (uncredited) |
| Joe Gray als Gambler (uncredited) |
 | Chuck Hamilton als Policeman (uncredited) |
| Henry Hope als Motorcyclist (uncredited) |
| Jerry Hunter als Newsboy (uncredited) |
 | Selmer Jackson als Doctor (uncredited) |
 | Kenner G. Kemp als Bookmaker (uncredited) |
 | Bob Kortman als Horse Player (uncredited) |
 | Marc Krah als Nick, the Barber (uncredited) |
| Pat Lane als Bookie (uncredited) |
 | Orley Lindgren als Bit Part (uncredited) |
 | Louise Lorimer als Nurse-Receptionist (uncredited) |
 | George Magrill als Horse Player (uncredited) |
| John Mallon als Horse Player (uncredited) |
| Speer Martin als Jockey (uncredited) |
 | John "Skins" Miller als Head Telephone Man (uncredited) |
| Ralph Montgomery als Horse Player (uncredited) |
| Patsy O'Byrne als Mrs. Oliver Sims (uncredited) |
 | Ralph Peters als Taxicab Driver (uncredited) |
| Dario Piazza als Horse Player (uncredited) |
| Sally Rawlinson als Nurse (uncredited) |
| Allen Ray als Horse Player (uncredited) |
 | Suzanne Ridgway als Nightclub Patron (uncredited) |
| Eddie Rio als Bookie (uncredited) |
| Jack Roberts als Horse Player (uncredited) |
| John Shay als Doctor (uncredited) |
| Billy Snyder als Bookie (uncredited) |
 | Arthur Space als Plainclothes Policeman (uncredited) |
 | Bert Stevens als Nightclub Patron (uncredited) |
| Delmar Thomas als Exercise Boy (uncredited) |
 | Sid Tomack als Waiter at Steve's Place (uncredited) |
 | Harry Tyler als Blinky (uncredited) |
 | Annette Warren als Gladys O'Neill (singing voice) (uncredited) |
 | Walter Winchell als Himself (voice) (uncredited) |
| William Yip als Bookie (uncredited) |
 | Frank Mills |
| James Davies |
| Sidney Lanfield | Director |
| Edmund L. Hartmann | Screenplay |
| Damon Runyon | Story |
| Melville Shavelson | Screenplay |
| Jack Rose | Screenplay |
| Daniel L. Fapp | Director of Photography |
| Hans Dreier | Art Direction |
| Albert Nozaki | Art Direction |
| Gordon Jennings | Special Effects |
| Sam Comer | Set Decoration |
| Bertram C. Granger | Set Decoration |
| Robert Emmett Dolan | Original Music Composer |
| Arthur P. Schmidt | Editor |
| Mary Kay Dodson | Costume Design |
| Wally Westmore | Makeup Supervisor |
| Oscar Rudolph | Assistant Director |
| Jay Livingston | Songs |
| Ray Evans | Songs |
| Harold Lewis | Sound Recordist |
| John Cope | Sound Recordist |
| Robert L. Welch | Producer |
