 | Kate Beckinsale als Carrie Stetko |
 | Gabriel Macht als Robert Pryce |
 | Tom Skerritt als Dr. John Fury |
 | Columbus Short als Delfy |
 | Shawn Doyle als Sam Murphy |
 | Alex O'Loughlin als Russell Haden |
 | Joel S. Keller als Jack |
 | Jesse Todd als Rubin |
 | Arthur Holden als McGuire |
| Erin Hickock als Rhonda |
 | Bashar Rahal als Russian Pilot |
| Julian Cain als Russian Co-pilot |
 | Dennis Keiffer als Russian Guard |
 | Andrei Runtso als Russian Guard |
 | Roman Varshavsky als Russian Guard |
 | Steve Lucescu als Mooney |
 | Paula Jean Hixson als Lab Tech |
 | Marc James Beauchamp als Weiss |
 | Sean Tucker als Operations Tech |
 | Patrick Sabongui als Miami Prisoner |
| Dominic Sena | Director |
| Jon Hoeber | Screenplay |
| Erich Hoeber | Screenplay |
| Chad Hayes | Screenplay |
| Carey Hayes | Screenplay |
| John Frizzell | Music |
| Martin Hunter | Editor |
| Christopher Soos | Director of Photography |
| Steve Richards | Executive Producer |
| Don Carmody | Executive Producer |
| Greg Rucka | Executive Producer |
| Joel Silver | Producer |
| Susan Downey | Producer |
| David Gambino | Producer |
| Mary Gail Artz | Casting |
| Shani Ginsberg | Casting |
| Andrea Kenyon | Casting |
| Randi Wells | Casting |
| Graham 'Grace' Walker | Production Design |
| Gilles Aird | Art Direction |
| Martin Gendron | Art Direction |
| Jean Kazemirchuk | Art Direction |
| Réjean Labrie | Set Decoration |
| Wendy Partridge | Costume Design |
| Bridget O'Neill | Makeup Department Head |
| Rachel Parkin | Costume Supervisor |
| Harold Parker | First Assistant Editor |
| Kevin Kaska | Orchestrator |
| Lorette Leblanc | Script Supervisor |
| Carrie Foster | Art Department Coordinator |
| Alain Brochu | Construction Coordinator |
| Alp Altiner | Visual Effects Art Director |
| Phillip Tellez | Construction Coordinator |
| Denis Hamel | Property Master |
| Louis Craig | Special Effects Supervisor |
| Pierre 'Bill' Rivard | Special Effects Coordinator |
| John E. Gray | Special Effects Coordinator |
| Peter Dydo | Animation |
| Clement Yip | Animation |
| Seth Lippman | CG Supervisor |
| Wojciech Zielinski | CG Supervisor |
| Colin Laski | Digital Effects Supervisor |
| Wendy Hulbert | Visual Effects Coordinator |
| Safia Siad | Visual Effects Coordinator |
| Matt Magnolia | Visual Effects Coordinator |
| Matt Daly | Visual Effects Coordinator |
| Sarah Barber | Visual Effects Coordinator |
| Myléne Guérin | Visual Effects Coordinator |
| Anouk L'Heureux | Visual Effects Coordinator |
| Martine Losier | Visual Effects Coordinator |
| Anouk Deveault-Moreau | Visual Effects Coordinator |
| Alessandra Carlino | Visual Effects Editor |
| Bernardo Rodriguez | Visual Effects Editor |
| Branden Bratuhin | Visual Effects Editor |
| David Sanger | Visual Effects Producer |
| Daniel Leduc | Visual Effects Producer |
| Sarah McMurdo | Visual Effects Producer |
| Tavia Charlton | Visual Effects Producer |
| Dennis Berardi | Visual Effects Supervisor |
| Ian Hunter | Visual Effects Supervisor |
| Richard Yuricich | Visual Effects Supervisor |
| Jeff Goldman | Visual Effects Supervisor |
| Richard Martin | Visual Effects Supervisor |
| Tom Turnbull | Visual Effects Supervisor |
| Thierry Delattre | Visual Effects Supervisor |
| Val Kharitonashvili | Visual Effects Technical Director |
| Hans Bjerno | Aerial Director of Photography |
| Jeremy Braben | Aerial Director of Photography |
| Tim Merkel | Camera Operator |
| Robert Stecko | Camera Operator |
| Tony Cutrono | Second Unit Director of Photography |
| Eames Gagnon | Gaffer |
| Victor Abbene | Gaffer |
| Gilles Fortier | Rigging Gaffer |
| Jean-François Dubé | Rigging Grip |
| François Perrier | Steadicam Operator |
| Rafy | Still Photographer |
| Richard Boucher | Techno Crane Operator |
| Stéphane Byl | Lighting Technician |
| W. James Meagher | Lighting Technician |
| Nicolas Phillips | Lighting Technician |
| Jim Filippone | Pilot |
| Stephanie Girard Hamelin | Video Assist Operator |
| Larissa Mair | Casting Associate |
| Freya Krasnow | Casting Assistant |
| Heather Moore | Assistant Costume Designer |
| Jim Eberle | Digital Intermediate |
| Erik Rogers | Digital Intermediate |
| Stefan Sonnenfeld | Digital Intermediate |
| Christopher Hills-Wright | First Assistant Editor |
| Jason Wasserman | First Assistant Editor |
| Jim Harrison | Music Editor |
| Derek Somaru | Music Editor |
| Ian Neil | Music Supervisor |
| Nadia Guglieri | Script Supervisor |
| Petra Jorgensen | Script Supervisor |
| Susan Bambara | Script Supervisor |
| Stephanie Flack | ADR Supervisor |
| Louis Piché | Boom Operator |
| Gerard Vernice | Boom Operator |
| Cliff Latimer | Dialogue Editor |
| Vincent Guisetti | Foley |
| Pamela Kahn | Foley |
| Nancy Parker | Foley |
| Marla McGuire | Foley Editor |
| Christopher Alba | Foley |
| Zack Allen | Sound Effects Editor |
| Dane A. Davis | Sound Effects Editor |
| Tom Ozanich | Sound Effects Editor |
| David A. Whittaker | Sound Effects Editor |
| Eric Lindemann | Sound Effects Editor |
| Greg Hedgepath | Sound Effects Editor |
| Gregg Rudloff | Sound Re-Recording Mixer |
| John T. Reitz | Sound Re-Recording Mixer |
| Mark Larry | Supervising Sound Editor |
| Teressa Hill | Hair Department Head |
| Corald Giroux | Key Hair Stylist |
| Marie-Josée Binette | Hairstylist |
| Gaétan Landry | Hairstylist |
| Ghislaine Sant | Hairstylist |
| Erik Gosselin | Key Makeup Artist |
| Christophe Giraud | Makeup Artist |
| Kathy Kelso | Makeup Artist |
| Brenda Magalas | Makeup Artist |
| Doug Morrow | Makeup Artist |
| Amanda Kuryk | Makeup Artist |
| Magali Métivier | Makeup Artist |
| Vasilios Tanis | Makeup Artist |
| Ronald Gilbert | Production Manager |
| Deb LeFaive | Production Manager |
| Stuart Baird | Additional Editor |
| Colin Follenweider | Stunt Double |
| Marie France Denoncourt | Stunt Double |
| Karine Lemieux | Stunt Double |
| Nathalie Girard | Stunt Double |
| Sarah Murphy-Dyson | Stunt Double |
| Greg Rucka | Graphic Novel |
| Brian Smrz | Second Unit Director |
| Edward A. Queffelec | Stunt Double |
| Dan Skene | Stunts |
| Mark Aaron Wagner | Stunts |
| Patrick Kerton | Stunt Double |
| Stéphane Julien | Stunts |
| Jere Gillis | Stunt Double |
| Steve Lucescu | Stunt Coordinator |
| Bill Leaman | Stunt Double |
| Patrick Sabongui | Stunts |
| Christopher McGuire | Stunt Double |
| Kevin Yeboah | Stunts |
