 | Montgomery Clift als George Eastman |
 | Elizabeth Taylor als Angela Vickers |
 | Shelley Winters als Alice Tripp |
 | Anne Revere als Hannah Eastman |
 | Keefe Brasselle als Earl Eastman |
 | Fred Clark als Defense Attorney Bellows |
 | Raymond Burr als District Attorney R. Frank Marlowe |
 | Herbert Heyes als Charles Eastman |
 | Shepperd Strudwick als Anthony Vickers |
 | Frieda Inescort als Mrs. Ann Vickers |
 | Kathryn Givney als Louise Eastman |
 | Walter Sande als Defense Attorney Art Jansen |
 | Ted de Corsia als Judge R.S. Oldendorff |
 | John Ridgely als Coroner |
 | Lois Chartrand als Marsha |
 | Paul Frees als Reverend Morrison |
 | Robert J. Anderson als Eagle Scout (uncredited) |
 | Gertrude Astor als Bit Part (uncredited) |
| Frances Curry als Vickers' Maid Lulu (uncredited) |
 | Franklyn Farnum als Company Executive (uncredited) |
 | Bess Flowers als Courtroom Reporter (uncredited) |
 | Kathleen Freeman als Factory Worker - Prosecution Witness (uncredited) |
| Art Gilmore als Radio Broadcaster (voice) (uncredited) |
 | Kenner G. Kemp als Courtroom Spectator (uncredited) |
| Mary Kent als Alice's Landlady Mrs. Roberts (uncredited) |
| Mike Mahoney als Motorcycle Officer (uncredited) |
 | Hank Mann als Courtroom Spectator (uncredited) |
 | Harold Miller als (uncredited) |
 | William H. O'Brien als Servant at Eastman's Party (uncredited) |
 | Frank O'Connor als Factory Floorman (uncredited) |
 | Kasey Rogers als Miss Harper (uncredited) |
 | Douglas Spencer als Boatkeeper (uncredited) |
 | Larry Steers als Company Executive (uncredited) |
 | Arthur Tovey als Juror (uncredited) |
 | Dorothy Vernon als Courtroom Spectator (uncredited) |
 | Josephine Whittell als Eastman's Secretary Margaret (uncredited) |
| Eric Wilton als Vickers' Butler (uncredited) |
 | Ian Wolfe als Dr. Wyeland (uncredited) |
| Frank Yaconelli als Truck Driver (uncredited) |
| Ezelle Poule als Receptionist (uncredited) |
| Harry Brown | Screenplay |
| George Stevens | Director |
| Michael Wilson | Screenplay |
| Theodore Dreiser | Novel |
| Loyal Griggs | Other |
| William Hornbeck | Editor |
| Gordon Jennings | Special Effects |
| Farciot Edouart | Other |
| William C. Mellor | Director of Photography |
| George Stevens | Producer |
| Franz Waxman | Original Music Composer |
| Ivan Moffat | Associate Producer |
| Fred Guiol | Other |
| Howie Horwitz | Other |
| Hans Dreier | Art Direction |
| Emile Kuri | Set Decoration |
| Edith Head | Costume Design |
| Charles C. Coleman | Assistant Director |
| Wally Westmore | Makeup Department Head |
| Walter H. Tyler | Art Direction |
| Gene Merritt | Sound Recordist |
| Gene Garvin | Sound Recordist |
| Patrick Kearney | Theatre Play |
| Polly Burson | Stunt Double |
| Helen Thurston | Stunt Double |
| Paul Baxley | Stunt Double |
