 | Robert Redford als Bill Bryson |
 | Nick Nolte als Stephen Katz |
 | Emma Thompson als Catherine Bryson |
 | Nick Offerman als REI Dave |
 | Kristen Schaal als Mary Ellen |
 | Chrystee Pharris als Ticket Agent |
 | Sandra Ellis Lafferty als Widow Deborah |
 | Hayley Lovitt als Donna |
 | Derek Krantz als Young Hiker #2 |
 | Andrew Vogel als Young Hiker #1 |
| Linds Edwards als Darren |
 | R. Keith Harris als Sam Bryson |
| John Kap als Bealuh's Husband |
 | Mary Steenburgen als Jeannie |
 | Randall Newsome als TV Host |
| Susan McPhail als Beulah |
| Gaia Wise als Becca |
 | Tucker Meek als Grandson |
 | Chandler Head als Granddaughter |
 | John Schmedes als Gene |
 | Danny Vinson als Georgia Cab Driver |
 | Valerie Payton als Waitress Raynette |
 | Stephanie Astalos-Jones als Georgia Mountain Waitress |
 | Kevin Harrison als Southbound Hiker |
| Bridget Gethins als Campground Jensine |
 | Alex Van als Bunkhouse Peter |
 | Mimi Gould als Jeannie's Mother |
 | Rowan Bousaid als Rental Agent |
 | Njema Williams als Trail Head Taxi Driver |
 | Marcy Conway als Hiker in Bunk House (uncredited) |
| John Bailey | Director of Photography |
| Nathan Larson | Original Music Composer |
| Robert Redford | Producer |
| Carol Littleton | Editor |
| Brian McManus | Makeup Department Head |
| Ken Kwapis | Director |
| Gae S. Buckley | Production Design |
| Mike Moyer | Gaffer |
| Jeremiah Samuels | Executive Producer |
| Jeremiah Samuels | Unit Production Manager |
| Mark Fincannon | Casting |
| Ron Bochar | Supervising Sound Editor |
| Ron Bochar | Sound Re-Recording Mixer |
| Marko Costanzo | Foley |
| David Fletcher | Special Effects Coordinator |
| Julie Garcés | Editor |
| Susan Jacobs | Music Supervisor |
| Bill Bryson | Author |
| Leigh Leverett | Costume Design |
| Bill Holderman | Screenplay |
| Bill Holderman | Producer |
| Stephen P. Dunn | First Assistant Director |
| Damiana Kamishin | Production Supervisor |
| Philip Stockton | Dialogue Editor |
| Frank Masi | Still Photographer |
| Brian Reali | Digital Intermediate |
| John Heller | Visual Effects Supervisor |
| Joani Yarbrough | Key Hair Stylist |
| Park Jae-wook | Visual Effects Supervisor |
| E. Aaron Linker | Set Designer |
| Laine Trzinski | Hair Department Head |
| Rick Kerb | Screenplay |
| Richard Roles | Helicopter Camera |
| Rob Simons | Art Direction |
| Erika Abrams | Visual Effects Producer |
| Tim Weber | Visual Effects Coordinator |
| Jennifer R. Blair | Art Department Coordinator |
| Jeff Crumbley | Camera Operator |
| Lynne Mitchell | Set Decoration |
| Jamie Archer | Construction Coordinator |
| Benjamin Spek | Camera Operator |
| Benjamin Spek | Steadicam Operator |
| David Shakibanasab | Rigging Gaffer |
| Dana Salerno | Casting Associate |
| Danielle Stammers | Set Costumer |
| Katherine Steets | Script Supervisor |
| Amber Crowe | Makeup Artist |
| Freddy Chancellor | Boom Operator |
| Jason Davis | Property Master |
