 | Denzel Washington als Detective Keith Frazier |
 | Clive Owen als Dalton Russell |
 | Jodie Foster als Madeleine White |
 | Christopher Plummer als Arthur Case |
 | Willem Dafoe als Captain John Darius |
 | Chiwetel Ejiofor als Detective Bill Mitchell |
 | Carlos Andrés Gómez als Steve |
 | Kim Director als Stevie |
 | James Ransone als Steve-O |
 | Bernie Rachelle als Chaim |
 | Peter Gerety als Captain Coughlin |
 | Victor Colicchio als Sergeant Collins |
 | Cassandra Freeman als Sylvia |
 | Peter Frechette als Peter Hammond |
 | Gerry Vichi als Herman Gluck |
 | Waris Ahluwalia als Vikram Walia |
 | Rafael Osorio als Bank Guard |
 | Rodney "Bear" Jackson als Bank Guard |
 | Daryl Mitchell als Mobile Command Officer Rourke |
 | Ashlie Atkinson als Mobile Command Officer Berk |
 | David Brown als Mobile Command Officer Carnow |
 | Robert C. Kirk als Mobile Command Officer Borinsky |
 | Frank Stellato als Mobile Command Detective |
 | Ken Leung als Wing |
 | Marcia Jean Kurtz als Miriam Douglas |
| Ed Onipede Blunt als Ray Robinson |
 | Amir Ali Said als Brian Robinson |
| Lemon Andersen als Paul Guitierez |
 | Samantha Ivers als Nancy Mann |
| Peter Kybart als Mayor |
 | Al Palagonia als Kevin |
| Florina Petcu als Ilina Miritia |
 | Jason Manuel Olazabal als ESU Officer Hernandez |
 | Jeff Ward als ESU Officer Jesus |
 | Anthony Mangano als ESU Officer |
 | Michael Devine als ESU Officer |
| Ed Bogdanowicz als ESU Officer |
| Aaron Vexler als ESU Officer |
| Anthony Borowiec als ESU Officer |
| Joe Coots als ESU Officer |
| Lionel Pina als Cop with Pizzas |
 | Ken Ferrigni als Redheaded Detective |
| Frank Hopf als Barricade Officer |
| Robert Testut als Barricade Officer |
| Craig M. Spitzer als Seth Greenblatt |
 | Limary Agosto als Gladys Perez |
| Patrick Illig als Brad Stone |
| Frank Composto als Eric Dodge |
| Rozanne Sher als Hostage Woman |
| Rachel Black als Katherine |
 | Gregory Dann als Case's Bodyguard |
 | Ben Crowley als White's Assistant |
| Shon Gables als CBS News Reporter |
| Dominic Carter als NY1 News Anchor |
| Sandra Endo als NY1 News Reporter |
 | Kandiss Edmundson als Madge |
| Agim Coma als Borova |
 | John Speredakos als Porcario |
| Baktash Zaher als Zahir |
| Ernest Rayford als Men's Club Attendant |
| Vincent DiMartino als Barber |
| Julian Niccolini als Four Seasons Maître d' |
 | Ed Crescimanni als Edwin |
 | Brad Leland als Ronnie |
 | Michal Sinnott als Lori Minitte |
| Enver Hoxha als Self (archive sound) |
| Brian Grazer | Producer |
| Wynn Thomas | Production Design |
| Eugene Gearty | Sound Effects Designer |
| Jon Kilik | Executive Producer |
| Matthew Libatique | Director of Photography |
| Spike Lee | Director |
| Russell Gewirtz | Writer |
| Karen Kehela Sherwood | Executive Producer |
| Kim Roth | Executive Producer |
| Daniel M. Rosenberg | Executive Producer |
| Jonathan Filley | Unit Production Manager |
| Jonathan Filley | Co-Producer |
| Terence Blanchard | Original Music Composer |
| Barry Alexander Brown | Editor |
| Kim Taylor-Coleman | Casting |
| Donna Berwick | Costume Design |
| Rodney "Bear" Jackson | Second Second Assistant Director |
| David Boulton | ADR Engineer |
| Curtis Lindersmith | Digital Intermediate Editor |
| Randall Balsmeyer | Title Designer |
| Steven Kirshoff | Special Effects Supervisor |
| Chris Shriver | Art Direction |
| George DeTitta Jr. | Set Decoration |
| Sam Pollard | Additional Editing |
| Todd Bozung | Supervising Music Editor |
| Howard Drossin | Orchestrator |
| Marko Costanzo | Foley Artist |
| Chris Fielder | Assistant Sound Editor |
| Marissa Littlefield | ADR Editor |
| Anita Gibson | Key Makeup Artist |
| Fred Rosenberg | Dialogue Editor |
| Carla Meyer | Dialect Coach |
| Mike Phillips | Production Accountant |
| Mike Ellis | First Assistant Director |
| Eve Streger | Casting Assistant |
| Ryan Denmark | First Assistant Editor |
| Carmen Cárdenas | Art Department Production Assistant |
| Ricardo Sarmiento | Camera Operator |
| Paul A. Simmons Jr. | Costume Supervisor |
| Jeff Ward | Stunt Coordinator |
| Frank Kern | Foley Supervisor |
| Michael Saccio | Property Master |
| Philip Stockton | Supervising Sound Editor |
| Patricia Regan | Makeup Artist |
| James C. Feng | Assistant Art Director |
| Sean Garnhart | Foley Mixer |
| Stephen Consentino | Steadicam Operator |
| Stephen Consentino | "A" Camera Operator |
| Leann Murphy | Art Department Coordinator |
| Bill Almeida | Rigging Gaffer |
| Alex Jablonski | Assistant Editor |
| Martin Bernstein | Construction Coordinator |
| Bob Chefalas | Additional Sound Re-Recording Mixer |
| John G. Velez | Gaffer |
| Allan Zaleski | Sound Effects Editor |
| Fred Buchholz | Special Effects Assistant |
| Kenneth Walker | Key Hair Stylist |
| Shari L. Carpenter | Continuity |
| Linton Alfred | Stunts |
| Tsigie White | Costume Assistant |
| David Lee | Still Photographer |
| William Sarokin | Production Sound Mixer |
| Jamie Baker | Foley Editor |
| George Leong | Boom Operator |
| Darrin Smith | Best Boy Electric |
| Gene O'Neill | Transportation Captain |
| Kurt Rimmel | Dolly Grip |
| Diana E. Latham | Production Coordinator |
| Tony Arnaud | Grip |
| Lamont Crawford | Key Grip |
| Guy Efrat | Location Scout |
| Dan Maslen | Storyboard Artist |
| John Canavan | Transportation Co-Captain |
| Terrence Laron Burke | Best Boy Grip |
| Susan Lazarus | Post Production Supervisor |
| Beth Avery | Location Assistant |
| James Klotsas | Props |
| Ethan Borsuk | Assistant Camera |
| Miguel Ángel Poveda | Production Manager |
| Paul Tanzillo Jr. | Negative Cutter |
| Joseph White | Location Manager |
| Careen Fowles | Costumer |
| Devin Maggio | Special Effects Technician |
| Pyare Fortunato | First Assistant Camera |
| Ryder Washburn | Armorer |
| Meg Thornton | Ager/Dyer |
| Colin Cumberbatch | Production Supervisor |
| Carlie Bergman | ADR Recordist |
| Gabu Camilo | Set Dresser |
| Kim Jackson | Assistant Production Coordinator |
| Pierson Silver | Camera Loader |
| Yana Collins Lehman | Post Production Accountant |
| Justin Panzanaro | Rigging Grip |
| Victoria Brown McCready | Payroll Accountant |
| Jean Chien | Assistant Location Manager |
| Terra Bliss | Digital Intermediate Producer |
| Vincent Guarriello | Key Construction Grip |
| Arne Olsen | Construction Grip |
| Dicken Berglund | ADR Mixer |
| Sara Stern | Apprentice Sound Editor |
| Colleen Morris-Glennon | Seamstress |
| Robert Antalocy | Carpenter |
| Dan DeTitta | Set Decoration Buyer |
| Laura Sewrey | Assistant Costume Designer |
| Timothy Main | Construction Foreman |
| Mark Adams | Musician |
| William Sepulveda | Craft Service |
| Evelyn Santana | Publicist |
| Nicholas Brown | Set Production Assistant |
| James Hook | Stand In |
| Jackie Bazan | Unit Publicist |
| Max Frankston | Video Assist Operator |
| Tracey Hinds | Second Assistant Director |
| Justin Cheatham | Electrician |
| Ross Huttick | Assistant Property Master |
| Allen Stillman | Shop Electric |
| James Parsons | Camera Production Assistant |
| Jeffrey L. Glave | Charge Scenic Artist |
| Ella Boliver | Digital Compositor |
| Mo Link | Extras Casting Assistant |
| Bridgett Brown | Intern |
| Jill Fazzolare | Production Assistant |
| Jennifer Gaston-Gates | Second Assistant Accountant |
