 | Bill Pullman als George Bailey |
 | Penelope Ann Miller als Mary Hatch Bailey |
 | Nathan Lane als Clarence |
 | Martin Landau als Pa Bailey / Mr. Potter |
 | Sally Field als Mrs. Bailey / Narrator |
 | Joe Mantegna als Joseph / Nick |
 | Christian Slater als Harry Bailey / Sam Wainwright |
 | Jerry Van Dyke als Uncle Billy |
 | Robert Guillaume als Mr. Gower |
 | Carol Kane als Cousin Tilly / Mrs. Hatch |
 | Bronson Pinchot als Mr. Carter |
 | Dan Lauria als Bert |
 | Craig Sheffer als Ernie Bishop / Ed / Bridgekeeper |
 | Armelia McQueen als Mrs. Thompson |
 | Ryan Slater als Young George Bailey / Peter Bailey |
 | Tina Majorino als Janie Bailey |
 | Myles Jeffrey als Tommy Bailey |
 | Mae Whitman als Zuzu Bailey |
 | Casey Kasem als Radio Announcer |
| Matthew Diamond | Director |
| James Arntz | Producer |
| Mary Jo Slater | Producer |
| Richard S. Kaufman | Music Supervisor |
| Barry Robison | Set Designer |
| John Retsek | Art Direction |
| Mary J. Danly | Editor |
| Bettina Bennewitz | Line Producer |
| Donald A. Morgan | Lighting Design |
| Dimitri Tiomkin | Original Music Composer |
| Roger Terracina | Technical Supervisor |
| Thomas Ware | Production Manager |
| Kathy Brisker | Production Coordinator |
| Gerald Zelinger | Sound |
| Ray Erlenborn | Sound Effects |
| Rob Drake | Property Master |
| Paul Basta | Camera Operator |
| Don Davis | Camera Operator |
| Hank Geving | Camera Operator |
| Victor Gonzalez | Camera Operator |
| Bob Highton | Camera Operator |
| Dave Hilmer | Camera Operator |
| Dan Webb | Camera Operator |
| Dean Kenworthy | Hairstylist |
| Denise Rossouw | Makeup Artist |
| Shutchai Tym Buacharern | Makeup Artist |
| Sarah Jones | Makeup Artist |
| Francesco Trulla | Makeup Artist |
| Kevin Leggett | Wardrobe Supervisor |
| Rachel Ehlers | Wardrobe Assistant |
| Kitty Rourke | Script Supervisor |
| Philip Van Doren Stern | Original Story |
| Blaine Baggett | Executive In Charge Of Production |
| Jimmy Hawkins | Executive Producer |
| Mary Mazur | Executive Producer |
