 | Namir Smallwood als Dr. James Hayman |
 | Sidney Flanigan als Helen Adso |
 | Michael Potts als Dr. Emil Harrison |
 | Rebecca Spence als Karen Adso |
 | Cheryl Lynn Bruce als Vivian Spurlock |
 | David Cromer als Mark |
| Max Lipchitz als Carol Hontolas |
 | Kelly O'Sullivan als Dr. Kayla Matthews |
 | Bradley Grant Smith als Dr. Mac Maclauren |
 | Charin Alvarez als Sam |
| Alex Thompson | Director |
| Alex Thompson | Writer |
| Christopher Thompson | Writer |
| Gianna Capra | Executive Producer |
| James Choi | Producer |
| Pierce Cravens | Producer |
| Neil Elman | Executive Producer |
| Leah Gaydos | Producer |
| Julianna Emel | Producer |
| Ian Keiser | Producer |
| Liv Krusinski | Executive Producer |
| Edwin Linker | Producer |
| Hannah Pillemer | Executive Producer |
| Fernando Szew | Executive Producer |
| Alex Thompson | Producer |
| Tony Vassiliadis | Executive Producer |
| Alex Wilson | Producer |
| Keaton Wooden | Producer |
| Michael Spencer Smith | Editor |
| Alexis Jade Links | Casting |
| Mickie Paskal | Casting |
| Jennifer Rudnicke | Casting |
| Luke Dyra | Gaffer |
| John R. Fisher | Special Effects |
| Rochelle Kneisely-Fisher | Special Effects Supervisor |
| Nick Fischer | Painter |
| John R. Fisher | Project Manager |
| John R. Fisher | Special Effects Makeup Artist |
| Rochelle Kneisely-Fisher | Sculptor |
| Rochelle Kneisely-Fisher | Special Effects Makeup Artist |
| Alexander Scarfe | Assistant Editor |
| Quinn Tsan | Original Music Composer |
| Nate Hurtsellers | Director of Photography |
| Matt Hyland | Production Design |
| Rachel Cole | Production Design |
