 | Heather Graham als Dr. Elizabeth Derby |
 | Judah Lewis als Asa Waite |
 | Bruce Davison als Ephraim Waite |
 | Johnathon Schaech als Edward Derby |
 | Barbara Crampton als Dr. Daniella Upton |
 | Graham Skipper als Pathologist |
 | Brett A. Newton als Professor Fisk |
 | Chris L. McKenna als Crawley |
 | J.D. Evermore als Detective Ledger |
 | Giovannie Cruz als Officer Huxley |
 | Ann Mahoney als Susan |
 | Hunter Womack als Mace, Jr. |
 | Jonah Ray als Dave the Orderly |
 | Joe Lynch als Ray the Orderly |
 | Drake Malone als Resident |
 | Kim Barnard als Nurse |
| Joe Lynch | Director |
| Barbara Crampton | Producer |
| Bob Portal | Producer |
| Joe Wicker | Producer |
| Inderpal Singh | Producer |
| Brian Yuzna | Executive Producer |
| Joe Lynch | Executive Producer |
| Rick Moore | Executive Producer |
| James Norrie | Executive Producer |
| Nina Kolokouri | Executive Producer |
| Dennis Paoli | Writer |
| H.P. Lovecraft | Short Story |
| David Guglielmo | Associate Producer |
| Morgan Peter Brown | Co-Producer |
| David Matthews | Director of Photography |
| David Guglielmo | Casting |
| Lily Bolles | Production Design |
| Sara Oliver | Art Direction |
| Dayton Douglass | Set Decoration |
| Amanda Bourne | Hair Department Head |
| Lea Enslin | Stunt Coordinator |
| Anny Kim | Makeup Department Head |
| Kim Barnard | First Assistant Director |
| Michael Bekemeier | Stunts |
| Lydia Hand | Stunts |
| Christopher C. Padilla | Stunts |
| Juan Pablo Saldarriaga Alaguna | Foley Editor |
| Maria Clara Calle | Foley Editor |
| David Crane | Sound Re-Recording Mixer |
| David Crane | Supervising Sound Editor |
| Manuela Gómez Estrada | Sound Editor |
| Giancarlo Granata | Sound Effects Editor |
| Marco Toca Ramirez | Sound Editor |
| Jason Richard Miller | Visual Effects Producer |
| Yvonne Reddy | Costume Design |
| Greg McDougall | Special Effects Makeup Artist |
| Steve Moore | Music |
| Emily Gotto | Executive Producer |
| Joe Wicker | Line Producer |
| Mark Ward | Executive Producer |
| Samuel Zimmerman | Executive Producer |
| Kim Barnard | Co-Producer |
| Rebecca Howard | Associate Producer |
| Jack N. Gracie | Editor |
| Tracy Kilpatrick | Casting |
| Joe Wicker | Unit Production Manager |
| Nicholas Clark | Second Assistant Director |
| Darius Young | Property Master |
| David Crane | Dialogue Editor |
| Will Denson | Sound Mixer |
| Elizabeth Davidovich | Stunts |
| Andy Rusk | Stunts |
| Kellen Turner | Costume Supervisor |
| Olivia Schlichting | Music Supervisor |
