 | Jason Marsden als Michael (voice) |
 | Lindsay Parker als Corey (voice) |
 | Townsend Coleman als Dad / Michaelangelo (voice) |
 | Laurie O'Brien als Mom / Baby Miss Piggy (voice) |
 | Jeff Bergman als Bugs Bunny / Daffy Duck (voice) |
 | Jim Cummings als Winnie-the-Pooh / Tigger (voice) |
 | George C. Scott als Smoke (voice) |
 | Frank Welker als Slimer / Hefty Smurf / Baby Kermit (voice) |
 | Russi Taylor als Baby Gonzo / Huey / Dewey / Louie (voice) |
 | Janice Karman als Theodore (voice) |
 | Paul Fusco als ALF (voice) |
 | Lorenzo Music als Garfield (voice) |
 | Joey Dedio als The Dealer (voice) |
 | Don Messick als Papa Smurf (voice) |
 | Danny Goldman als Brainy Smurf (voice) |
 | Ross Bagdasarian, Jr. als Alvin / Simon (voice) |
 | Wayne Collins als Additional Voices |
 | Aaron Lohr als Additional Voices |
| Georgie Irene als Additional Voices |
| Angella Kaye als Additional Voices |
 | George H. W. Bush als Himself |
 | Barbara Bush als Herself |
| Milton Gray | Director |
| Marsh Lamore | Director |
| Bob Shellhorn | Director |
| Mike Svayko | Director |
| Karen Peterson | Director |
| Roy Allen Smith | Producer |
| Diane Steinmetz | Producer |
| Andy Luckey | Producer |
| Duane Poole | Writer |
| Tom Swale | Writer |
| Richard Kosinski | Music |
| Sam Winans | Music |
| Paul Buckmaster | Music |
| Bill Reichenbach | Music |
| Bob Mann | Music |
| Guy Moon | Music |
| Jay Bixsen | Editor |
| Barry E. Jackson | Art Department Manager |
| Alan Menken | Music |
| Howard Ashman | Lyricist |
| Roy Edward Disney | Executive Producer |
| Steve Tyrell | Music Director |
| Takashi | Art Direction |
| Alex Nino | Background Designer |
| Mary Ann Steward | Color Designer |
| Roy Allen Smith | Associate Producer |
| Diane Steinmetz | Associate Producer |
| Linda Loe | Production Coordinator |
| Mark Low | Production Assistant |
| Cynthia Wilbur | Production Assistant |
| Adrian Gonzalez | Storyboard |
| Karen Peterson | Supervising Animation Director |
| Don Morgan | Art Direction |
| Buzz Potamkin | Producer |
