 | Rupert Everett als Bayardo San Roman |
 | Ornella Muti als Angela Vicario |
 | Gian Maria Volonté als Dr. Cristo Bedoya |
 | Lucía Bosè als Placida Linero |
 | Anthony Delon als Santiago Nasar |
 | Alain Cuny als El Viudo Xius |
 | Sergi Mateu als Giovane Cristo Bedoya |
 | Vicky Hernández als Clotilde Armenta |
 | Caroline Lang als Margot |
 | Carolina Rosi als Flora Miguel |
 | Silverio Blasi als Coronel Aponte |
| Sergi Mateu als Giovani Cristof |
| Carlos Miranda als Pidro Vicario |
 | Rogerio Miranda als Pablo Vicario |
| Leonor Gonzales als Victoria Guzman |
 | Edgardo Román als Faustino Santos |
 | Irene Papas als Madre de Angela |
 | Lucy Martínez |
| Francesco Rosi | Director |
| Tonino Guerra | Screenplay |
| Francesco Rosi | Screenplay |
| Pasqualino De Santis | Director of Photography |
| Ruggero Mastroianni | Editor |
| Piero Piccioni | Original Music Composer |
| Gabriel García Márquez | Novel |
| Andrea Crisanti | Production Design |
| Enrico Sabbatini | Costume Design |
| Francis von Büren | Producer |
| Francesco Rosi | Adaptation |
| Tonino Guerra | Adaptation |
| Andrea Crisanti | Set Decoration |
| Xavier Gélin | Associate Producer |
| Felipe López Caballero | Associate Producer |
| Yves Gasser | Producer |
| Jean-José Richer | Executive Producer |
| Carlo Lastricati | First Assistant Director |
| Gianni Arduini | First Assistant Director |
| Salvatore Basile | First Assistant Director |
| Claudia Gómez | Second Assistant Director |
| Eric Dionysius | Second Assistant Director |
| Paolo Piria | Production Manager |
| Christine Renaud | Production Manager |
| Gérald Morin | Production Manager |
| Franco Bruni | Camera Operator |
| Massimiliano Sano | Camera Operator |
| Marco Cristiani | Assistant Camera |
| Roberto De Nigris | Assistant Camera |
| Marco Pontecorvo | Assistant Camera |
| Mario Tursi | Still Photographer |
| Rachel Griffiths | Script Supervisor |
| Pierre Gamet | Sound |
| Bernard Chaumeil | Boom Operator |
| Giuliano Laurenti | Makeup Artist |
| Maurizio Silvi | Makeup Artist |
| Federico Laurenti | Makeup Artist |
| Walter Cossu | Makeup Artist |
| Elda Magnanti | Hairstylist |
| Renata Magnanti | Hairstylist |
| Silvana Senzacqua | Hairstylist |
| Paolo Borselli | Hairstylist |
| Flore Marina Sandoval | Hairstylist |
| Luciano Pecoraro | Production Supervisor |
| Jacqueline Lemaitre | Production Secretary |
| Gaetano Pesaro | Production Secretary |
| Josselyne Bucciali | Production Secretary |
| Albamaria Ruggieri | Production Secretary |
| Gianni Conti | Production Secretary |
| Angela Montoya | Production Assistant |
| Dominique Rausis | Production Assistant |
| Janine Constantin | Production Assistant |
| Felipe Aljure | Production Assistant |
| Marco Canevari | Assistant Production Design |
| Mauro Passi | Assistant Set Decoration |
| Giovanni Viti | Assistant Costume Designer |
| Uliva Pizzetti | Assistant Costume Designer |
| Rosario Lozano | Assistant Costume Designer |
| Luciano Leoni | Gaffer |
| Cecilia Catalucci | Assistant Editor |
| Olga Sarra | Assistant Editor |
| Marilena Cavola | Assistant Editor |
| Franco Tamponi | Conductor |
