 | Al Pacino als Danny Collins |
 | Annette Bening als Mary Sinclair |
 | Christopher Plummer als Frank Grubman |
 | Jennifer Garner als Samantha Leigh Donnelly |
 | Bobby Cannavale als Tom Donnelly |
 | Nick Offerman als Guy DeLoach |
 | Josh Peck als Nicky Ernst |
 | Katarina Čas als Sophie |
 | Giselle Eisenberg als Hope Donnelly |
 | Melissa Benoist als Jamie |
 | Scott Lawrence als Dr. Ryan Kurtz |
 | Brian Thomas Smith als Judd |
 | Michael Patrick McGill als Neighbor Steve |
 | Kiff VandenHeuvel als Marty |
 | Eric Michael Roy als Young Danny Collins |
 | Davide Donatiello als Young Danny Collins |
 | Eric Lange als Dr. Silverman |
 | Aarti Mann als Nurse Nikita |
 | Joshua Sternlicht als Josh the Bartender |
 | Travis Johns als Roadie |
 | Tim Jo als Tim |
| Hiroshi Moroto als Autograph Seeker |
 | Margy Moore als Hotel Bar Patron |
 | Eric Newnham als Hotel Bar Patron |
| Francine Levinson als Night Club Fan |
 | Hal Alpert als Night Club Fan |
| Henri C. Wittelsohn als Night Club Fan |
| Patrick Kudej als Chime In Magazine Intern |
| Carmel Echols als Danny's Background Singer |
 | Judith Hill als Danny's Background Singer |
| Kari Kimmel als Danny's Background Singer |
 | Don Was als Danny's Band |
 | CJ Vanston als Danny's Band |
| Kenny Aronoff als Danny's Band |
| Tim Pierce als Danny's Band |
| Mindi Abair als Danny's Band |
 | Bill Cantos als Danny's Band |
| George Doering als Danny's Band |
| Darrell Leonard als Danny's Band |
 | Kristin Brock als Kissing Couple (uncredited) |
| Elsi Eng als Eye Candy (uncredited) |
 | Olivia Gonzales als Ballerina (uncredited) |
 | Laura Krystine als Ballerina (uncredited) |
 | Anne McDaniels als Danny's Doll (uncredited) |
 | Roz McHenry als Red Vine Lady #1 (uncredited) |
 | Elaine Partnow als Red Vine Lady #2 (uncredited) |
| Jane Shayne als Red Vine Lady #3 (uncredited) |
 | Cassandra Starr als Groupie (uncredited) |
 | Linda Wang als Asian Fan #2 (uncredited) |
 | Richard Allan Jones als Party Guest (uncredited) |
| Dan Fogelman | Director |
| Dan Fogelman | Screenplay |
| Bill Corso | Makeup Department Head |
| Christopher Brown | Art Direction |
| Ryan Adams | Music |
| Nimitt Mankad | Producer |
| Declan Baldwin | Executive Producer |
| Theodore Shapiro | Music |
| Julie Monroe | Editor |
| Dan Bishop | Production Design |
| Jessie Nelson | Producer |
| Denise Di Novi | Executive Producer |
| Sophie de Rakoff | Costume Design |
| Monica Levinson | Executive Producer |
| Shivani Rawat | Executive Producer |
| Mindy Marin | Casting |
| Claudette Didul | Set Decoration |
| Carlos Castillon | First Assistant Editor |
| Steve Yedlin | Director of Photography |
| Jody Spilkoman | Second Assistant Director |
| Julianne Jordan | Music Supervisor |
| Julia Michels | Music Supervisor |
| Matt Sullivan | Music Supervisor |
| Monica Levinson | Unit Production Manager |
| Betsy Magruder | First Assistant Director |
| Alex Daniels | Stunt Coordinator |
| Jamie D. Boscardin | Production Supervisor |
| Nancy Kirhoffer | Post Production Supervisor |
| Andrew Hull | Assistant Art Director |
| Erin Magill | Assistant Art Director |
| Evan Regester | Graphic Designer |
| Kama Hayes | Art Department Coordinator |
| Jefferson Murff | Set Decoration |
| Bart C. Hubenthal | Set Dresser |
| Armando Alvarado | Set Dresser |
| Jose Castillo | Set Dresser |
| Johnny Lieberman | Set Dresser |
| Hugh Pritchard | Set Dresser |
| Charles Randolph | Set Dresser |
| Jayne-Ann Tenggren | Script Supervisor |
| Dale Myrand | Camera Operator |
| Henry Tirl | Camera Operator |
| Robert C. Carlson | Camera Operator |
| Peter Gulla | Camera Operator |
| Whitney Galitz | Assistant Costume Designer |
| David Swope | Costume Supervisor |
| Jason M. Moore | Key Costumer |
| Amber Jordyn | Set Costumer |
| Roberta Bilé | Set Costumer |
| Cheryl Ann Nick | Key Makeup Artist |
| Cheryl Ann Nick | Makeup Artist |
| Julie Hewett | Makeup Artist |
| Deborah La Mia Denaver | Makeup Artist |
| Patricia Almeida | Hair Department Head |
| Robert Wilson | Key Hair Stylist |
| Peter Tothpal | Hairstylist |
| Scott Harber | Sound Mixer |
| Kevin Hannigan | Special Effects Coordinator |
| Anthony Simonaitis | Special Effects Coordinator |
| Lynn Struiksma | Second Second Assistant Director |
| Dennis Burrell | Additional Second Assistant Director |
| Sylwia K. Dudzinska | Additional Second Assistant Director |
| Lynne Martin | Additional Second Assistant Director |
| Kara Lipson | Casting Associate |
| Lilia Trapani | Casting Director |
| Bac DeLorme | Second Unit First Assistant Director |
| Dale Stern | Second Unit First Assistant Director |
| Jason Roberts | Second Second Assistant Director |
| Paul Schmitz | Second Second Assistant Director |
| Christopher Blauvelt | Second Unit Director of Photography |
| Perry Robertson | Supervising Sound Editor |
| Scott Sanders | Sound Designer |
| Kevin Zimmerman | Sound Editor |
| John Ross | Sound Re-Recording Mixer |
| Kaspar Hugentobler | Sound Re-Recording Mixer |
| David Gaddie | Visual Effects Supervisor |
| Nick Crist | Visual Effects Supervisor |
| Angela Bowen | Visual Effects Producer |
