 | Jake Gyllenhaal als Adam Bell / Anthony Claire |
 | Mélanie Laurent als Mary |
 | Sarah Gadon als Helen Claire |
 | Isabella Rossellini als Adam's Mother |
 | Joshua Peace als Carl |
 | Tim Post als Anthony |
 | Kedar Brown als Security Guard |
 | Darryl Dinn als Video Store Clerk |
 | Megan Mane als Lady in the Dark Room |
 | Misha Highstead als Lady in the Dark Room |
 | Alexis Uiga als Lady in the Dark Room |
 | Kiran Friesen als Sad, Broken Woman (uncredited) |
 | Loretta Yu als Receptionist (uncredited) |
 | Stephen R. Hart als Bouncer (uncredited) |
| Paul Stephen als Dark Room Patron (uncredited) |
| Niv Fichman | Producer |
| Renée April | Costume Design |
| François Ivernel | Executive Producer |
| Cameron McCracken | Executive Producer |
| Jim Lambie | Set Decoration |
| José Saramago | Novel |
| Victor Loewy | Executive Producer |
| Javier Gullón | Writer |
| Patrice Vermette | Production Design |
| Denis Villeneuve | Director |
| Mark Slone | Executive Producer |
| Nicolas Bolduc | Director of Photography |
| Saunder Jurriaans | Original Music Composer |
| Matthew Hannam | Editor |
| Sean Breaugh | Art Direction |
| Danny Bensi | Original Music Composer |
| Miguel A. Faura | Producer |
| Morag Ross | Makeup Artist |
| Catherine Viot | Makeup Artist |
| Sam Hudecki | Storyboard Artist |
| Marc Orts | Sound Re-Recording Mixer |
| Marc Bech | Sound Editor |
| Marc Bech | Sound Re-Recording Mixer |
| Oriol Tarragó | Sound Designer |
| Oriol Tarragó | Supervising Sound Editor |
| Alison Reid | Stunt Coordinator |
| Debra Johnson | Makeup Artist |
| Martha Sparrow | Set Designer |
| Albert Ribas | Sound Editor |
| Herwig Gayer | Production Sound Mixer |
| Jennifer Vey | Stunt Double |
| John MacLean | Key Grip |
| Jordan Kerner | Set Dresser |
