 | Jessica Chastain als Tammy Faye Bakker |
 | Andrew Garfield als Jim Bakker |
 | Cherry Jones als Rachel Grover |
 | Vincent D'Onofrio als Jerry Falwell |
 | Mark Wystrach als Gary Paxton |
 | Sam Jaeger als Roe Messner |
 | Louis Cancelmi als Richard Fletcher |
 | Gabriel Olds als Pat Robertson |
 | Fredric Lehne als Fred Grover |
 | Chandler Head als Little Tammy Faye |
 | Jay Huguley als Jimmy Swaggart |
 | Dan Johnson als Preacher |
 | Michael MacCauley als Big Man |
| Grant Owens als Colonel Sanders |
 | Coley Campany als DeDe Robertson |
| Craig Newkirk als Doctor |
 | Wes Jetton als Male Nurse |
 | Jess Weixler als Makeup Artist (voice) |
| Maurie Speed als Nurse |
 | Lindsay Ayliffe als Old Teacher (Bible College) |
| Julie P. Tuggle als Pledge Lady |
 | Kimberly Ann Parker als Reporter |
| Dana Marks als True Believer |
 | Alan Boell als Stephen Chow |
 | Randy Havens als Steve Pieters |
| Lila Jane Meadows als Tammy Sue |
| Carolyn Mints als Wanda |
| Kelly Borgnis als PTL Patron |
 | Kelsi Chandler als PTL Patron |
 | Joe Ando-Hirsh als Teenage Punk #1 |
| John Johnson als Teenage Punk #2 |
| Grayson Carter als Teenage Punk #3 |
| Callie Lipian als Jamie Charles Bakker (Baby) |
| Caroline Lipian als Tammy Sue Bakker (Baby) |
| Robert Bailey als Nashville Singer |
| Deb Thomas Cox als Nashville Singer |
| Ellen Dockery als Nashville Singer |
| Jana King Evans als Nashville Singer |
| Lee Hilliard als Nashville Singer |
| Mark Ivey als Nashville Singer |
| Michael B. Lusk als Nashville Singer |
| Craig Morris als Nashville Singer |
| Savannah Morris als Nashville Singer |
| Donna Rhodes als Nashville Singer |
| Kira Small als Nashville Singer |
| Allen Andrews als PTL Sax Player (uncredited) |
 | Chris TC Edge als PTL Crew Member (uncredited) |
 | Kyle Riggs als Jamie Charles Bakker (uncredited) |
 | Alan Dale als Self (archive Footage) |
 | Hugh Downs als Self (archive Footage) |
 | Jay Leno als Self (archive Footage) |
 | Ronald Reagan als Self (archive Footage) |
| Christian Goins als Little Danny |
| Jessica Chastain | Producer |
| Rachel Shane | Producer |
| Michael Showalter | Director |
| Jordana Mollick | Executive Producer |
| Kelly Carmichael | Producer |
| Gigi Pritzker | Producer |
| Mike Gioulakis | Director of Photography |
| Mary Jo Markey | Editor |
| Adrian Alperovich | Executive Producer |
| Fenton Bailey | Executive Producer |
| Randy Barbato | Executive Producer |
| Jenny Hinkey | Executive Producer |
| Meredith Milton | Executive Producer |
| Andrew Weisblum | Editor |
| Avy Kaufman | Casting |
| Laura Fox | Production Design |
| Charles Varga | Art Direction |
| Barb Livingston | Set Decoration |
| Mitchell Travers | Costume Design |
| Randi Owens Arroyo | Makeup Artist |
| Ashleigh Chavis | Key Makeup Artist |
| Linda Dowds | Makeup Artist |
| Linda Dowds | Makeup Department Head |
| Renee Goodwin | Makeup Artist |
| Cecilia Verardi | Makeup Artist |
| Mike Cavell | Sound Mixer |
| Greg Crawford | ADR Mixer |
| Russell Farmarco | ADR Supervisor |
| Taylor Flinn | Sound Effects Editor |
| Mike Horton | Foley Artist |
| Sang Jun Kim | Supervising Dialogue Editor |
| Wayne Lemmer | Supervising Sound Editor |
| Wayne Lemmer | Sound Re-Recording Mixer |
| Eric A. Norris | Sound Designer |
| Walter Spencer | Foley Supervisor |
| Kevin Ledford | Special Effects Technician |
| Bryan Sides | Special Effects |
| Jared Levin | Visual Effects Coordinator |
| Patrick Thomas O'Rourke | Visual Effects Production Manager |
| Fenner Rockliffe | Digital Compositor |
| Elias Saliba | Compositor |
| Ron South | Visual Effects Editor |
| Jason Fabbro | Visual Effects |
| Blake Goedde | Compositing Supervisor |
| Jenny Hinkey | Unit Production Manager |
| Cal Johnson | Stunt Coordinator |
| T.K. Knowles | Associate Producer |
| John O'Grady | Associate Producer |
| Dee Blackburn | Set Designer |
| Jessica Tyler Segal | Art Department Coordinator |
| Tiffany Apple Keenan | Graphic Designer |
| Theodore Shapiro | Original Music Composer |
| Kim Chewning | Costume Supervisor |
| Claire Dudley | Set Costumer |
| Amber Givens | Set Costumer |
| Abe Sylvia | Writer |
| Stephanie Ingram | Hair Department Head |
| Justin Raleigh | Special Effects Makeup Artist |
| Mitchel Wolf | Assistant Costume Designer |
