 | Tom Hardy als Eddie Brock / Venom |
 | Woody Harrelson als Cletus Kasady / Carnage |
 | Michelle Williams als Anne Weying |
 | Naomie Harris als Frances Louise Barrison / Shriek |
 | Reid Scott als Dr. Dan Lewis |
 | Stephen Graham als Detective Mulligan |
 | Peggy Lu als Mrs. Chen |
 | Sian Webber als Dr. Pazzo |
 | Michelle Greenidge als Mugging Victim |
| Rob Bowen als Beaten Mugger |
 | Laurence Spellman als Patient |
 | Little Simz als Little Simz |
 | Jack Bandeira als Young Cletus |
 | Olumide Olorunfemi als Young Shirek |
 | Scroobius Pip als Siegfried |
 | Amrou Al-Kadhi als Host Two |
| Beau Sargent als Host Three |
 | Brian Copeland als Rodeo Beach Reporter |
 | Stewart Alexander als Warden |
 | Sean Delaney als Young Detective Mulligan |
 | Ed Kear als Reveler |
 | Emma Lau als Reveler |
| Louis j Rhone als Reveler |
 | Christopher Godwin als Headmaster (1997) |
 | Tiffanie Thomas als San Quentin Tier Guard |
 | Rocky Capella als Valet Car Park |
| Sam Robinson als San Quentin Guard |
 | Greg Lockett als San Francisco Police Department Officer |
 | Sonny Ashbourne Serkis als Plunger Man |
 | Otis Winston als Street Man |
| Vaughn Johseph als Tie Down Guard |
| Kristen Simoes als TV Reporter - San Quentin |
| Miguel Angel Arreguin als Gas Station Attendant |
| Shaliz Afshar als San Francisco Reporter |
 | Reece Shearsmith als Priest |
 | Simon Connolly als Grieving Father |
 | Rachel Handshaw als Grieving Mother |
 | Amanda Foster als Victim's Sister |
 | Akie Kotabe als Victim's Brother |
 | Eric Sigmundsson als Startled Witness |
 | Chabris Napier-Lawrence als Ravenscroft Guard |
 | Larry Olubamiwo als Ravenscroft Guard |
 | Jose Palma als San Quentin Last Meal Guard |
| Ashlen Aquila als San Quentin Last Meal Guard |
 | Jamal Ajala als Ravenscroft Orderly |
 | James D. Weston II als San Quentin Commander |
| Che Amaro als San Quentin Guard |
| Joshua Eldridge-Smith als Sympathetic Guard |
| Rosie Marcel als Detective in Bathroom |
| Elliot Cable als Host Pre Carnival #1 |
 | J.K. Simmons als J. Jonah Jameson (uncredited) |
 | Tom Holland als Peter Parker / Spider-Man (uncredited) |
 | Stan Lee als Stan Lee (Archive Footage Uncredited) |
 | David Zepeda als Max Irázabal (uncredited) |
| Matt Tolmach | Producer |
| Avi Arad | Producer |
| Amy Pascal | Producer |
| Robert Richardson | Director of Photography |
| Oliver Scholl | Production Design |
| Hutch Parker | Producer |
| David Michelinie | Characters |
| Todd McFarlane | Characters |
| Mark Bagley | Characters |
| Tom DeFalco | Characters |
| Andy Serkis | Director |
| Angus More Gordon | Co-Producer |
| Marco Beltrami | Original Music Composer |
| Kelly Marcel | Screenplay |
| Kelly Marcel | Story |
| Kelly Marcel | Producer |
| Tom Hardy | Producer |
| Barry H. Waldman | Executive Producer |
| Jonathan Cavendish | Executive Producer |
| Ruben Fleischer | Executive Producer |
| Tom Brown | Supervising Art Director |
| Michael E. Goldman | Art Direction |
| Simon Lamont | Art Direction |
| Troy Sizemore | Supervising Art Director |
| Malcolm Stone | Art Direction |
| Alex Brandenburg | Set Decoration |
| Dominic Capon | Set Decoration |
| Joanna Eatwell | Costume Design |
| Jess Clarke | Makeup Artist |
| Elizabeth Fox | Makeup Artist |
| Angela Levin | Makeup Artist |
| Mona Turnbull | Makeup Artist |
| Frances Darvell White | Makeup Artist |
| Calvin Richard Evans Watson | Sound Designer |
| Brian Adler | Visual Effects |
| Daniel Booty | Visual Effects Producer |
| Russell Bowen | Visual Effects Supervisor |
| Paul Boyd | Visual Effects |
| Maryann Brandon | Editor |
| Stan Salfas | Editor |
| Sheena Duggal | Visual Effects Supervisor |
| James M. Churchman | Stunt Coordinator |
| George Kirby | Fight Choreographer |
| Kami Asgar | Supervising Sound Editor |
| Beau Borders | Sound Re-Recording Mixer |
| Matt Cavanaugh | Sound Effects Editor |
| Justin M. Davey | Sound Effects Editor |
| Sam Fan | Sound Effects Editor |
| Will Files | Sound Re-Recording Mixer |
| Will Files | Sound Designer |
| Ken McGill | Sound Effects Editor |
| Kevin O'Connell | Sound Re-Recording Mixer |
| Erin Oakley | Supervising Sound Editor |
| Robert Stambler | Sound Designer |
| Chris Terhune | Sound Effects Editor |
| Matt Yocum | Sound Effects Editor |
| Aviv Bar-Ami | VFX Artist |
| Alvaro Garcia | VFX Artist |
| Emanuele Goffredo | VFX Artist |
| Jared Hasselbach | VFX Artist |
| Barrie Hemsley | Visual Effects Producer |
| Ankur Mishra | VFX Artist |
| Lucy Bevan | Casting |
| Brian Smrz | Second Unit Director |
| Barry H. Waldman | Unit Production Manager |
| Brent O'Connor | Unit Production Manager |
| K.C. Hodenfield | First Assistant Director |
| Max Sturgeon | Second Assistant Director |
| Barrie Hemsley | Co-Producer |
| K.C. Hodenfield | Co-Producer |
| Jane Tones | Additional Editing |
| Marco Scotti | Costume Supervisor |
| Shailesh Chibire | Modeling |
| Christoph Westphal | VFX Artist |
| Tom Hardy | Story |
| Mary Buri | Standby Art Director |
| Chris Evans-Wilson | Assistant Art Director |
| Lara Genovese | Set Designer |
| Solomon Honey | Assistant Art Director |
| Loren Hoselton | Set Dresser |
| Olivia Kanz | Set Dresser |
| Ian Way | Set Dresser |
| Jake Collier | Set Costumer |
| Caroline Levy | Line Producer |
| Ramon Álvarez | Stunts |
| Leo Woodruff | Stunts |
| Natalie Wood | Stunts |
| Belle Williams | Stunt Double |
| Steven Whitley | Stunts |
| Nicolas Wang | Stunts |
| Elmo Walker | Stunts |
| Chris Waite | Stunts |
| Tony Vella | Stunts |
| Luke Tumber | Stunts |
| Luke Tumber | Stunt Driver |
| Jacob Tomuri | Stunt Double |
| Harvey Taylor | Stunts |
| John Street | Stunt Driver |
| Matthew Stirling | Stunts |
| Shane Steyn | Stunts |
| Anton Simpson-Tidy | Stunts |
| Luke Scott | Stunts |
| Liva Rafidison | Stunt Double |
| Oleg Podobin | Stunts |
| Laurent Plancel | Stunts |
| Christina Petrou | Stunts |
| Tomás Paredes | Stunts |
| Vinny O'Brien | Stunt Double |
| Andrew J. Neis | Stunts |
| Andrew J. Neis | Stunt Double |
| Andrew J. Neis | Stunt Driver |
| Steven Mullins | Stunts |
| Nikita Mitchell | Stunt Double |
| Nikita Mitchell | Stunts |
| Andrew Mew | Stunts |
| Andy Merchant | Stunts |
| Mike Martinez | Stunts |
| Jean-Paul Ly | Stunts |
| Lukaz Leong | Stunts |
| Reuben J. Lee | Stunts |
| André Layne | Stunt Driver |
| Josh Lakatos | Stunt Driver |
| Luke Kearney | Stunts |
| Jindřich Klaus | Stunts |
| Robert Hladik | Stunt Driver |
| James Harris | Stunts |
| Tom Hallahan | Stunts |
| Martin Gordon | Stunts |
| Paul Ginns | Stunts |
| Grace Franzl | Stunts |
| Amanda Foster | Stunts |
| Ben Essex | Stunts |
| James Embree | Stunt Double |
| Sam Durrani | Stunt Double |
| Levan Doran | Stunts |
| Lisa Dempsey | Stunts |
| Arie Dekker | Stunts |
| Nicholas Daines | Stunts |
| Joel Conlan | Stunts |
| Yusuf Chaudhri | Stunts |
| Carlos Castillo | Stunts |
| Pablo Casillas | Stunts |
| Tony Carbajal | Stunt Double |
| Rocky Capella | Stunts |
| Marvin Campbell | Stunts |
| Dacio Caballero | Stunts |
| Nellie Burroughes | Stunts |
| Andrew Burford | Stunts |
| Adam Bowman | Stunts |
| Rob Bowen | Stunt Double |
| Rob Bowen | Stunts |
| Adam Basil | Stunt Double |
| Ashlen Aquila | Stunts |
| Sina Ali | Stunts |
| Reetu Aggarwal | 3D Artist |
| Jeff Mosley | Stunt Double |
| Duy Pham | Visual Effects |
| Eminem | Songs |
| Christopher Ferguson | Lighting Programmer |
| Kevin Day | Props |
| Fabian Wagner | Additional Photography |
