 | Elizabeth Perkins als Skye Weston |
 | Bradley Whitford als Rick Weston |
 | Scott Paulin als John Gryce |
 | Enrico Colantoni als Steve Rinker |
 | Tina Lifford als Claire Barnes |
 | Alan Rosenberg als Dr. Wesley Kozak |
 | Hrothgar Mathews als Dr. Mason |
 | Chilton Crane als Beth Curtis |
 | Alexander Pollock als Timmy/ Chris |
 | Fulvio Cecere als Agent Briggs |
 | Bill Dow als Alan Prescott |
 | David Kaye als Reid Kennedy |
 | Paul Batten als Banker #2 |
 | Roger Cross als Frank Zago |
 | Eric Keenleyside als Counterman |
 | Brandon Heuser als Store Clerk |
 | Jay Arlen Jones als Father of Newborn |
| Tina Hildebrandt als Mother of Newborn |
| Gerry Durand als Man on Elevator |
 | June B. Wilde als Parent of Clone |
 | Karen Kruper als Parent of Clone |
 | David Neale als Parent of Clone |
 | Althea McAdam als Woman in Hallway |
 | Wendy Van Riesen als Agent Fuller |
| Douglas Barr | Director |
| Perri Klass | Story |
| Carmen Culver | Story |
| Raúl Dávalos | Editor |
| Eileen Mack Knight | Casting |
| Randy Chodak | Art Direction |
| James G. Fisher | Special Effects Coordinator |
| Donald Gillard | Special Effects |
| Lee Wilson | Visual Effects Supervisor |
| Yves Cameron | Stunt Coordinator |
| Lori Stewart | Stunts |
| J.J. Makaro | Stunt Coordinator |
| Marty Wereski | Music Editor |
| Terry J. Murray | Script Supervisor |
| Ian Overend | Location Manager |
| Justin Bourret | Editorial Production Assistant |
| Rick Davidson | Camera Operator |
| Peter G. Capadouca | Gaffer |
| Gina Sherritt | Hairstylist |
| Tish Monaghan | Costume Design |
| Lesley Beale | Set Decoration |
| Robin Forman | Producer |
| Paula Weinstein | Executive Producer |
| Mark Noda | Boom Operator |
| Gordon Anderson | Production Sound Mixer |
| Wayne Artman | Sound Re-Recording Mixer |
| Bob Costanza | Supervising Sound Editor |
| Tommy Goodwin | Foley |
| Robert L. Harman | Sound Re-Recording Mixer |
| Frank Jones | Sound Re-Recording Mixer |
| Danny Ho | Special Effects |
| Mark Snow | Original Music Composer |
| Malcolm Cross | Director of Photography |
| David Taylor | Writer |
| Carmen Culver | Writer |
| Brent Thomas | Production Design |
| Sid Feders | Co-Executive Producer |
| Abby Wolf-Weiss | Co-Executive Producer |
