 | David Harbour als Hellboy / Anung Un Rama |
 | Milla Jovovich als Vivienne Nimue, the Blood Queen |
 | Ian McShane als Trevor "Broom" Bruttenholm |
 | Sasha Lane als Alice Monaghan |
 | Daniel Dae Kim als Ben Daimio |
 | Thomas Haden Church als Lobster Johnson |
 | Stephen Graham als Gruagach (voice) |
 | Douglas Tait als Gruagach |
 | Sophie Okonedo als Lady Hatton |
 | Alistair Petrie als Lord Adam Glaren |
 | Brian Gleeson als Merlin |
 | Penelope Mitchell als Ganeida |
 | Mark Stanley als Arthur |
 | Emma Tate als Baba Yaga (voice) |
 | Troy James als Baba Yaga |
 | Mario de la Rosa als Esteban Ruiz / Camazotz |
 | Ava Brennan als Alice's Mother |
 | Anthony Delaney als Alice's Father |
 | Atanas Srebrev als Agent Madison |
 | Dawn Sherrer als Agent Strode |
 | Markos Rounthwaite als Grigori Rasputin |
| Ilko Iliev als Professor Doctor Karl Ruprecht Kroenen |
 | Joel Harlow als Von Krupt |
| Dimiter Banenkin als Leopold Kurtz |
 | Vanessa Eichholz als Ilsa Hepstein |
 | Nadya Keranova als Sister #1 |
 | Maria Tepavicharova als Sister #2 |
 | Ana Tabakova als Sister #3 |
| Terry Randal als Priest |
| Christopher Mata als Referee |
 | Michael Heath als Butler |
 | Rick Warden als Dr. Edwin Carp |
 | Nitin Ganatra als August Swain |
 | Kristina Klebe als Leni Riefenstahl |
| Charles Shannon als Sgt. Whitman |
| Carl Hampe als Sir Malcom Frost |
 | Tony van Silva als Abbot |
 | Josh Finan als Novice |
| Jonathan Steele als Huntsman |
| Simon Feek als M-11 Operative |
| Jasmine Audoux-Prevot als Baby Alice |
 | Meglena Karalambova als Leprous Hag #1 |
| Anna Bankina als Leprous Hag #2 |
| Rut Rafailova als Leprous Hag #3 |
 | Laila Morse als Mrs. Harker |
| Peter Oxley als Gunsmith |
| Nikolay Stanoev als Monk |
 | Manal El-Feitury als Mother |
| Elizabeth Mehari Kahsai als Child in Parking Lot #1 |
| Said Barry Abdulai als Child in Parking Lot #2 |
| Katya Peneva als Sarah Bethany Hughes |
| Natasha Kaplinsky als Anchorwoman |
| Valentin Stojanov als Man #1 |
| Victor Rangelov als Man #2 |
| Vasil Tsvetkov als Man #3 |
 | Joshua Samuel Hector als Man #4 |
 | John Wolfe als Horse Knight (uncredited) |
| Mike Mignola | Characters |
| Neil Marshall | Director |
| Andrew Cosby | Screenplay |
| Lawrence Gordon | Producer |
| Lloyd Levin | Producer |
| Mike Richardson | Producer |
| Christa Campbell | Producer |
| Lati Grobman | Producer |
| Paul Kirby | Production Design |
| Lorenzo Senatore | Director of Photography |
| Dessy Slavova | Stunt Double |
| Benjamin Wallfisch | Original Music Composer |
| Joel Harlow | Makeup Artist |
| Mike Mignola | Comic Book |
| Dan Hubbard | Casting |
| Martin Cantwell | Sound Designer |
| Les Weldon | Producer |
| Vladimir Kaloyanov | Sound Mixer |
| Rob Prynne | Sound Designer |
| Ivan Rangelov | Supervising Art Director |
| Nelly Teova | Key Hair Stylist |
| Stephanie Collie | Costume Designer |
| Philip Westgren | Producer |
| Steven Begg | Visual Effects Supervisor |
| Carl Hampe | Producer |
| Matthew O'Toole | Producer |
| Yana Stonayova | Makeup Designer |
| Diyan Hristov | Second Unit Director |
| Paul Carter | Sound Designer |
| Yariv Lerner | Producer |
| Martin Bernfeld | Editor |
| Matthew Collinge | Sound Supervisor |
| Joel Harlow | Creature Design |
| Geo Ivanov | Camera Operator |
| Andy Williams | Electrician |
| Ivo Peitchev | Second Unit Director of Photography |
| Todor Tunov | Construction Coordinator |
| Dimitar Krustev | Drone Pilot |
| Martin Nazlamov | Electrician |
| Gareth Brough | Electrician |
| Sergey Zhelezko | Epk Director |
| Steve Krasznai | Steadicam Operator |
| Mark Rogers | Still Photographer |
| Samuel Cig | Phantom Operator |
| Georgi Petkov | Key Grip |
| Alessandro Troso | Art Direction |
| Alison Harvey | Set Decoration |
| Valentina Mladenova | Set Decoration |
| Milen Stoilov | Electrician |
| Martin Ward | Video Assist Operator |
| Pat Crawford | Electrician |
| Atanas Stoyanov | Key Rigging Grip |
| Phil Humphries | Digital Imaging Technician |
| Gareth Sheldon | Electrician |
| Alexei Karagyaur | Art Direction |
| Mariana Videnova | Art Department Coordinator |
| Simon Tanner | Rigging Gaffer |
| Jon Beacham | Camera Operator |
| David Holliday | Key Grip |
| Peter Chester | Gaffer |
| Ivaylo Ivanov | Camera Operator |
| Ivo Hristov | Electrician |
| Stephen Hughes | Epk Camera Operator |
| Ian Bird | Key Grip |
| Tom Aldcroft | Aerial Camera |
| Hristo Idakiev | Gaffer |
| Sandro Magliano | Digital Imaging Technician |
| Daniela Avramova | Key Makeup Artist |
| Darren Hinchy | Visual Effects Editor |
| Luís Tinoco | Visual Effects Supervisor |
| John Haley | Visual Effects Supervisor |
| Katrin Arndt | Visual Effects Producer |
| Cyrielle Bounser | 3D Generalist |
| Lazarin Kouchev | 3D Supervisor |
| James Sutton | CG Supervisor |
| Alessandro Pantanella | Compositing Supervisor |
| Daniel Leung | Lighting Supervisor |
| Tom Balogh | Visual Effects Editor |
| Matt Kasmir | Visual Effects Supervisor |
| Lauren Jerome | Casting Assistant |
| Hrista Ilieva | Extras Casting |
| Johanna Elf | Assistant Costume Designer |
| Vyarka Sirkova | Set Costumer |
| James Kinnings | Animation Director |
| Greta Ruljevaite | Visual Effects Producer |
| Frederick Vallée | 3D Generalist |
| Loic Laurelut | Compositing Supervisor |
| Dominik Trimborn | Visual Effects Supervisor |
| Anna Gelinova | Costume Supervisor |
| Anshul Mathuria | 2D Supervisor |
| Sergey Kononenko | CG Supervisor |
| Cristian Camaroschi | CG Supervisor |
| B.R. Rajeev | CG Supervisor |
| Shruti Janu | Senior Animator |
| Violeta Lazarova | Key Hair Stylist |
| Claire Robinson | Casting Associate |
| Elena Melamed | Production Manager |
| Will Howden | Special Effects Coordinator |
| Andreas Giesen | CG Supervisor |
| Erik Schneider | Compositing Supervisor |
| Shaun Freeman | Lead Animator |
| Andrey Hristozov | Visual Effects Editor |
| Dobrinka Stamenkova | Costume Coordinator |
| Luca Buonopane | 3D Generalist |
| Kalin Stoyanov | VFX Artist |
| Doris Huber | Visual Effects Producer |
| Christopher Maslen | Visual Effects Supervisor |
| Richard Clarke | Visual Effects Supervisor |
| Georgi Dimitrov | Stunt Coordinator |
| Yanka Doychinova | Wigmaker |
| Katerina Goranova | Casting Assistant |
| Jan Dieckmann | Textile Artist |
| Tom Harris | Special Effects Supervisor |
| Chris MacLean | Visual Effects Supervisor |
| Stephanie Doherty | Contact Lens Technician |
| Amy Clarke | Costume Supervisor |
| Jesper Kjölsrud | VFX Supervisor |
| Alex Brueckner | Visual Effects Editor |
| Markus Degen | Visual Effects Supervisor |
| Marina Proykova | Set Costumer |
| Pablo M. Bravo | 3D Artist |
| Hannes Drossel | CG Supervisor |
| Anna Andreeva | Wigmaker |
| Georgi Petrov Yakimov | Costumer |
| Lyudmil Nikolov | Special Effects Supervisor |
| Luke Groves | Visual Effects Producer |
| Veselina Georgieva | Visual Effects Supervisor |
| Markos Rounthwaite | Stunt Coordinator |
| Lancel Reyes | Prosthetics |
| Neil Wallace | First Assistant Director |
| Janek Lender | Pre-Visualization Supervisor |
| Cameron Scott | VFX Supervisor |
| Nikolay Pachov | Visual Effects Editor |
| Roopesh Gujar | Visual Effects Producer |
| James Cooper | Visual Effects Supervisor |
| Georgi Manchev | Fight Choreographer |
| Cristina Patterson | Contact Lens Painter |
| Rosen Georgiev | Costumer |
| Davide Bigotto | 3D Generalist |
| Julia Strack | Compositing Supervisor |
| Nevena Dragoshinova | Visual Effects Editor |
| David Danesi | Visual Effects Producer |
| Martin Georgiev | Visual Effects Supervisor |
| Sinead Sweeney | Contact Lens Designer |
| Chris Diamantides | Wigmaker |
| Charlie Rotheram | Extras Casting |
| Antony Tanev | First Assistant Director |
| Ivo Hristov | 3D Artist |
| Lydia Kenton | 3D Generalist |
| Nadia Miltcheva | 3D Modeller |
| Matthias Winkler | CG Supervisor |
| Mark Brown | Pre-Visualization Supervisor |
| Kieran Waller | Visual Effects Editor |
| Sonia Marques | Visual Effects Producer |
| Marc Helwig | Executive Producer |
| Lilly Blazewicz | Foley Editor |
| Peter Burgis | Foley Artist |
| Paul Carter | Sound Designer |
| Mark DeSimone | ADR Mixer |
| Sean Evans | Sound Editor |
| Zoe Freed | Foley Artist |
| Glen Gathard | Foley Mixer |
| Rebecca Heathcote | Foley Artist |
| Chris Navarro | ADR Mixer |
| Adam Oakley | Foley Editor |
| Adam Bourne | Foley Editor |
| Johan Lindqvist | Motion Capture Artist |
| Mike Kerr | Songs |
| Ben Thatcher | Songs |
| Maya Markova | Third Assistant Director |
| Ivailo Dimitrov | Stunt Double |
| Dimiter Doichinov | Stunt Double |
| Asen Asenov | Stunts |
| Georgi Dimitrov | Stunts |
| Angel Angelov | Stunts |
| Miloslav Dimitrov | Stunts |
| Ivan Iliev | Stunt Double |
| Radoslav Ignatov | Stunt Double |
| Genko Ivanov | Stunt Double |
| Kiril Ivanov | Stunts |
| Alexander Hristov | Stunts |
| Viktor Hristov | Stunts |
| Milen Kaleichev | Stunts |
| Georgi Karadjov | Stunts |
| Donovan Louie | Stunt Double |
| Angel Lukanov | Stunts |
| Stilyan Mavrov | Stunt Double |
| Georgi Manchev | Stunts |
| Emil Petkov | Stunts |
| Rumen Petrov | Stunts |
| Radka Petkova | Stunt Double |
| Elitsa Razheva | Stunts |
| Victor Rangelov | Stunts |
| Vasil Simeonov | Stunts |
| Rayna Sirmina | Stunt Double |
| Valentin Stoyanov | Stunt Double |
| Simeon Spasov | Stunts |
| Kiril Todorov | Stunts |
| Tony van Silva | Stunt Driver |
| Svetislav Tsanov | Stunt Double |
| Vencislav Stojanov | Stunts |
| Tihomir Vinchev | Stunts |
| Ivan Vodenicharov | Stunts |
| John Wolfe | Stunts |
| Yordan Zahariev | Stunts |
| Vasil Yordanov | Stunts |
