 | Aneurin Barnard als Dr. Dylan Pearce |
 | Iwan Rheon als Meurig Jenkins |
 | Alexandra Roach als Ffion Jenkins |
 | Phaldut Sharma als Peetham ‘Pete’ Shah |
 | Paul Rhys als Tommy Cadogan |
 | Steffan Rhodri als Colin White |
 | Mark Lewis Jones als Eddie O’Connor |
 | Joanna Page als Moira Davies |
 | Lisa Palfrey als Teresa Rigby |
 | Alexandria Riley als Alys Shah |
 | Philippa Cole als Ceri Howell |
 | Nathan Sussex als Rhys Lancey |
 | Katy Wix als Joanna Wootle |
| Matthew Barry | Writer |
| Ashley Way | Director |
| Karen Lewis | Producer |
| Nicola Shindler | Executive Producer |
| Davina Earl | Executive Producer |
| Russell T Davies | Executive Producer |
| Matthew Barry | Executive Producer |
| Rebecca Ferguson | Executive Producer |
| Nick Andrews | Executive Producer |
| Rachel Evans | Executive Producer |
| Karen Lewis | Executive Producer |
| Ashley Way | Executive Producer |
| Jon Williams | Line Producer |
| Blair Mowat | Music |
| John Richards | Editor |
| Rachel Sheridan | Casting Director |
| Amelia Shankland | Production Designer |
| Kim Armitt | Art Direction |
| Muirelle Wilson | Set Decoration |
| Lucille Acevedo-Jones | Costume Designer |
| Sarah Astley | Makeup Supervisor |
| Sarah Astley | Hair Supervisor |
| Vikki Owen | Makeup & Hair Assistant |
| Mimi Rhys-Jones | Makeup Trainee |
| James Spinks | Makeup Designer |
| James Spinks | Hair Designer |
| Jakub Kyral | Production Secretary |
| Chris Leach | Head of Production |
| Siwan Phillips | Head of Production |
| Huw Jones | First Assistant Director |
| Gwawr Keyworth | Second Assistant Director |
| Elly Meredith | Third Assistant Director |
| Hywel Fanner | Assistant Art Director |
| Sam Filburn | Property Master |
| Ben Livingstone | Graphic Designer |
| Meish Quinn | Standby Art Director |
| Gwion Ynyr Roberts | Set Dresser |
| Richard Brooks | Sound Recordist |
| Simon H. Jones | Sound Re-Recording Mixer |
| Leslie Liu | ADR Mixer |
| Milos Stojanovic | Dialogue Editor |
| Marc Turner | Special Effects Supervisor |
| Lucy Lawson-Duckett | Visual Effects Producer |
| Jacob Percival | Visual Effects Editor |
| Jack Rhys Phillips | Visual Effects Supervisor |
| Peter Rogers | Visual Effects Producer |
| Tom Tatchell | Compositor |
| Antony Jenushan Thanarajaratnam | Compositor |
| Anthony Williams | Compositor |
| Llyr Williams | Compositor |
| Paul Edwards | Camera Operator |
| Paul Edwards | Steadicam Operator |
| Josh Greenway | Second Assistant Camera |
| Tom Jackson | Still Photographer |
| David Key | Second Assistant Camera |
| Alister Malcolm | Camera Trainee |
| Bob Milton | Electrician |
| Gawain Nash | Best Boy Grip |
| Nathan O'Kelly | Camera Operator |
| Rhiannon Pallister | Electrician |
| Trevor Speed | Camera Operator |
| Leighton Spence | Camera Operator |
| Leighton Spence | Steadicam Operator |
| Ed Stone | Drone Operator |
| Rob White | Gaffer |
| Katie Mozumder | Casting Associate |
| Fay Bescoby | Costume Standby |
| Rhiann Houlihan | Principal Costumer |
| Tess Raggett | Costume Supervisor |
| Emily Brauders | Post Producer |
| Jonny Garbutt | Digital Intermediate Colorist |
| Kevin Horsewood | Colorist |
| Gareth Mabey | Assistant Editor |
| Gareth Roberts | Location Manager |
| Dora Kmezic | Orchestrator |
| John McFarlane | Musician |
| Jack McKenzie | Orchestrator |
| Steve Wright | Additional Music |
| Denzel Adebayo | Script Editor |
| Llinos Wyn Jones | Script Supervisor |
| Catrin Rowlands | Story Consultant |
| Catrin Brooks | Production Coordinator |
| Fabiana Canale | Production Accountant |
| Samuel Griffiths | Floor Runner |
| Nyisha Mills | Production Runner |
| Analisa Vailloo | Assistant Accountant |
| Holly Parker | Choreographer |
| Adam Bradley | Medical Consultant |
| Matthew Lepper | First Assistant Camera |
| Maddie Ferguson | Camera Trainee |
| Matt Hains | Key Grip |
| Gareth Robinson | Assistant Grip |
| Jeff Dearing | Unit Manager |
| Morgan Parry | Location Assistant |
| Mark Bankhead | Online Editor |
| Adam Etherington | Director of Photography |
